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1481por Poniewierska-Baran, Agata, Słuczanowska-Głąbowska, Sylwia, Małkowska, Paulina, Sierawska, Olga, Zadroga, Łukasz, Pawlik, Andrzej, Niedźwiedzka-Rystwej, Paulina“…Melanoma is one of the most aggressive and progressive skin cancers. …”
Publicado 2022
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1482por Zywicki, Alexsaundra, Zhang, Naixin, Sagan, Olivia, Moore, Richard, Rowswell-Turner, Rachael, Angel, Cynthia, DuBeshter, Brent, Numbere, Numbereye, Smith, Ashlee“…Pelvic metastasis of melanoma is extremely rare and may pose a diagnostic challenge. …”
Publicado 2023
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1483“…Melanoma is the most aggressive type of skin cancer, with a greater risk of metastasis and a higher prevalence and mortality rate. …”
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1484“…Here, we evaluate the increasing body of literature that argues the “double-edged” consequences of autophagy manipulation in cancer therapy, with a particular focus on highly plastic and mutagenic melanoma. We also discuss the caveats that must be considered when evaluating whether autophagy blockade is the effector mechanism of some anti-cancer therapy particularly associated with lysosomotropic agents. …”
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1485“…SIMPLE SUMMARY: Immunotherapy has demonstrated the ability to reduce the risk of recurrence for melanoma following surgical resection and improve survival in patients with unresectable disease. …”
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1486por Flynn, M. Seth, Robinson, Camille, Patel, Surya, Liu, Beiyu, Green, Cynthia, Pavlis, Michelle“…Patients with Parkinson disease (PD) are at high risk for developing melanoma, although current literature lacks details on the associated clinicopathologic characteristics. …”
Publicado 2022
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1487“…BACKGROUND: Patients with invasive melanoma are at increased risk of developing subsequent invasive melanoma, but the risks for those with primary in situ melanoma are unclear. …”
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1488“…Host immunogenetics play a critical role in the human immune response to melanoma, influencing both melanoma prevalence and immunotherapy outcomes. …”
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1489por Michielon, Elisabetta, López González, Marta, Stolk, Dorian A., Stolwijk, Joeke G. C., Roffel, Sanne, Waaijman, Taco, Lougheed, Sinéad M., de Gruijl, Tanja D., Gibbs, Susan“…SIMPLE SUMMARY: The melanoma-conditioned microenvironment promotes immune escape and tumor progression, contributing to resistance to anti-melanoma immunotherapy in a large group of treated patients. …”
Publicado 2023
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1490por Rok, Jakub, Kowalska, Justyna, Rzepka, Zuzanna, Stencel, Dominika, Skorek, Anna, Banach, Klaudia, Wrześniok, Dorota“…High mortality, aggressiveness, and the relatively low effectiveness of therapy make melanoma the most dangerous of skin cancers. Previously published studies presented the promising therapeutic potential of minocycline, doxycycline, and chlortetracycline on melanoma cells. …”
Publicado 2023
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1491por Romano, Benedetta, Maresca, Daniela Claudia, Somma, Fabio, Ahmadi, Peni, Putra, Masteria Yunovilsa, Rahmawati, Siti Irma, Chianese, Giuseppina, Formisano, Carmen, Ianaro, Angela, Ercolano, Giuseppe“…Here, we investigated, for the first time, the therapeutic effect of an extract (referred as iSP) from the sponge, Ircinia ramosa (Porifera, Dictyoceratida, and Irciniidae), on A375 human melanoma cells. We found that iSP impaired A375 melanoma cells proliferation, induced cell death through caspase-dependent apoptosis and arrested cells in the G1 phase of the cell cycle, as demonstrated via both flow cytometry and qPCR analysis. …”
Publicado 2023
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1492“…Urethral melanomas are a rare subtype of noncutaneous melanomas. …”
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1493“…The relationship between the melanoma cell cycle and macrophage DNA synthesis was studied with synchronous melanoma cells. …”
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1494por Gogas, H, Kefala, G, Bafaloukos, D, Frangia, K, Polyzos, A, Pectasides, D, Tsoutsos, D, Panagiotou, P, Ioannovich, J, Loukopoulos, D“…The purpose of this study was to address the prognostic significance of circulating melanoma cells by reverse transcriptase-polymerase chain reaction in the peripheral blood of stage IIB and III melanoma patients on high-dose adjuvant interferon at multiple sequential time points from initiation of treatment. …”
Publicado 2002
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1495por Sarrabayrouse, Guillaume, Pich, Christine, Moriez, Raphaël, Armand-Labit, Virginie, Rochaix, Philippe, Favre, Gilles, Tilkin-Mariamé, Anne-Françoise“…BACKGROUND: Suboptimal activation of T lymphocytes by melanoma cells is often due to the defective expression of class I major histocompatibility antigens (MHC-I) and costimulatory molecules. …”
Publicado 2010
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1496por de Bruyn, Marco, Rybczynska, Anna A, Wei, Yunwei, Schwenkert, Michael, Fey, Georg H, Dierckx, Rudi AJO, van Waarde, Aren, Helfrich, Wijnand, Bremer, Edwin“…BACKGROUND: Advanced melanoma is characterized by a pronounced resistance to therapy leading to a limited patient survival of ~6 - 9 months. …”
Publicado 2010
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1497por Labelle-Côté, Mélissa, Dusseault, Julie, Ismaïl, Salma, Picard-Cloutier, Aude, Siegel, Peter M, Larose, Louise“…Importantly, we uncovered that injection of Nck2-overexpressing human primary melanoma cells into mice increases melanoma-derived tumor growth rate. …”
Publicado 2011
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1498por Rychetnik, Lucie, Morton, Rachael L, McCaffery, Kirsten, Thompson, John F, Menzies, Scott W, Irwig, Les“…Shared care between melanoma specialists and general practitioners is an increasingly important approach to meeting the needs of a growing population of melanoma survivors. …”
Publicado 2012
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1499por Rexhepaj, Elton, Agnarsdóttir, Margrét, Bergman, Julia, Edqvist, Per-Henrik, Bergqvist, Michael, Uhlén, Mathias, Gallagher, William M., Lundberg, Emma, Ponten, Fredrik“…A support vector machine melanoma classification model was learned from a discovery melanoma patient cohort (n = 264) and subsequently validated on an independent cohort of melanoma patient tissue sample images (n = 157). …”
Publicado 2013
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1500por Ascierto, Paolo A, Grimaldi, Antonio M, Acquavella, Nicolas, Borgognoni, Lorenzo, Calabrò, Luana, Cascinelli, Natale, Cesano, Alessandra, Del Vecchio, Michele, Eggermont, Alexander M, Faries, Mark, Ferrone, Soldano, Fox, Bernard A, Gajewski, Thomas F, Galon, Jérôme, Gnjatic, Sacha, Gogas, Helen, Kashani-Sabet, Mohammed, Kaufman, Howard L, Larkin, James, Lo, Roger S, Mantovani, Alberto, Margolin, Kim, Melief, Cornelis, McArthur, Grant, Palmieri, Giuseppe, Puzanov, Igor, Ribas, Antoni, Seliger, Barbara, Sosman, Jeff, Suenaert, Peter, Tarhini, Ahmad A, Trinchieri, Giorgio, Vidal-Vanaclocha, Fernando, Wang, Ena, Ciliberto, Gennaro, Mozzillo, Nicola, Marincola, Francesco M, Thurin, Magdalena“…Recent insights into the genetic and somatic aberrations have initiated a new era of rapidly evolving targeted and immune-based treatments for melanoma. After decades of unsuccessful attempts to finding a more effective cure in the treatment of melanoma now we have several drugs active in melanoma. …”
Publicado 2013
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