“…SIMPLE SUMMARY: Our study looked at the usefulness of a protein called S100 in monitoring the progression of uveal melanoma, a type of black skin cancer first growing in the eye. …”
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“…Nail apparatus melanoma (NAM) is a rare type of cutaneous melanoma that belongs to the acral melanoma subtype. …”
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“…However, the function of Axl in the invasion and metastasis of melanoma, the most lethal skin cancer, remains largely unknown. …”
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“…An association with vulval (Vu) and penile (Pe) squamous carcinoma (SCC) is now well established but melanoma (MM) has only rarely been reported complicating GLSc. …”
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“…In this review, we analyze the treatment approaches as well as unique features observed in melanoma patients who develop cutaneous immune-related adverse events. …”
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“…PRAME (PReferentially expressed Antigen in MElanoma), a cancer-testis antigen expressed in normal and neoplastic tissues with several functions, proved to be a useful diagnostic tool in the differential diagnosis between benign and malignant melanocytic lesions. …”
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“…Mucosal malignant melanoma arising from the head and neck region is a rare entity, and it is more aggressive than cutaneous melanoma. …”
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“…Non-melanoma skin cancers (NMSCs) are the most common cancers worldwide and may be associated with significant morbidity and mortality, especially in immunosuppressed populations. …”
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“…The past decade has seen numerous advancements in approaches to melanoma detection, each with the common goal to stem the growing incidence of melanoma and its mortality rate. …”
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“…While primary genitourinary melanomas account for less than 1% of all melanoma cases, prostatic melanoma is extremely uncommon. …”
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“…This report presents a case of melanocytic matricoma with several unusual features that were initially feared to be malignant melanoma. Careful histologic and immunohistochemical analysis was required to rule out malignant melanoma and make the correct diagnosis. …”
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“…To our knowledge, bacteria in uveal melanoma have not been previously reported. OBSERVATIONS: We describe a patient with a large choroidal melanoma, measuring 18 × 16 mm in basal dimension and 15 mm in ultrasonographic thickness, managed by plaque brachytherapy. …”
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“…INTRODUCTION: There are vast differences in clinical presentations of melanoma across skin tones. Individuals with darker skin tones tend to have a higher prevalence of advanced-stage melanoma, which correlates with increased mortality. …”
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“…Mechanisms of anoikis resistance pose an attractive target for the therapeutic treatment of disseminating and circulating melanoma cells. This review explores the range of small molecule, peptide and antibody inhibitors targeting molecules involved in anoikis resistance in melanoma, and may be repurposed to prevent metastatic melanoma prior to its initiation, potentially improving the prognosis for patients.…”
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“…Adoptive cell therapy with tumor-infiltrating lymphocytes (TIL) is gaining momentum and demonstrating durable responses in patients with advanced melanoma. Although increasingly considered as a treatment option for select patients with melanoma, TIL therapy is not yet approved by any regulatory agency. …”
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“…METHODS: The effect of activation and radiation of CD95 receptors on melanoma cell lines was examined in vivo and in vitro. …”
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“…Malignant melanoma is one of the most common tumours and has the highest mortality rate of all types of skin cancers worldwide. …”
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“…When it comes to skin tumors and cancers, melanoma ranks among the most prevalent and deadly. …”
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“…The mechanism of bone destruction by melanomas involving Hh/Gli signaling in such a tumor microenvironment is unknown. …”
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