Mostrando 861 - 880 Resultados de 27,972 Para Buscar '"melanoma"', tiempo de consulta: 0.29s Limitar resultados
  1. 861
    “…The upregulation of the adaptor protein NUMB triggers melanocytic differentiation from multipotent skin stem cells, which share many properties with aggressive melanoma cells. Although NUMB acts as a tumor suppressor in various human cancer types, little is known about its role in melanoma. …”
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  2. 862
    “…Melanoma aggressiveness relies both on high intratumoral heterogeneity and on the capability of melanoma cells to switch among different differentiation phenotypes. …”
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  3. 863
  4. 864
    “…PURPOSE: Malignant melanomas of the conjunctiva are extremely rare in children. …”
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  5. 865
    “…SIMPLE SUMMARY: Radiation therapy, comprising brachytherapy, proton beam therapy, stereotactic radiotherapy, and radiosurgery, is the most used eye-sparing treatment for uveal melanoma worldwide. However, radiotherapy is associated with many complications, some of which are vision-threatening. …”
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  6. 866
    “…Choroidal melanoma is a rare malignant tumour, yet it is the most common primary intra-ocular neoplasm and second on the list of top ten most malignant melanoma sites in the body. …”
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  7. 867
  8. 868
  9. 869
    “…SIMPLE SUMMARY: Uveal melanoma (UM) is a rare eye cancer with a high mortality rate due to metastases, leading to death in up to 50% of patients within 10 years from UM diagnosis. …”
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  10. 870
    “…OBJECTIVES: Are twofold: 1) to estimate the relationship between obesity (BMI ≥30) and the prevalence of melanoma in different US states and 2) to examine the possibility of defining a new risk group. …”
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  11. 871
    “…The gold standard for melanoma diagnosis is histopathological examination, but dermoscopy is also very important for its detection. …”
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  12. 872
    “…The growing repertoire of approved immune-checkpoint inhibitors and targeted therapy has revolutionized the adjuvant treatment of melanoma. While the treatment of primary cutaneous melanoma remains wide local excision (WLE), the management of regional lymph nodes continues to evolve in light of practice-changing clinical trials and dramatically improved adjuvant therapy. …”
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  13. 873
    “…Despite the rising public awareness of the risk factors and the possible prevention of melanoma development, it remains challenging in terms of diagnosis and treatment. …”
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  14. 874
  15. 875
  16. 876
  17. 877
    “…For the past 20 years thickness of the primary tumour has been accepted as the most important guide to prognosis for patients with primary cutaneous malignant melanoma. The changing epidemiology of melanoma with an increasing number of patients with thin tumours has necessitated a reappraisal of this, with particular reference to interactions among tumour thickness, the patients' sex and the presence or absence of ulceration of the primary tumour. …”
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  18. 878
    Publicado 1989
    “…Analysis of antibodies present in the serum of melanoma patient FD has shown that they detect a unique tumor epitope present only on the autologous melanoma cell line SK-MEL-131. …”
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  19. 879
    “…The secreted MIA protein is strongly expressed by advanced primary and metastatic melanomas but not in normal melanocytes. Previous studies have shown that MIA serum levels correlate with clinical tumour progression in melanoma patients. …”
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  20. 880
    “…Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft parts) and conventional malignant melanoma may demonstrate significant morphologic overlap at the light microscopic and ultrastructural level. …”
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