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921por Kähler, Katharina C., Hüning, S., Nashan, D., Meiss, F., Rafei-Shamsabadi, D. A., Rissmann, H., Colapietro, C., Livingstone, E., Maul, L. V., Heppt, M., Hassel, J. C., Gutzmer, R., Loquai, C., Heinzerling, L., Sachse, M. M., Bohne, A. S., Moysig, L., Peters, W., Rusch, J., Blome, C.“…METHODS: In this study (“GERMELATOX-A”), 136 low-risk melanoma patients from 11 skin cancer centers were asked to rate side effect scenarios typical for each (c)ICI and TT with mild-to-moderate or severe toxicity and melanoma recurrence leading to cancer death. …”
Publicado 2023
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922“…Topical imiquimod may be a therapeutic option for the treatment of melanoma in situ and lentigo maligna melanoma due to its efficacy, tolerability, and non-invasiveness. …”
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923“…The frequency of the phenotypes of this isoenzyme in melanoma (MM) patients (n = 197) is reported here. …”
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924por Tilman, Gaëlle, Mattiussi, Marina, Brasseur, Francis, van Baren, Nicolas, Decottignies, Anabelle“…POSTN is not expressed in blood cancers. In melanoma samples, average periostin expression is not increased in primary tumors whereas POSTN overexpression was detected in about 60% of melanoma metastatic tumors in the liver or lymph nodes. …”
Publicado 2007
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925por Autier, P., Doré, J. F., Gefeller, O., Cesarini, J. P., Lejeune, F., Koelmel, K. F., Lienard, D., Kleeberg, U. R.“…Melanoma risk among subjects from Germany, France and Belgium who had lived for 1 year or more in sunny climates was examined in a one-to-one unmatched case-control study conducted among white subjects 20 years old or more. …”
Publicado 1997
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926por van der Velden, Haike M. J., van Rossum, Michelle M., Blokx, Willeke A. M., Boezeman, Jan B. M., Gerritsen, Marie-Jeanne P.“…The increasing number of living cutaneous melanoma patients and the increased risk of developing a second primary tumour incited us to analyse the clinical characteristics of cutaneous melanoma and define the frequency, site, and type of second primary cancers in cutaneous melanoma patients. …”
Publicado 2009
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927por Ribas, Antoni, Camacho, Luis H, Lee, Sun Min, Hersh, Evan M, Brown, Charles K, Richards, Jon M, Rodriguez, Maria Jovie, Prieto, Victor G, Glaspy, John A, Oseguera, Denise K, Hernandez, Jackie, Villanueva, Arturo, Chmielowski, Bartosz, Mitsky, Peggie, Bercovici, Nadège, Wasserman, Ernesto, Landais, Didier, Ross, Merrick I“…BACKGROUND: Several single center studies have provided evidence of immune activation and antitumor activity of therapeutic vaccination with dendritic cells (DC) in patients with metastatic melanoma. The efficacy of this approach in patients with favorable prognosis metastatic melanoma limited to the skin, subcutaneous tissues and lung (stages IIIc, M1a, M1b) was tested in a multicenter two stage phase 2 study with centralized DC manufacturing. …”
Publicado 2010
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928por Fazakas, Csilla, Wilhelm, Imola, Nagyőszi, Péter, Farkas, Attila E., Haskó, János, Molnár, Judit, Bauer, Hannelore, Bauer, Hans-Christian, Ayaydin, Ferhan, Dung, Ngo Thi Khue, Siklós, László, Krizbai, István A.“…Malignant melanoma represents the third common cause of brain metastasis, having the highest propensity to metastasize to the brain of all primary neoplasms in adults. …”
Publicado 2011
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929por Oh, Tae Seok, Bae, Eui Jong, Ro, Ki Woong, Seo, Soo Hong, Son, Sang Wook, Kim, Il-Hwan“…Clinical guidelines suggest that suspicious pigmented lesions of the plantar or palmar area require biopsy for early detection of acral melanoma. We present here a case of acral lentiginous melanoma in which various melanocytic atypia was observed at each biopsy site, including focal melanocytic proliferation. …”
Publicado 2011
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930por Lee, Sangsin, Lee, Hyo-Jin, Oh, Sang-Ha, Im, Myung, Lee, Jeung-Hoon, Seo, Young-Joon, Lee, Young“…Although more than 90% of melanomas have cutaneous origins, melanomas sometimes present metastatically with no apparent primary lesion. …”
Publicado 2011
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931por Mei, Han-fang, Jin, Xiao-bao, Zhu, Jia-yong, Zeng, Ai-hua, Wu, Qiang, Lu, Xue-mei, Li, Xiao-bo, Shen, Juan“…Therefore, β-defensin 2 may be used for the development of immunotherapy for the intervention of melanoma.…”
Publicado 2012
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932por Schäfer, Annika, Emmert, Steffen, Kruppa, Jochen, Schubert, Steffen, Tzvetkov, Mladen, Mössner, Rotraut, Reich, Kristian, Berking, Carola, Volkenandt, Matthias, Pföhler, Claudia, Schön, Michael P., Vogt, Thomas, König, Inke R., Reichrath, Jörg“…Melanoma is one of the most aggressive human cancers. …”
Publicado 2012
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933por Charfi, Slim, Ellouze, Sameh, Mnif, Hela, Amouri, Ali, Khabir, Abdelmajid, Sellami-Boudawara, Tahya“…Plasmacytoid variant of melanoma is reported in only rare cases. We present the case of a 54-years-old man admitted for enlarged lymph nodes in the lumbar region. …”
Publicado 2012
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934por Saladi, Srinivas V, Wong, Philip G, Trivedi, Archit R, Marathe, Himangi G, Keenen, Bridget, Aras, Shweta, Liew, Zi-Qi, Setaluri, Vijayasaradhi, de la Serna, Ivana L“…We determined that the catalytic subunit, BRG1, of the SWI/SNF complex protects melanoma cells against UV-induced death. BRG1 prevents apoptosis in UV-irradiated melanoma cells by activating expression of the melanoma inhibitor of apoptosis (ML-IAP). …”
Publicado 2013
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935por Lin, Bi-wen, Jiao, Ze-long, Fan, Jian-feng, Peng, Liang, Li, Lei, Zhao, Zi-gang, Ding, Xiang-yu, Li, Heng-jin“…The acquisition of metastasis potential is a critical point for malignant tumors. Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24) is a potential tumor suppress gene and frequently down-regulated in malignant tumors. …”
Publicado 2013
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936por Trevarton, Alexander J., Mann, Michael B., Knapp, Christoph, Araki, Hiromitsu, Wren, Jonathan D., Stones-Havas, Steven, Black, Michael A., Print, Cristin G.“…Despite on-going research, metastatic melanoma survival rates remain low and treatment options are limited. …”
Publicado 2013
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937“…BACKGROUND: New Zealand and Australia have the highest incidence and mortality rates from cutaneous melanoma in the world. The predominantly fair-skinned New Zealanders and Australians both enjoy sun, tanned skin and the outdoors, and differences in these activities among generations have been important determinants of trends in melanoma mortality. …”
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938por Garay, Tamás, Kenessey, István, Molnár, Eszter, Juhász, Éva, Réti, Andrea, László, Viktória, Rózsás, Anita, Dobos, Judit, Döme, Balázs, Berger, Walter, Klepetko, Walter, Tóvári, József, Tímár, József, Hegedűs, Balázs“…While targeted therapy brought a new era in the treatment of BRAF mutant melanoma, therapeutic options for non-BRAF mutant cases are still limited. …”
Publicado 2015
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939por Mukherjee, Nabanita, Reuland, Steven N., Lu, Yan, Luo, Yuchun, Lambert, Karoline, Fujita, Mayumi, Robinson, William A, Robinson, Steven E, Norris, David A., Shellman, Yiqun G.“…Investigations from multiple laboratories support the existence of melanoma initiating cells (MICs) that potentially contribute to melanoma's drug resistance. …”
Publicado 2014
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940“…BACKGROUND: Oral malignant melanoma (OMM) is an aggressive tumor with very low survival rate and easy to metastasize. …”
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