“…Acral melanoma is a rare subtype of melanoma that arises on the non-hair bearing skin of the nail bed, palms of the hand and soles of the feet. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVE: To describe the management of patients with occult anterior uveal melanomas presenting with extrascleral extension. METHODS AND ANALYSIS: Retrospective case series including five patients with small pigmented nodular mass on the episclera. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Therefore, a series of CA analogues were synthesized to evaluate their anti-melanoma activities across various melanoma cell lines. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The metastatic risk of uveal melanoma (UM) is defined by a limited number of molecular lesions, somatic mutations (SF3B1 and BAP1), and copy number alterations (CNA): monosomy of chromosome 3 (M3), chr8q gain (8q), chr6p gain (6p), yet the sequence of events is not clear. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Histologic examination concluded to a melanoma, most probably metastatic given the animal's previous medical history. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The incidence of melanoma has been dramatically increasing over the last decades. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Melanoma, a highly aggressive skin tumor, exhibits notable features including heterogeneity, a high mutational load, and innate immune escape. …”
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Uveal melanoma (UM) is the most common primary intraocular tumor in adults, leading to metastasis in 40% of the cases and ultimately to death in 10 years, despite local and/or systemic treatment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso

“…Between 1990 and 1999, 4774 female and 5688 male melanomas were diagnosed in Massachusetts residents. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The purpose of this case-control study was to identify susceptible subgroups, primarily based on pigmentary characteristics, at higher risk of developing melanoma when exposed to the sun. The study group, which was interviewed from 1979 to 1982, consisted of 289 consecutive patients with melanoma and 527 randomly selected controls without cancer. …”
Enlace del recurso
Enlace del recurso

“…The aim of this study was to investigate the correlation between radiotherapy or clinicohistopathological parameters and the expression of melan-A and tyrosinase in uveal melanoma. METHODS: Thirty-six enucleated cases of uveal melanoma were studied. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…QUESTIONS: What is the role of single-agent interleukin-2 (il-2) in the treatment of adults with metastatic melanoma? If there is a role for single-agent il-2, what patient population can appropriately be considered for treatment? …”
Enlace del recurso
Enlace del recurso

“…Primary malignant melanoma of the oesophagus is a rare neoplasm comprising less than 0.2% of all primary oesophageal neoplasms. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Using CM-1 antibody directed against the human p53 protein, high levels of mutant p53 protein expression were found in 12 out of 18 malignant choroidal melanomas. In contrast, we failed to observe elevated p53 expression, indicating the absence of p53 mutation in seven choroidal naevi, a potentially premalignant condition that can progress to form malignant melanoma. …”
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…In North America melanoma incidence increased with decreasing latitude, supporting the role of UV light in the induction of melanoma. …”
Enlace del recurso
Enlace del recurso

“…When injected i.v. into mice, the F10 subline of B16 melanoma cells produced significantly more lung tumours over a 3-week period than cells of the F101.r-6 subline. …”
Enlace del recurso
Enlace del recurso