Mostrando 101 - 120 Resultados de 27,972 Para Buscar '"melanoma"', tiempo de consulta: 0.62s Limitar resultados
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  10. 110
    Publicado 1987
    “…Phenotypic heterogeneity is a characteristic feature of tumor lesions in patients with melanoma. Variability can be observed in cell morphology, pigmentation, and antigen expression. …”
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  11. 111
    “…Cutaneous melanoma and uveal melanoma both derive from melanocytes but show remarkable differences in tumorigenesis, mode of metastatic spread, genetic alterations, and therapeutic response. …”
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  12. 112
    “…He had right ocular melanoma 23 years ago with subsequent enucleation which was the standard treatment at that time. …”
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  13. 113
    “…As a result, current melanoma staging and treatment guidelines are being challenged. …”
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  14. 114
    “…Genome-wide association studies (GWAS) and candidate pathway studies have identified low-penetrant genetic variants associated with cutaneous melanoma. We investigated the association of melanoma-risk variants with primary melanoma tumor prognostic characteristics and melanoma-specific survival. …”
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  15. 115
    “…A study of 953 invasive cutaneous malignant melanomas of the head and neck was performed to determine differences between lentigo maligna melanoma and other histogenetic types with regard to patients and sites affected; prognosis was analysed in 595 of these cases. …”
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  16. 116
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  18. 118
    Publicado 1982
    “…The characteristics of the normal melanocyte precursor have been inferred from the features of melanomas that express early markers of melanocyte differentiation. …”
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  19. 119
    “…BACKGROUND: Two high-risk genes have been implicated in the development of CM (cutaneous melanoma). Germline mutations of the CDKN2A gene are found in < 25% of melanoma-prone families and there are only seven families with mutation of the CDK4 gene reported to date. …”
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  20. 120
    “…The recent discovery of activating mutations in the BRAF gene in many cutaneous melanomas led us to screen the genomic sequence of BRAF exons 11 and 15 in a series of 48 intraocular (uveal) melanomas, together with control samples from three cutaneous melanomas and the SK-Mel-28 cell line, which has a BRAF mutation. …”
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