-
721
-
722“…Recent advances have allowed the use of valuable archived patient tissue samples in proteomic research, resulting in an opportunity to perform cutting edge translational research. The field of melanoma research stands to benefit greatly from collaboration between dermatopathologists and proteomic scientists. …”
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
723
-
724por van Poppelen, Natasha M., Yavuzyigitoglu, Serdar, Smit, Kyra N., Vaarwater, Jolanda, Eussen, Bert, Brands, Tom, Paridaens, Dion, Kiliç, Emine, de Klein, Annelies“…Uveal melanoma (UM) is the most common primary intraocular malignancy in the Western world. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
725“…The diagnosis of primary malignant melanoma of the anorectum is extremely rare and carries a very poor prognosis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
726por Richtig, Erika“…The 2018 ASCO Annual Meeting provided a closer look on the details of studies already presented. In melanoma, the interest was on neoadjuvant treatment options with high pathological response rates as well as updates on large phase III studies in stage IV disease. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
727“…The patient underwent 3 mm punch biopsies, then digital amputation of the finger with pathology-proven melanoma. Histopathology investigation demonstrated three melanoma in situ and one invasive melanoma with a Breslow thickness of 1 mm. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
728“…Melanoma has several clinically and pathologically distinguishable subtypes, which also differ genetically. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
729por Rossi, Mariarita, Pellegrini, Cristina, Cardelli, Ludovica, Ciciarelli, Valeria, Di Nardo, Lucia, Fargnoli, Maria Concetta“…BACKGROUND: An estimated 5%–10% of all cutaneous melanoma cases occur in families. This review describes susceptibility genes currently known to be involved in melanoma predisposition, genetic testing of familial melanoma patients, and management implications. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
730
-
731por Vasilovici, Alina F., Grigore, Lavinia Elena, Ungureanu, Loredana, Fechete, Oana, Candrea, Elisabeta, Trifa, Adrian P., Vișan, Simona, Șenilă, Simona, Cosgarea, Rodica“…Melanoma represents the most aggressive skin cancer, with an unpredictable and often treatment resistant behavior. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
732por Paz, Helicia, Tsoi, Jennifer, Kalbasi, Anusha, Grasso, Catherine S., McBride, William H., Schaue, Dörthe, Butterfield, Lisa H., Maurer, Deena M., Ribas, Antoni, Graeber, Thomas G., Economou, James S.“…BACKGROUND: Various proinflammatory cytokines can be detected within the melanoma tumor microenvironment. Interleukin 32 (IL32) is produced by T cells, NK cells and monocytes/macrophages, but also by a subset of melanoma cells. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
733por Rueegg, Corina S., Stenehjem, Jo S., Egger, Matthias, Ghiasvand, Reza, Cho, Eunyoung, Lund, Eiliv, Weiderpass, Elisabete, Green, Adele C., Veierød, Marit B.“…Whether sunscreen use affects melanoma risk has been widely studied with contradictory results. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
734“…(1) Despite many years of research, melanoma still remains a big challenge for modern medicine. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
735“…Melanoma incidence is increasing and is associated with the majority of skin cancer–related deaths. …”
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
736“…Tumour metastasis is a multistep process. Melanoma is a highly aggressive cancer and metastasis accounts for the majority of patient deaths. microRNAs (miRNAs) are non-coding RNAs that affect the expression of their target genes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
737“…Vemurafenib was the first specific kinase inhibitor approved for therapy of advanced melanomas harboring BRAF-activating mutations, followed by dabrafenib and encorafenib. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
738por Ding, Ling-Wen, Sun, Qiao-Yang, Edwards, Jarem J., Fernández, Lucia Torres, Ran, Xue-Bin, Zhou, Si-Qin, Scolyer, Richard A., Wilmott, James S., Thompson, John F., Doan, Ngan, Said, Jonathan W., Venkatachalam, Nachiyappan, Xiao, Jin-Fen, Loh, Xin-Yi, Pein, Maren, Xu, Liang, Mullins, David W., Yang, Henry, Lin, De-Chen, Koeffler, H. Phillip“…We found that LNK is significantly elevated in cutaneous melanoma; this elevation is correlated with hyperactive signaling of the RAS-RAF-MEK pathway. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
739por Valko-Rokytovská, Marcela, Hubková, Beáta, Birková, Anna, Mašlanková, Jana, Stupák, Marek, Zábavníková, Marianna, Čižmárová, Beáta, Mareková, Mária“…Background and objectives: Melanin, which has a confirmed role in melanoma cell behaviour, is formed in the process of melanogenesis and is synthesized from tryptophan, L-tyrosine and their metabolites. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
740por Couto, Gabriela Klein, Segatto, Natália Vieira, Oliveira, Thaís Larré, Seixas, Fabiana Kömmling, Schachtschneider, Kyle M., Collares, Tiago“…The aim of this review is to evaluate how the screening of drugs and compounds for melanoma has been performed over the last seven decades. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto