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581por Krishna Mohan, M.V.T., Rajappa, Senthil J., Reddy, T. Vamshidhar, Paul, T. Roshni“…Malignant melanoma is rare in India; melanoma presenting as a metastatic disease with an unknown primary, involving the gastrointestinal tract without involving lymph nodes is extremely uncommon. …”
Publicado 2009
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582“…PURPOSE: To report a patient with small juxtapapillary choroidal melanoma with chromosome 3 monosomy treated with I(125) plaque and transpupillary thermotherapy (TTT). …”
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583por Caballero, Otavia L., Zhao, Qi, Rimoldi, Donata, Stevenson, Brian J., Svobodová, Suzanne, Devalle, Sylvie, Röhrig, Ute F., Pagotto, Anna, Michielin, Olivier, Speiser, Daniel, Wolchok, Jedd D., Liu, Cailian, Pejovic, Tanja, Odunsi, Kunle, Brasseur, Francis, Van den Eynde, Benoit J., Old, Lloyd J., Lu, Xin, Cebon, Jonathan, Strausberg, Robert L., Simpson, Andrew J.“…We found that melanoma cell lines from 37% of patients contained at least one mutated MAGE gene. …”
Publicado 2010
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584
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585“…Malignant melanoma is one of the most aggressive malignancies in human and is responsible for almost 60% of lethal skin tumors. …”
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586“…Early detection of lesions while minimising the unnecessary removal of benign lesions is the clinical aim in melanoma diagnosis. In this context, several non-invasive diagnostic modalities, such as dermoscopy, total body photography, and reflectance confocal microscopy have emerged in recent years aiming at increasing diagnostic accuracy. …”
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587“…THE INNER WORLD: An added dimension has now emerged—the impact on disease of the inner world, principally the numerous endogenous retroviruses (HERVs) within the human genome. Taking melanoma as an example, we propose a framework for understanding how a complex infectious and immunological background can induce or inhibit expression of a HERV-related disease process. …”
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588
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589por Favero, Giovani M, F Otuki, Michel, Oliveira, Karen A, Bohatch, Milton S, Borelli, Primavera, Barros, Francisco E, Maria, Durvanei A, Fernandes, Daniel, Bydlowski, Sergio P“…The aim of this study was evaluate the anti-tumoral activity of simvastatin in a B16F10 melanoma-mouse model. METHODS: Melanoma cells were treated with different concentrations of simvastatin and assessed by viability methods. …”
Publicado 2010
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590por Vidwans, Smruti J., Flaherty, Keith T., Fisher, David E., Tenenbaum, Jay M., Travers, Michael D., Shrager, Jeff“…While advanced melanoma remains one of the most challenging cancers, recent developments in our understanding of the molecular drivers of this disease have uncovered exciting opportunities to guide personalized therapeutic decisions. …”
Publicado 2011
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591por Uehara, Jiro, Ito, Yasuhiro, Takahashi, Ichiro, Honma, Masaru, Ishida-Yamamoto, Akemi, Matsuo, Shinobu, Iizuka, Hajime“…One month after the operation, a second melanoma lesion was noticed adjacent to the grafted site. …”
Publicado 2010
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592“…Our patient was unique in its massive size and clinical resemblance with malignant melanoma. The diagnosis was confirmed by dermoscopy and skin biopsy.…”
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593por Moreira, Rafaela Nogueira, Santos, Cassio Roberto Rocha, Lima, Nadia Lages, Verli, Flaviana Dornela, Marinho, Sandra Aparecida“…Melanomas are malignant lesions stemming from the disorganized proliferation of melanocytes. …”
Publicado 2010
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594por Dudley, Mark E.“…This report summarizes clinical trial results from the Surgery Branch, NCI, investigating tumor infiltrating lymphocytes (TIL) and gene engineered peripheral blood T cells for the therapy of patients with melanoma and other solid tumors.…”
Publicado 2011
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595“…Therefore, this review aims to discuss new findings about miRNAs in melanoma fields, underlying epigenetic processes, and also to argue possibilities of using miRNAs in melanoma diagnosis and therapy.…”
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596“…The recent RAF inhibitor trial with PLX4032/RG7204 in late-stage mutant B-RAF melanoma patients has been lauded as a success story for personalized cancer therapy since short-term clinical responses were observed in the majority patients. …”
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597“…The proliferative effects of the MAPK pathway may be complemented by the antiapoptotic signals of the PI3K/AKT pathway. After skin, melanoma most commonly affects the eye. Data for the constitutive activation of the MAPK pathway in uveal melanoma exists as well, however, not through mutations of RAS and RAF. …”
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598por Yi, Na-young, Park, Shin-ae, Park, Soo-won, Jeong, Man-bok, Kang, Min-soo, Jung, Joo-hyun, Choi, Min-cheol, Kim, Dae-yong, Nam, Tchi-chou, Seo, Kang-moon“…A histologic diagnosis of malignant uveal melanoma was made.…”
Publicado 2006
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599“…BACKGROUND: The prognosis of melanoma metastasized to other organs is very poor. …”
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600por Crocetti, Emanuele, Buzzoni, Carlotta, Chiarugi, Alessandra, Nardini, Paolo, Pimpinelli, Nicola“…Evaluate the ecological relationship between skin melanoma epidemiology and latitude in Italy. Methods. …”
Publicado 2012
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