“…Authors present a first ever reported case of an incidental liver metastasis found on intra-operative wedge hepatic biopsy during Whipple’s procedure for pancreatic cancer. …”
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“…Emerging evidence underscores its clinical relevance in tumor progression and its role in metastasis, one of the hallmarks of cancer. The multistep process of metastasis entails the acquisition of advantageous functions required for the formation of secondary tumors. …”
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“…Tumour metastasis is a multistep process. Melanoma is a highly aggressive cancer and metastasis accounts for the majority of patient deaths. microRNAs (miRNAs) are non-coding RNAs that affect the expression of their target genes. …”
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“…CONCLUSION: This illustrates a rare presentation of an advanced esophageal neoplasm. Subcutaneous metastasis from internal malignancies is unusual, corresponding to less than 10% of cases. …”
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“…An occipital scalp lesion was detected and biopsy confirmed cutaneous metastasis. Primary malignant bone tumors are rare but should be ruled out in young patients with persistent low back pain. …”
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“…The metastasis cascade is complex and comprises several stages including local invasion into surrounding tissue, intravasation and survival of tumour cells in the circulation, and extravasation and colonisation of a distant site. …”
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“…Mechanistically, we showed that the SIRT3 axis of UPR(mt) is necessary for invasion and metastasis. In breast cancer patients, a 7-gene UPR(mt) signature demonstrated that UPR(mt-HIGH) patients have significantly worse clinical outcomes, including metastasis. …”
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“…Metastasis is still poorly understood and thus further research must be conducted to provide insight into the driving factors. …”
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“…High cancer mortality is attributed to metastasis to a large extent. However, cancer metastasis remains devoid of dynamic monitoring and early prevention in terms of current advances in diagnostic means and therapeutic modalities. …”
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“…Only seven cases of brain metastasis from UC have been reported in the literature thus far. …”
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“…While microfluidic systems model aspects of metastasis, they are limited to artificially created tissues of limited complexity. …”
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“…Understanding the epidemiology of extremity skeletal metastasis and the factors deciding the treatment decision-making are essential in developing a diagnostic and treatment strategy. …”
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“…INTRODUCTION: Secondary pancreatic metastasis from other solid organ malignancy is rare and accounts for less than 2% of all pancreatic tumors. …”
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“…Cutaneous metastases of genitourinary malignancies are an extremely rare phenomenon. Few cases of skin metastasis from urothelial carcinoma of the bladder have been reported. …”
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“…Bone metastasis (BM) in cancer remains a critical issue because of its associated clinical and biological complications. …”
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“…In this review, we summarize recent progress in methods for engineering exosomes including isolation techniques and exogenous cargo encapsulation, with a focus on applications of engineered exosomes to target cancer metastasis.…”
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“…Endotracheal metastasis, a critical complication of primary lung cancer, is an extremely rare lesion. …”
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