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146“…The American Joint Committee on Cancer (AJCC) staging of cutaneous melanoma is a continuously evolving system. The identification of increasingly more accurate prognostic factors has led to major changes in melanoma staging over the years, and the current system described in this review will likely be modified in the near future. …”
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147por Palmieri, Giuseppe, Capone, Mariaelena, Ascierto, Maria Libera, Gentilcore, Giusy, Stroncek, David F, Casula, Milena, Sini, Maria Cristina, Palla, Marco, Mozzillo, Nicola, Ascierto, Paolo A“…The characterization of the molecular mechanisms involved in development and progression of melanoma could be helpful to identify the molecular profiles underlying aggressiveness, clinical behavior, and response to therapy as well as to better classify the subsets of melanoma patients with different prognosis and/or clinical outcome. …”
Publicado 2009
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148“…Malignant melanoma is a highly lethal disease unless detected early. …”
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151“…With an incidence that is increasing at 2–5% per year, cutaneous melanoma is an international scourge that disproportionately targets young individuals. …”
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153“…Melanoma is a malignant tumor that can affect any area of the anatomical economy. …”
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154
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155“…The behavior of head and neck melanoma is aggressive, and it has an overall poorer prognosis than that of other skin sites. …”
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156por Mun, Goo-HyunEnlace del recurso
Publicado 2012
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159“…Melanomas represent 4% of all malignant tumors of the skin, yet account for 80% of deaths from skin cancer.While in the early stages patients can be successfully treated with surgical resection, metastatic melanoma prognosis is dismal. …”
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160“…Primary rectal melanoma is rare and only represents up to 4% of anorectal malignancies. …”
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