“…The most common sites of metastasis in advanced hepatocellular carcinoma are the lung (44%), portal vein (35%), and portal lymph nodes (27%). …”
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“…Biopsy confirmed nail-bed HCC metastasis, and the finger was amputated. The patient died few weeks later. …”
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“…The distribution patterns of cancer metastasis depend on a sequence of steps involving adhesion molecules and on mechanical and geometrical effects related to blood circulation, but how much each of these two aspects contributes to the metastatic spread of a specific tumor is still unknown. …”
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“…Distant metastasis-free (DMFS) and MCC-specific (MSS) survival were estimated. …”
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“…Renal cell carcinoma (RCC) accounts for around 3% of all cases of skin metastasis. In these patients, solitary metastasis from RCC shows a favorable prognosis. …”
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“…Cutaneous melanoma (CM) is the most aggressive form of skin cancer, exhibits an increasing incidence worldwide and has a high potential to develop metastasis. The current study aimed to identify a set of parameters that may aid in predicting the probability and timing of the onset of CM metastasis. …”
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“…However, most of the established models lack the phenotype of invasion and metastasis in patient, or have unstable phenotype. To establish HCC models with stable metastasis phenotype requires profound understanding in cancer metastasis biology and scientific methodology. …”
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“…However, the impact of hepatic steatosis on liver metastasis is enigmatic. We find that while control mice were relatively resistant to hepatic metastasis, those which were lipodystrophic or obese, with NAFLD, had a dramatic increase in breast cancer and melanoma liver metastases. …”
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“…Metastasis formation accounts for the majority of tumor-associated deaths and consists of different steps, each of them being characterized by a distinctive adaptive phenotype of the cancer cells. …”
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“…PURPOSE: To report an unusual case of lung metastasis presenting as an eyelid lesion. OBSERVATIONS: An 82-year-old man presented with a right upper lid lesion of 2 weeks’ duration proven to be adenocarcinoma of the lung. …”
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“…The gingival lesion occurred 7 months after surgery; the metastasis was confirmed by a biopsy.…”
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“…Metastasis-directed therapy (MDT)—local therapy that is intended to eradicate specific metastatic lesions—has hitherto been used with varying degrees of clinical efficacy and acceptance as a meaningful therapy for metastatic disease. …”
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“…However, recent evidence suggests that during metastasis to the brain, cancer cells establish communication with the host. …”
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“…Metastasis refers to the progressive dissemination of primary tumour cells and their colonization of other tissues and is associated with most cancer‐related mortalities. …”
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