“…HSP70 immunoreactivity in the cytoplasm of breast carcinoma cells was correlated with stage, lymph node metastasis, pathological T factor, histological grade, Ki-67 LI, and negatively correlated with ER and progesterone receptor (PR). …”
Enlace del recurso
Enlace del recurso

“…Regarding the staging Chest CT showed a metastasis suggestive nodulation; Cranial CT, bone scan and total spine MRI showed evidence of several infiltrative nodular formations with heterogeneous enhancement affecting the skullcap, sacrum, iliac bones and multiple vertebral bodies. …”
Enlace del recurso
Enlace del recurso

“…CLINICAL CASE: We report a case of a 34 year old female with metastatic neuroendocrine high grade tumor (WHO grade 3, non small cell, diagnosed 3 years prior to presentation) with metastasis to the bone (status post debulking and radiation) and brain (status post radiation therapy). …”
Enlace del recurso
Enlace del recurso

“…FDG PET-CT showed mild heterogeneous uptake of the adrenal mass with SUVmax of 5.1 and hepatic SUVmean of 2.5, without convincing metabolic evidence of metastasis. Mild uptake was noted in the mediastinal, hilar and left axillary lymph nodes, which were not suspiciously hypermetabolic and favored to be reactive, perhaps related to recent COVID-19 vaccination administered to the left upper extremity. …”
Enlace del recurso
Enlace del recurso

“…Chest x ray and NM full body PET CT did not show any evidence of granulomatous disease except for recurrence and metastasis of melanoma in right thigh, calf, and ankle. …”
Enlace del recurso
Enlace del recurso

“…CT chest abdomen pelvis, and octreotide scan had no evidence of metastasis. Due to vague abdominal discomfort, persistently high glucagon levels and pruritis without rash she was started on somatostatin analog therapy. …”
Enlace del recurso
Enlace del recurso

“…This revealed no evidence of cirrhosis or hepatic metastasis. Therefore, severe cholestasis was attributed to Stauffer syndrome, a paraneoplastic cholestatic jaundice from the underlying adrenal mass. …”
Enlace del recurso
Enlace del recurso

“…Progression-free survival (PFS), overall survival (OS), distant metastasis-free survival (DMFS) and locoregional relapse-free survival (LRFS) were compared between groups using propensity score matching (PSM). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recurrence-free survival (RFS), metastasis-free survival (MFS), cancer-specific survival (CSS), and overall survival (OS) were analyzed by the Kaplan-Meier method and log-rank test. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We constructed a prognostic nomogram incorporating pathological type, tumor-node-metastasis stage, and PDHA1 expression, and the C-index, calibration curve, and ROC curve revealed that the nomogram’s predictive performance was good. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Currently, the rate of recurrence or metastasis (ROM) remains high in rectal cancer (RC) patients treated with the standard regimen. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: (1) There were no significant differences in the 3-year overall survival (OS) rate, 3-year progression-free survival (PFS) rate, 5-year OS rate, and 5-year PFS rate among the three subgroups (p > 0.05). (2) The chemotherapy response rates of IA-NAC+RS group (37.5%) and IV-NAC+RS group (25.4%) were comparable (p > 0.05). (3) The intraoperative blood loss in the IA-NAC+RS group (average 92.13±84.09 mL) was significantly lower than that in the IV-NAC+RS group (average 127.2±82.36 mL) (p < 0.05). (4) The operation time of the IA-NAC+RS group (average 231.43±63.10 min) and the IV-NAC+RS group (average 219.82±49.11 min) were comparable (p > 0.05). (5) There were no significant differences between the IA-NAC+RS group and IV-NAC+RS group in pathological lymph node metastasis, parametrial invasion, and involvement of lymphovascular space (p > 0.05). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The effects of HCC cell-derived exosomes and the circ_002136 they carried on cell growth, metastasis and apoptosis were determined by CCK-8 assay, transwell assay, flow cytometry analysis and TUNEL staining, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…EOGC presented more advanced and undifferentiated tumors with G3/4 stages in 77% versus 62%, T3/4 stages in 51% versus 48%, nodal positive tumors in 57% versus 53% and metastasis in 35% versus 30% (p < 0.001) and received less curative treatment (42% versus 52%; p < 0.001). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The MLRH group mainly exhibited local single metastasis (7/11), whereas the ORH group mainly exhibited distant multiple metastases (14/16). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Based on the experimental data, in RCC, circNTNG1/miR-19b-3p/HOXA5 axis can regulate the epigenetic silencing of Slug, thus interfering EMT and metastasis of RCC. Together, our findings provide potential biomarkers and novel therapeutic targets for future study in RCC. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Factors affecting local progression-free survival (LPFS) were LN-SUVmax (P = 0.005), LN-TLG (P = 0.003) and NTR (P = 0.020), while clinical stage (P = 0.023), LN-SUVmax (P = 0.007), LN-TLG (P = 0.006), and NTR (P = 0.032) were factors affecting distant metastasis-free survival (DMFS). Multivariate analysis showed that NTR was an independent influencing factor of OS (HR 3.00, 95% CI 1.06–8.4, P = 0.038), LPFS (HR 3.08, 95% CI 1.27–7.50, P = 0.013), and DMFS (HR 1.84, 95% CI 0.99–3.42, P = 0.054). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Shared SNP alterations, with stable allele fraction from germline to metastasis were detected, mainly affecting DNA repair genes and promoting genome instability. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…PCSK9 inhibition or silencing is presently used in clinics worldwide to reduce LDL-cholesterol, resulting in lower incidence of cardiovascular disease and possibly cancer/metastasis. The mechanism by which the PCSK9-LDLR complex is sorted to degradation compartments is not fully understood. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Secondary endpoints were survival outcomes (local control, overall survival, distant metastasis free survival) and dosimetric advantages of adaptive process on targets volumes and OAR. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso