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  1. 1141
    “…Immune therapy has provided a significant breakthrough in the treatment of metastatic melanoma. Despite the remarkable clinical efficacy and established involvement of effector CD8 T cells, the knowledge of the exact peptide-MHC complexes recognized by T cells on the tumor cell surface is limited. …”
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    Broadening the repertoire of melanoma-associated T-cell epitopes
  2. 1142
    “…Most melanomas occur on the skin, but a small percentage of these life-threatening cancers affect other parts of the body, such as the eye and mucous membranes, including the mouth. …”
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    Cellular Mechanisms of Oxidative Stress and Action in Melanoma
  3. 1143
    “…In recent years, melanoma has become a poster-child for the development of oncogene-directed targeted therapies. …”
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    Beyond BRAF: where next for melanoma therapy?
  4. 1144
    por Graziani, Grazia, Lacal, Pedro M.
    Publicado 2015
    “…This review is focused on the role of NRP-1 in melanoma aggressiveness and on the evidence supporting its use as target of therapies for metastatic melanoma.…”
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    Neuropilin-1 as Therapeutic Target for Malignant Melanoma
  5. 1145
    “…We evaluated the BRAF-M% in melanomas, and the genetic causes of its variation. …”
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    Variations of BRAF mutant allele percentage in melanomas
  6. 1146
    “…Malignant melanoma occurs most frequently on the skin. However, it can also arise in other organs and tissues of the body. …”
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    Primary Pulmonary Malignant Melanoma: An Unexpected Tumor
  7. 1147
    “…Melanoma is known as an exceptionally aggressive and treatment-resistant human cancer. …”
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    Perspective of Targeting Cancer-Associated Fibroblasts in Melanoma
  8. 1148
    “…This is the first reported case of a melanoma developing in the red ink pigment of a multi-colored tattoo.…”
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    Malignant Melanoma Arising in Red Tattoo Ink
  9. 1149
    “…Overall survival rate was significantly better in nivolumab-treated melanoma patients than dacarbazine-treated melanoma patients. …”
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    Nivolumab in the treatment of malignant melanoma: review of the literature
  10. 1150
    “…In a recent study, we investigated the mechanism underlying calcium-mediated invasion and metastasis in melanoma and discovered that hyperactive Ca(2+) oscillation in melanoma cells enhanced invasion and metastasis by promoting invadopodium formation and extracellular matrix remodeling.…”
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    Disseminating melanoma cells surf on calcium waves
  11. 1151
    “…BACKGROUND: The dermoscopic criteria of extrafacial melanomas are well-known. OBJECTIVE: To determine the frequency of dermatoscopic findings in head and neck melanomas (HNM) and to assess the distinguishing dermoscopic criteria of facial and extrafacial melanoma. …”
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    Dermoscopic and clinical features of head and neck melanoma
  12. 1152
    por Chipuk, Jerry Edward
    Publicado 2015
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    BCL-2 proteins: melanoma lives on the edge
  13. 1153
    “…Melanoma is a malignant tumor rarely being described in sub-Saharan Africa. …”
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    Melanoma of the Right Foot Simulating Kaposi's Disease
  14. 1154
    “…Background: Malignant melanoma cells are known to have altered expression of genes supporting proliferation and invasion, however, the expression of molecules of the Netrin family of repellent factors has not been analyzed in melanomas until now. …”
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    Functional Implication of Netrin Expression in Malignant Melanoma
  15. 1155
    “…The development and progression of melanoma have been attributed to independent or combined genetic and epigenetic events. …”
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    Epigenetic regulation in human melanoma: past and future
  16. 1156
    por Barnhart, Carrie
    Publicado 2015
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    Pembrolizumab: First in Class for Treatment of Metastatic Melanoma
  17. 1157
    por Tsai, Katy K., Daud, Adil I.
    Publicado 2015
    “…Advanced melanoma has historically been a difficult disease to treat due to few effective systemic treatment options. …”
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    Nivolumab plus ipilimumab in the treatment of advanced melanoma
  18. 1158
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    TNF-R1, an immune checkpoint in melanoma?
  19. 1159
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    Molecular and immune heterogeneity in synchronous melanoma metastases
  20. 1160
    “…In particular, the treatment of melanoma, a deadly and fast-spreading form of skin cancer, has been transformed by these new targeted therapies. …”
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    Tailoring the Treatment of Melanoma: Implications for Personalized Medicine
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