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1041por Coleman, Christina, Levine, Danielle, Kishore, Raj, Qin, Gangjian, Thorne, Tina, Lambers, Erin, Sasi, Sharath P., Yaar, Mina, Gilchrest, Barbara A., Goukassian, David A.“…We found that T-oligo-treated human melanoma (MM-AN) cells had decreased expression of vascular endothelial growth factor (VEGF), VEGF receptor 2, angiopoeitin-1 and -2 and decreased VEGF secretion. …”
Publicado 2010
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1042“…We report a case of pulmonary malignant melanoma as a late metastatic manifestation of primary plantar malignant melanoma in a 61-year-old man who presented with hemoptysis; metastatic malignant melanoma of the lung occurred 12 years after resection of primary malignant melanoma of sole of the right foot.…”
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1043por Rahmah, Nunung Nur, Horiuchi, Tetsuyoshi, Nakayama, Jun, Nitta, Junpei, Hongo, Kazuhiro“…BACKGROUND: The authors report a rare case of a patient with previously treated cutaneous malignant melanoma that recurred 1 year later as an intracranial meningioma. …”
Publicado 2010
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1044por Caballero, Otavia L., Zhao, Qi, Rimoldi, Donata, Stevenson, Brian J., Svobodová, Suzanne, Devalle, Sylvie, Röhrig, Ute F., Pagotto, Anna, Michielin, Olivier, Speiser, Daniel, Wolchok, Jedd D., Liu, Cailian, Pejovic, Tanja, Odunsi, Kunle, Brasseur, Francis, Van den Eynde, Benoit J., Old, Lloyd J., Lu, Xin, Cebon, Jonathan, Strausberg, Robert L., Simpson, Andrew J.Enlace del recurso
Publicado 2010
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1045“…Adoptive Cell Transfer (ACT) of Tumor-Infiltrating Lymphocytes (TIL) in combination with lymphodepletion has proven to be an effective treatment for metastatic melanoma patients, with an objective response rate in 50%–70% of the patients. …”
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1046“…BACKGROUND: Melanomas within the alimentary tract are usually metastatic in origin. …”
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1047“…Herein reported is a case of congenital malignant melanoma in a premature male baby from a 25-year-old healthy mother who was found to have hydramnios at the 29th week of gestation. …”
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1048“…Identification of key enzymes regulating melanoma progression and drug resistance has the potential to lead to the development of novel, more effective targeted agents for inhibiting this deadly form of skin cancer. …”
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1049“…Melanoma metastatic to the appendix is extremely rare. …”
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1050por Flaherty, Keith T.“…Melanoma is among the leading causes of years of life lost due to cancer. …”
Publicado 2011
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1051“…Three hundred twenty-seven subjects with incident melanoma and 119 melanoma-free controls completed a structured interview assessing melanoma risk factors. …”
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1052por Chang, Gwendolen Y, Kohrt, Holbrook E, Stuge, Tor B, Schwartz, Erich J, Weber, Jeffrey S, Lee, Peter P“…BACKGROUND: Vitiligo is a common toxicity associated with immunotherapy for melanoma. Cytotoxic T lymphocytes (CTLs) against melanoma commonly target melanoma-associated antigens (MAAs) which are also expressed by melanocytes. …”
Publicado 2011
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1053por Udayakumar, Durga, Zhang, Guoqi, Ji, Zhenyu, Njauw, Ching-Ni, Mroz, Pawel, Tsao, Hensin“…To functionally clarify EphA2’s role in melanoma, we analyzed a panel of melanoma cell lines and found that EphA2 levels are elevated in a significant fraction of the samples. …”
Publicado 2011
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1054“…The incidence of malignant melanoma, the most dangerous form of skin cancer, is rising each year. …”
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1055por Godar, Dianne E.“…The incidence of cutaneous malignant melanoma (CMM) has been increasing at a steady rate in fair-skinned populations around the world for decades. …”
Publicado 2011
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1056“…We report a case of a giant melanoma on the back with a very extreme Breslow thickness. …”
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1057por Poliseno, Laura, Haimovic, Adele, Christos, Paul J., Vega y Saenz de Miera, Eleazar C., Shapiro, Richard, Pavlick, Anna, Berman, Russell S., Darvishian, Farbod, Osman, ImanEnlace del recurso
Publicado 2011
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1058“…Recently, advances have been made which are revolutionizing the standard of care for patients with BRAF mutant melanoma. This paper provides an overview on the pathogenic ramifications of mutant BRAF signaling, the latest molecular testing methods to detect BRAF mutations, and the most recent clinical data of BRAF pathway inhibitors in patients with melanoma and BRAF mutations. …”
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1059“…Recent technological advances in cancer genomics make it possible to dissect complicated genomic aberrations of melanomas. In particular, several specific genomic aberrations including 11q13 amplification and KIT aberrations have been identified in acral melanomas. …”
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1060“…The examination of the phenotypic and (epi) genetic changes in cutaneous melanoma has identified several genes deemed central to the development and progression of melanoma. …”
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