“…Cyst-like cavities in uveal melanoma occur rarely and can simulate a benign intraocular cystic lesion resulting in delayed diagnosis and inappropriate management. …”
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“…Malignant melanoma of the sphenoid sinus is a very rare disease, and only 6 cases have previously been reported. …”
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“…The incidence of melanoma is increasing steadily both in Poland and worldwide. …”
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“…These results indicated that VEGF can be an effective antiangiogenic strategy for melanoma.…”
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“…Melanomas demonstrate chromosomal instability (CIN). …”
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“…The clinical identification of amelanotic malignant melanoma (AMM) and hypomelanotic malignant melanoma (HMM) becomes difficult due to the lack of pigmentation and to the diverse clinical presentations. …”
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“…METHODS: In the present study we genotyped, 25 SNPs that tag 273 variants on chromosome 9p21 in 837 melanoma cases and 1154 controls from Spain. Ten SNPs were selected based on previous associations, reported in GWAS, with either melanocytic nevi or melanoma risk or both. …”
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“…Elevated level of OPN has been shown in melanoma patient and predicted as a prognostic marker. …”
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“…Introduction. Uveal melanoma (UM) is an intraocular tumor that leads to metastatic disease in approximately 50% of afflicted patients. …”
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“…BACKGROUND: Important risk factors for cutaneous melanoma (CM) are recognized, but standardized scores for individual assessment must still be developed. …”
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“…Epidermotropic metastatic melanoma is a rare form of cutaneous metastatic melanoma which can mimic primary melanoma on histopathology. …”
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“…In January 2010, the American Joint Committee on Cancer (AJCC) updated its staging criteria for uveal melanoma. Here, we discuss the staging classifications and evaluate an interesting case to demonstrate. …”
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“…A primary melanoma in an ovarian cystic teratoma originates most frequently at the dermoepidermal junction, similar to a cutaneous melanoma. …”
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“…Abstract Hypothesis: Melanoma is one of the most aggressive forms of skin cancer characterized by malignant proliferation of melanocytes. …”
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“…Ipilimumab, an anti-cytotoxic T lymphocyte antigen-4 (CTLA-4) antibody, is a new generation immunotherapeutic agent that has shown activity in terms of disease free and overall survival in metastatic melanoma patients. Its use was approved by the US Food and Drug Administration in March 2011 to treat patients with late stage melanoma that has spread or that cannot be removed by surgery. …”
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“…Here, we present a patient of psoriatic arthritis on long term methotrexate developing malignant melanoma.…”
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“…We report that simvastatin is able to induce apoptosis in melanoma cells but not in normal cells and also able to contrast the growth of tumor in an experimental melanoma murine model. …”
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“…Over 80% of the human melanoma cell lines expressed TGF-β, IL-8, IL-6, VEGF, PDGF-AA and OPN. …”
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“…Health care providers and their patients jointly participate in melanoma prevention, surveillance, diagnosis, and treatment. …”
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