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90141por Burgos, Nydia, Castellano, Janet Marie Colon, Nieves, Yadiel Rivera, Ramos, Nicolle Canales, Santini, Alberto Javier Grana, Cordero, Nicole Hernández, Feliciano-Emmanuelli, Melba, Gonzalez-Rodriguez, Loida Alejandra, Alvarado-Santiago, Milliette, Ramirez-Vick, Margarita“…However, most guidelines are in favor of surgical excision for tumors > 2 cm to decrease their associated risk for liver metastasis and improve long-term survival. In this young patient with a 3.2 cm tumor, a surgical approach was favored to improve prognosis. …”
Publicado 2021
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90142“…This FH mutation is associated with increased risk of metastasis in patients with PGL/PCC by a similar mechanism of carcinogenesis via the hypoxia pathway. …”
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90143por Balinski, Alexander M, Khatter, Neil J, Gold, Jeffrey M, Pothugunta, Krishna S, Garlapaty, Vamshi K, Rankin, Steven M, Thorburn, Christopher A, Abu-khaled, Jamal“…Case Presentation: A 45-year-old female presented with confusion, constipation, fatigue, and abdominal pain two weeks after total abdominal hysterectomy with bilateral salpingo-oophorectomy and suboptimal debulking of a newly discovered left ovarian mucinous adenocarcinoma with metastasis to the bladder, parametrium, vagina, right ovary, and rectosigmoid. …”
Publicado 2021
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90144“…Hypercalcemia seen in patients of VHL is either due to bone metastasis/PTHrP/IL-6 secretion from RCC or due to PTHrP/PTH/calcitonin secretion from pheochromocytoma and rarely due to associated parathyroid adenoma. …”
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90145por Findlay, Ryan, Gray, Daryl, Shepherd, Jessica, Joseph, Mariamma, Hussain, Nadeem, Laidley, David, Van Uum, Stan“…They are often aggressive, with 78.7% of reported cases having distant metastasis at diagnosis (1). They are associated with significant morbidity and mortality. …”
Publicado 2021
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90146por Al-Naqeeb, Ghadah, Neupane, Rabin, Baral, Neelam, Gao, Faye, Steves, Mark, Wexler, Jason Adam“…The pathology showed a well-differentiated neuroendocrine tumor of the pancreas, positive for synaptophysin, chromogranin and CD56 and Ki-67 with proliferation index <2% and no evidence of metastasis to the liver. The patient’s hypoglycemia resolved following surgery and rose to > 200 mg/dL requiring us to begin insulin therapy during the hospital stay before ultimately discharging the patient on metformin for type 2 diabetes. …”
Publicado 2021
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90147“…Four months later, the positron emission tomography (PET) scan was consistent with liver metastasis. Pembrolizumab, a programmed death receptor-1 (PD-1) inhibitor was initiated as next line treatment. …”
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90148“…This was confirmed on Abdominal MRI, which also showed multiple large hepatic metastasis. Tumor biopsy with pathology confirmed well differentiated neuroendocrine tumor of gastric or pancreatic origin. …”
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90149por Bjartell, Anders, Lumen, Nicolaas, Maroto, Pablo, Paiss, Thomas, Gomez-Veiga, Francisco, Birtle, Alison, Kramer, Gero, Kalinka, Ewa, Spaëth, Dominique, Feyerabend, Susan, Matveev, Vsevolod, Lefresne, Florence, Lukac, Martin, Wapenaar, Robert, Costa, Luis, Chowdhury, Simon“…However, the rate of visceral metastasis was higher in the AAP-PD cohort than in the AAP cohort (17.7% vs. 9.6%, respectively). …”
Publicado 2021
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90150por Zhou, Xingtong, Zheng, Zhibo, Li, Yan, Zhao, Weiwei, Lin, Yan, Zhang, Jieshi, Sun, Qiang“…Compared with IDC patients, MBC patients had less lymph node metastasis, an earlier stage, a higher rate of hormone receptor positivity and a lower expression rate of HER2. …”
Publicado 2021
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90151por Papp, L., Spielvogel, C. P., Grubmüller, B., Grahovac, M., Krajnc, D., Ecsedi, B., Sareshgi, R. A.M., Mohamad, D., Hamboeck, M., Rausch, I., Mitterhauser, M., Wadsak, W., Haug, A. R., Kenner, L., Mazal, P., Susani, M., Hartenbach, S., Baltzer, P., Helbich, T. H., Kramer, G., Shariat, S.F., Beyer, T., Hartenbach, M., Hacker, M.“…PURPOSE: Risk classification of primary prostate cancer in clinical routine is mainly based on prostate-specific antigen (PSA) levels, Gleason scores from biopsy samples, and tumor-nodes-metastasis (TNM) staging. This study aimed to investigate the diagnostic performance of positron emission tomography/magnetic resonance imaging (PET/MRI) in vivo models for predicting low-vs-high lesion risk (LH) as well as biochemical recurrence (BCR) and overall patient risk (OPR) with machine learning. …”
Publicado 2020
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90152“…The current study was conducted to investigate the effect of cytokine C–C motif chemokine ligand 21 (CCL21) on GC progression through the metastasis-associated lung adenocarcinoma transcript 1/serine arginine-rich splicing factor 1/mammalian target of rapamycin (MALAT1/SRSF1/mTOR) axis. …”
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90153“…A 71-year-old male with a history of malignancy of unknown primary with metastasis to the sacrum and vertebral column presented with lower limb weakness status post-palliative radiation to the spine. …”
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90154por Hammad, Ahmed, Zheng, Zhao-Hong, Namani, Akhileshwar, Elshaer, Mohamed, Wang, Xiu Jun, Tang, Xiuwen“…It was obvious that these pathways are closely associated with cancer development and metastasis. From the PPI network analyses, nine hub genes associated with CRC were identified. …”
Publicado 2021
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90155por Tang, Sun, Ou, Jing, Liu, Jun, Wu, Yu-ping, Wu, Chang-qiang, Chen, Tian-wu, Zhang, Xiao-ming, Li, Rui, Tang, Meng-jie, Yang, Li-qin, Tan, Bang-guo, Lu, Fu-lin, Hu, Jiani“…It is reported that radiomics can help predict preoperative stages of oesophageal SCC, lymph node metastasis before operation, and 3-year overall survival of oesophageal SCC patients following chemoradiotherapy by extracting high-throughput quantitative features from CT images. …”
Publicado 2021
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90156por Sharma, Vinod, Sharma, Atul, Raina, Vinod, Dabkara, Deepak, Mohanti, Bidhu Kalyan, Shukla, N. K., Pathy, Sushmita, Thulkar, Sanjay, Deo, S. V. S., Kumar, Sunil, Sahoo, Ranjit Kumar“…The three common sites of metastasis were the liver, peritoneum, and lung. In the first line, most patients received oxaliplatin-based chemotherapy (70%). …”
Publicado 2021
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90157“…BACKGROUND: The tumour microenvironment (TME) not only plays a role during tumour progression and metastasis but also profoundly influences treatment efficacy. …”
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90158por Zhang, Xiaobin, He, Yi, Gu, Haiyong, Liu, Zhichao, Li, Bin, Yang, Yang, Hao, Jie, Hua, Rong“…MicroRNAs (miRNAs) play a key role in the occurrence and metastasis and are closely related to the prognosis of EC. …”
Publicado 2021
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90159“…Cancer metabolism and specifically lipid metabolism plays an important role in pancreatic cancer progression and metastasis. Lipid droplets can not only store and transfer lipids, but also act as molecular messengers, and signaling factors. …”
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90160por Persson, Emma, Gregersson, Pernilla, Gustafsson, Anna, Fitzpatrick, Paul, Rhost, Sara, Ståhlberg, Anders, Landberg, Göran“…The secretomic profile that associated with cancer relapse and high grade breast cancer showed induced secretion of the proteins IL-6, CCL2 and PAI-1, all linked to cancer stem cell activation, metastasis and priming of the pre-metastatic niche. …”
Publicado 2021
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