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861por Hristova, Denitsa M., Fukumoto, Takeshi, Takemori, Chihiro, Gao, Le, Hua, Xia, Wang, Joshua X., Li, Ling, Beqiri, Marilda, Watters, Andrea, Vultur, Adina, Gimie, Yusra, Rebecca, Vito, Samarkina, Anastasia, Jimbo, Haruki, Nishigori, Chikako, Zhang, Jie, Cheng, Chaoran, Wei, Zhi, Somasundaram, Rajasekharan, Fukunaga-Kalabis, Mizuho, Herlyn, Meenhard“…The upregulation of the adaptor protein NUMB triggers melanocytic differentiation from multipotent skin stem cells, which share many properties with aggressive melanoma cells. Although NUMB acts as a tumor suppressor in various human cancer types, little is known about its role in melanoma. …”
Publicado 2022
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862“…Melanoma aggressiveness relies both on high intratumoral heterogeneity and on the capability of melanoma cells to switch among different differentiation phenotypes. …”
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863por Goto, Hiroyuki, Yoshida, Yuichi, Suyama, Hisashi, Shindo, Masahisa, Miwa, Ken, Nakamura, Hiroshige, Yamamoto, OsamuEnlace del recurso
Publicado 2022
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864“…PURPOSE: Malignant melanomas of the conjunctiva are extremely rare in children. …”
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865por Zemba, Mihail, Dumitrescu, Otilia-Maria, Gheorghe, Alina Gabriela, Radu, Madalina, Ionescu, Mihai Alexandru, Vatafu, Andrei, Dinu, Valentin“…SIMPLE SUMMARY: Radiation therapy, comprising brachytherapy, proton beam therapy, stereotactic radiotherapy, and radiosurgery, is the most used eye-sparing treatment for uveal melanoma worldwide. However, radiotherapy is associated with many complications, some of which are vision-threatening. …”
Publicado 2023
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866“…Choroidal melanoma is a rare malignant tumour, yet it is the most common primary intra-ocular neoplasm and second on the list of top ten most malignant melanoma sites in the body. …”
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867por Soares Santos, Daniela Filipa, Costa, Marta, Carvalho, Patrícia, Santos, Rui M., Carvalho, ArmandoEnlace del recurso
Publicado 2021
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869por Barbagallo, Cristina, Stella, Michele, Broggi, Giuseppe, Russo, Andrea, Caltabiano, Rosario, Ragusa, Marco“…SIMPLE SUMMARY: Uveal melanoma (UM) is a rare eye cancer with a high mortality rate due to metastases, leading to death in up to 50% of patients within 10 years from UM diagnosis. …”
Publicado 2023
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870“…OBJECTIVES: Are twofold: 1) to estimate the relationship between obesity (BMI ≥30) and the prevalence of melanoma in different US states and 2) to examine the possibility of defining a new risk group. …”
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871por (Jitian) Mihulecea, Cristina-Raluca, Iancu, Gabriela Mariana, Leventer, Mihaela, Rotaru, Maria“…The gold standard for melanoma diagnosis is histopathological examination, but dermoscopy is also very important for its detection. …”
Publicado 2023
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872por Allard-Coutu, Alexandra, Dobson, Victoria, Schmitz, Erika, Shah, Hely, Nessim, Carolyn“…The growing repertoire of approved immune-checkpoint inhibitors and targeted therapy has revolutionized the adjuvant treatment of melanoma. While the treatment of primary cutaneous melanoma remains wide local excision (WLE), the management of regional lymph nodes continues to evolve in light of practice-changing clinical trials and dramatically improved adjuvant therapy. …”
Publicado 2023
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873por Kamińska, Paula, Buszka, Karolina, Galus, Łukasz, Jankowski, Maurycy, Nowicki, Michał, Mackiewicz, Jacek, Kaczmarek, Mariusz, Budna-Tukan, Joanna“…Despite the rising public awareness of the risk factors and the possible prevention of melanoma development, it remains challenging in terms of diagnosis and treatment. …”
Publicado 2023
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874por Velayutham, Sadeeshkumar, Seerattan, Ryan, Sultan, Maab, Seal, Trisha, Danthurthy, Samaya, Chinnappan, Baskaran, Landi, Jessica, Pearl, Kaitlyn, Singh, Aveta, Smalley, Keiran S. M., Zaias, Julia, Choi, Jun Yong, Minond, Dmitriy“…Despite the successes of immunotherapy, melanoma remains one of the deadliest cancers, therefore, the need for innovation remains high. …”
Publicado 2023
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876por Johnston, Leah, Starkey, Samantha, Mukovozov, Ilya, Robertson, Lynne, Petrella, Teresa, Alhusayen, Raed“…INTRODUCTION: Cutaneous melanoma accounts for more than 70% of all skin cancer deaths. …”
Publicado 2023
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877“…For the past 20 years thickness of the primary tumour has been accepted as the most important guide to prognosis for patients with primary cutaneous malignant melanoma. The changing epidemiology of melanoma with an increasing number of patients with thin tumours has necessitated a reappraisal of this, with particular reference to interactions among tumour thickness, the patients' sex and the presence or absence of ulceration of the primary tumour. …”
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878A unique antigenic epitope of human melanoma is carried on the common melanoma glycoprotein gp95/p97Publicado 1989“…Analysis of antibodies present in the serum of melanoma patient FD has shown that they detect a unique tumor epitope present only on the autologous melanoma cell line SK-MEL-131. …”
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879por Guba, M, Bosserhoff, A-K, Steinbauer, M, Abels, C, Anthuber, M, Buettner, R, Jauch, K-W“…The secreted MIA protein is strongly expressed by advanced primary and metastatic melanomas but not in normal melanocytes. Previous studies have shown that MIA serum levels correlate with clinical tumour progression in melanoma patients. …”
Publicado 2000
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880por Langezaal, S M, Graadt van Roggen, J F, Cleton-Jansen, A M, Baelde, J J, Hogendoorn, P C W“…Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft parts) and conventional malignant melanoma may demonstrate significant morphologic overlap at the light microscopic and ultrastructural level. …”
Publicado 2001
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