-
1661
-
1662por Gaukroger, J., Wilson, L., Stewart, M., Farid, Y., Habeshaw, T., Harding, N., Mackie, R.“…Methotrexate (MTX) shows consistent cytotoxicity for melanoma cells in vitro but it is ineffective in clinical use at equivalent concentrations in vivo. …”
Publicado 1983
Enlace del recurso
Enlace del recurso
Texto -
1663“…Cell mediated immunocompetence was measured serially in 35 patients with malignant melanoma in order to determine the effect of extent of disease and prognosis as well as the influence of BCG immunotherapy on immune reactivity. …”
Enlace del recurso
Enlace del recurso
Texto -
1664“…The survival of clonogenic cells in the B16 melanoma has been studied simultaneously by 3 methods: an in vitro assay in soft agar, a lung-colony assay, and the end-point dilution technique. …”
Enlace del recurso
Enlace del recurso
Texto -
1665“…The role of genetic factors involved in the determination of risk of cutaneous malignant melanoma (CMM) in humans remains unclear owing to genetic heterogeneity and reliance on simplistic models of inheritance. …”
Enlace del recurso
Enlace del recurso
Texto -
1666por Easty, D. J., Maung, K., Lascu, I., Véron, M., Fallowfield, M. E., Hart, I. R., Bennett, D. C.“…Here we have studied NM23 expression during melanoma progression using Northern blotting and immunocytochemistry. …”
Publicado 1996
Enlace del recurso
Enlace del recurso
Texto -
1667Publicado 1990“…Melanoma growth-stimulatory activity (MGSA), a peptide reported to be mitogenic for Hs294T human melanoma cells, has extensive sequence similarity to the neutrophil-activating peptide NAP-1/IL-8, suggesting functional similarities. …”
Enlace del recurso
Enlace del recurso
Texto -
1668“…METHODS: HDACi-treated B16 melanoma cells were used in a murine vaccine model, lymphocyte subset depletion, ELISpot and Cytotoxicity assays were employed to evaluate immunity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1669por Pectasides, D., Yianniotis, H., Alevizakos, N., Bafaloukos, D., Barbounis, V., Varthalitis, J., Dimitriadis, M., Athanassiou, A.“…Twenty-seven patients with disseminated malignant melanoma were treated monthly with cisplatin (CDDP) 120 mg m-2 on day 1, vindesine (VDS) 3 mg m-2 on day 2 and dacarbazine (DTIC) 250 mg m-2 on days 2-6. …”
Publicado 1989
Enlace del recurso
Enlace del recurso
Texto -
1670por Stoeter, David, de Liguori Carino, Nicola, Marshall, Ernest, Poston, Graeme J, Wu, Andrew“…BACKGROUND: The prognosis for metastatic melanoma remains poor even with traditional decarbazine or interferon therapy. 5-year survival is markedly higher amongst patients undergoing metastatectomy. …”
Publicado 2008
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1671por Rasku, Mary Ann, Clem, Amy L, Telang, Sucheta, Taft, Beverly, Gettings, Kelly, Gragg, Hana, Cramer, Daniel, Lear, Sheron C, McMasters, Kelly M, Miller, Donald M, Chesney, Jason“…Sixteen patients received at least one cycle of DAB/IL2 and five of these patients experienced regressions of melanoma metastases as measured by CT and/or PET imaging. …”
Publicado 2008
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1672“…Temozolomide (TMZ), a DNA alkylating agent used in the treatment of melanoma, is believed to mediate its effect by addition of a methyl group to the O(6) position of guanine in DNA. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1673“…Malignant melanomas were supposed to harbour the human herpesvirus-type 8 (HHV-8) genome, as melanoma cells were reported to express interleukin-6 and a homologue of interleukin-6 was found in the HHV-8 genome. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1674por Feskanich, D, Hunter, D J, Willett, W C, Spiegelman, D, Stampfer, M J, Colditz, G A“…Melanoma has been increasing in white populations. …”
Publicado 1999
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1675por Landi, M T, Baccarelli, A, Calista, D, Pesatori, A, Fears, T, Tucker, M A, Landi, G“…A case–control study of non-familial melanoma including 183 incident cases and 179 controls was conducted in North-Eastern Italy to identify important risk factors and determine how combination of these affects risk in a Mediterranean population. …”
Publicado 2001
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1676“…As the chromosomal region 10q22-qter commonly is affected by losses in melanomas, we addressed this gene as tumour suppressor candidate in melanomas. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1677
-
1678
-
1679“…The past 30 years have only seen slight improvement in melanoma therapy. Despite a wide variety of therapeutic options, current survival for patients with metastatic disease is only 6–8 months. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1680“…In the work reported here, pO(2) was measured continuously over periods of at least 60 min in A-07 human melanoma xenografts by using the OxyLite fibre-optic oxygen-sensing device. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto