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90041“…There was no evidence of distant metastasis. She was commenced on levothyroxine post operatively. …”
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90042por Pishdad, Reza, Boutin, Regine, Hajjar, Richard, Jaloudi, Mohammed, Galan, Mark, Cespedes, Lissette Maria, Raghuwanshi, Maya P“…The patient was placed on thyroid hormone replacement therapy and was treated with external beam radiation to his bone metastasis. He was scheduled for later further thyroid ablation. …”
Publicado 2020
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90043“…Multivariate analysis revealed that mortality was associated with increasing age (OR 1.3 (95% CI 1.04–1.6) for each decade) and metastasis subgroup (lung vs. GU: OR 7.2 (95% CI 3.7–14)). …”
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90044por Aljomaiah, Abeer Abdulhadi, Moria, Yosra, Aldaej, Nora, Alswailem, Meshael, Alzahrani, Ali Saeed“…Lymph node metastases were present in 34 pts (92%) and distant metastases in 13 pts (35%). The sites of metastasis are lungs in 12 pts (32.4%) and lungs and bone in 1 pt. …”
Publicado 2020
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90045por Naranjo, Maria Belen, Rosenthal, David S, Kumar, Salini Chellappan, Shariff, Amal“…Case: 64 y/o African American female PMHX of lung non-small cell lung cancer diagnosed in 2017 Clinical stage IV with gluteal metastasis, and dementia. Pt was referred by Oncology. …”
Publicado 2020
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90046por Wells, Michael, Asmaro, Karam P, Sabedot, Thais S, Mosella, Maritza S, Malta, PharmD, Tathiane M, Nelson, Kevin, Snyder, James, deCarvalho, Ana, Mukherjee, Abir, Chitale, Dan, Robin, Adam, Rosenblum, Mark L, Mikkelsen, Tom, Poisson, Laila, Lee, Ian, Walbert, Tobias, Bhan, Arti, Kalkanis, Steven, Rock, Jack, Noushmehr, Houtan, Castro, Ana Valeria“…Methods and Findings: We conducted analyses of the methylomes of paired serum circulating cell-free DNA (cfDNA) and tumor tissue from patients harboring PT (EPIC array) to identify serum-derived pituitary tumor-specific methylation-based signatures (sPTMet n=37) in a cohort comprised by 13 patients with pituitary macroadenomas (9 males; median age: 62; 9 Nonfunctioning/4functioning, 6 invasive/7noninvasive), 4 controls (non-tumor) and patients with other CNS tumors or conditions (114 gliomas, 6 meningiomas, 1 brain metastasis, 1 colloid cyst, 6 radiation necrosis). Unsupervised and supervised analysis indicated that the serum methylome from patients harboring PT was distinct from controls and other CNS diseases. …”
Publicado 2020
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90047“…An MRI sella showed a completely normal pituitary and pineal gland with no evidence of brain metastasis. She thus met clinical and biochemical criteria for acromegaly but a pituitary source could not be identified. …”
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90048por Clines, Katrina L, Moon, Henry H, O’Day, Patrick J, Farber, Charles R, Auchus, Richard Joseph, Clines, Gregory A“…This concept is especially important in men with prostate cancer bone metastasis undergoing testicular-targeted therapies whereby adrenal DHEA may continue to fuel cancer growth, and in bone maturation during adrenarche before the pubertal rise in gonadal androgens.…”
Publicado 2020
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90049por Hillers-Ziemer, Lauren, McMahon, Rachel, Hieptas, Margaret, Paderta, Gretchen, McCready, Jessica, LeBeau, Jennelle, Arendt, Lisa“…Obese breast cancer patients often develop more aggressive tumors than lean patients and have increased risk for metastasis, tumor recurrence and mortality. Here, we sought to address how obesity alters the biology of breast cancer to promote aggressive tumors. …”
Publicado 2020
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90050“…There are three main types of anaplastic SCSC arising from TCV PTC based on histological characteristics: Type 1 is defined by the presence of both TCV and SCSC within the initial resection; type 2 refers to when the SCSC arises as a recurrence or metastasis in patients with a known history of TCV PTC; type 3 occurs when SCSC presents as a primary laryngeal SCC in patients with or without a known history of TCV. …”
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90051“…Subsequently, he underwent thyrogen stimulated I-131 ablation of residual thyroid carcinoma with pretherapy scan showing increased uptake in thyroid bed and a satellite lesion suspicious for LN metastasis. Post-ablative scan showed no other new lesions. …”
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90052“…Tumor was present at inked margin but no extrathyroidal extension was noted. There was a <1mm metastasis noted in 1 peri-isthmus lymph node. One month post operatively thyroglobulin was 123.5 ng/mL. …”
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90053“…Race, gender, and even lymph node metastasis were not significantly correlated with patient prognosis. …”
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90054por Yarema, Roman, Оhorchak, Мyron, Hyrya, Petro, Kovalchuk, Yuriy, Safiyan, Victor, Karelin, Ivan, Ferneza, Severyn, Fetsych, Markiyan, Matusyak, Myron, Oliynyk, Yuriy, Fetsych, Тaras“…BACKGROUND: Peritoneal metastasis (PM), arising from gastric cancer (GC), is the most common pattern of synchronous and metachronous dissemination and is generally associated with poor prognosis. …”
Publicado 2020
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90055por Zhang, Xi Yun, Rajagopalan, Deepa, Chung, Tae-Hoon, Hooi, Lissa, Toh, Tan Boon, Tian, Johann Shane, Rashid, Masturah Bte Mohd Abdul, Sahib, Noor Rashidha Bte Meera, Gu, Mengjie, Lim, Jhin Jieh, Wang, Wilson, Chng, Wee Joo, Jha, Sudhakar, Chow, Edward Kai-Hua“…G9a, a histone methyltransferase, has been found to promote disease progression, proliferation and metastasis via diverse mechanisms in several cancers. …”
Publicado 2020
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90056por Li, Xiaoying, Cui, Ming, Gu, Xiaobin, Fang, Dong, Li, Hongzhen, Qin, Shangbin, Yang, Kunlin, Zhu, Tianzhao, Li, Xuesong, Zhou, Liqun, Gao, Xian-Shu, Wang, Dian“…Ureter tumor, multifocality, T stage, G grade, lymph node metastasis (LNM), lymph node dissection (LND), and lymph vascular invasion (LVI) were all significantly associated with increased local recurrence by univariable analyses (P < 0.05). …”
Publicado 2020
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90057por Cao, Ming-xin, Zhang, Wei-long, Yu, Xiang-hua, Wu, Jia-shun, Qiao, Xin-wei, Huang, Mei-chang, Wang, Ke, Wu, Jing-biao, Tang, Ya-Jie, Jiang, Jian, Liang, Xin-hua, Tang, Ya-ling“…The low expression of miR-550a-3-5p correlated with higher tumor size and nodal metastasis of HPV-positive OSCC patients. Then, we found that miR-550a-3-5p suppressed the migration, invasion and EMT of HPV-positive OSCC cells dependent on decreasing M2 macrophages polarization. …”
Publicado 2020
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90058por Ascierto, Paolo Antonio, Del Vecchio, Michele, Mackiewicz, Andrzej, Robert, Caroline, Chiarion-Sileni, Vanna, Arance, Ana, Lebbé, Céleste, Svane, Inge Marie, McNeil, Catriona, Rutkowski, Piotr, Loquai, Carmen, Mortier, Laurent, Hamid, Omid, Bastholt, Lars, Dreno, Brigitte, Schadendorf, Dirk, Garbe, Claus, Nyakas, Marta, Grob, Jean-Jacques, Thomas, Luc, Liszkay, Gabriella, Smylie, Michael, Hoeller, Christoph, Ferraresi, Virginia, Grange, Florent, Gutzmer, Ralf, Pikiel, Joanna, Hosein, Fareeda, Simsek, Burcin, Maio, Michele“…In a subgroup analysis, median OS of patients with asymptomatic brain metastasis was 7.0 months (95% CI 4.0 to 12.8) in the 10 mg/kg group and 5.7 months (95% CI 4.2 to 7.0) in the 3 mg/kg group. …”
Publicado 2020
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90059por Chen, Shihan, Li, Kun, Jiang, Jiayun, Wang, Xiaofei, Chai, Yuelong, Zhang, Chang, Deng, Qingsong, Shuai, Ling, Feng, Kai, Ma, Kuansheng, Zhang, Leida“…Moreover, OATP1B3 expression was markedly correlated with tumor size, recurrence, tumor differentiation, and tumor node metastasis (TNM) stage (P < 0.05 for each). However, age, sex, tumor capsule status, HBsAg, cirrhosis, tumor number, vascular invasion, and serum alpha fetoprotein were not associated with OATP1B3 expression. …”
Publicado 2020
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90060por Gitto, Sarah B., Beardsley, Jordan M., Nakkina, Sai Preethi, Oyer, Jeremiah L., Cline, Kathryn A., Litherland, Sally A., Copik, Alicja J., Khaled, Amr S., Fanaian, Na’im, Arnoletti, J. Pablo, Altomare, Deborah A.“…RESULTS: Compound Akt1(Myr)/KRas(G12D) mice, compared to single KRas(G12D) or Akt1(Myr) mice, exhibited increased tissue damage after repeat inductions of inflammation, and had accelerated tumor development and metastasis. M2 macrophages and newly identified eosinophils co-localized with fibrotic regions rather than infiltrating into tumors, consistent with immune cell privilege. …”
Publicado 2020
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