“…Despite recent progresses in its treatment, malignant cutaneous melanoma remains a cancer with very poor prognosis. …”
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“…Melanoma is known to show considerable variation in its histopathological presentation. …”
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“…Uveal melanoma (UM) is the most common primary intraocular malignancy of the eye. …”
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“…RESULTS: A total of 48 361 patients were included: 79.3% had superficial spreading melanoma (SSM), 14.6% nodular melanoma (NM), 5.2% lentigo maligna melanoma, and 0.9% acral lentiginous melanoma (ALM). …”
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“…Primary gastric malignant melanoma (PGMM) is an extremely rare clinical entity, and few cases have been described in the literature. …”
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“…Metastatic melanoma may be included in the differential diagnosis of hyoid masses in patients with a history of melanoma. …”
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“…Leptomeningeal disease in patients with melanoma historically portends a grim prognosis, with median survival measured in weeks to months. …”
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“…Nasopharyngeal melanoma is a rare condition with an estimated incidence of about 0.3/10 lac per year and has a slight female predominance. …”
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“…SIMPLE SUMMARY: Cutaneous Melanoma (CM), arising from pigment-producing melanocytes in the skin, is an aggressive cancer with high metastatic potential. …”
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“…SIMPLE SUMMARY: Melanoma is a very aggressive and fatal malignant tumor. …”
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“…A subtype of malignant melanomas, nodular melanoma often carries a poor prognosis because of local invasion and frequent distant metastasis. …”
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“…The current staging system for melanoma is based on the 8(th) edition of TNM classification issued by the American Joint Committee on Cancer (AJCC) in 2017. …”
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“…The introduction in clinical practice of new drug compounds both targeted therapies anti-BRAF and checkpoint inhibitors have largely improved our potential to manage advanced metastatic melanoma patients. This has led to a significant improvement in terms of response rates and particularly in the overall survival (OS). …”
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“…Malignant melanoma is the most aggressive form of skin cancer, which originates from the malignant transformation of melanocytes, the melanin-producing cells of the skin. …”
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“…Melanoma develops as a result of several genetic alterations, with UV radiation often acting as a mutagenic risk factor. …”
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“…SIMPLE SUMMARY: The non-surgical treatment of cutaneous and/or subcutaneous melanoma lesions involves a multitude of local treatments, including radiotherapy. …”
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“…Sex-specific differences in melanoma tumor behavior have been described, and melanoma pathogenesis may be hormonally mediated. …”
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“…Malignant melanoma of the breast (MMB) is a rare disease that accounts for 3–5% of all melanomas. …”
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