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90881por Wang, Hao, Zhou, Yongkang, Gan, Wutian, Chen, Hua, Huang, Ying, Duan, Yanhua, Feng, Aihui, Shao, Yan, Gu, Hengle, Kong, Qing, Xu, Zhiyong“…When neck lymph node metastasis was excluded from PTV(LN) volume, physical and EQD(2) total lung V(20) showed a high linear correlation with corrected volume ratio((LN to total lung).) …”
Publicado 2021
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90882por Rata, Mihaela, Khan, Khurum, Collins, David J, Koh, Dow-Mu, Tunariu, Nina, Bali, Maria Antonietta, d’Arcy, James, Winfield, Jessica M, Picchia, Simona, Valeri, Nicola, Chau, Ian, Cunningham, David, Fassan, Matteo, Leach, Martin O, Orton, Matthew R“…METHODS: This prospective imaging study enrolled 25 participants with colorectal liver metastases to receive Regorafenib treatment. A target metastasis > 2 cm in each patient was imaged before and at 15 days after treatment on a 1.5T MR scanner using slice-matched IVIM-DWI and DCE-MRI protocols. …”
Publicado 2021
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90883por Zhi, Jie, Jia, Xiao-Jing, Yan, Jing, Wang, Hui-Cong, Feng, Bo, Xing, Han-Ying, Jia, Yi-Tao“…BACKGROUND: BRAF(V600E) mutated colorectal cancer (CRC) is prone to peritoneal and distant lymph node metastasis and this correlates with a poor prognosis. …”
Publicado 2021
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90884“…Univariate analysis showed that there were significant differences in age, sex, history of diuretic use, distant metastasis, preoperative blood sodium, blood urea nitrogen (BUN), eGFR, TSH and urinary iodine between the two groups (all P < 0.05). …”
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90885por Szigeti, Florian, Schweighofer-Zwink, Gregor, Meissnitzer, Matthias, Hauser-Kronberger, Cornelia, Hitzl, Wolfgang, Kunit, Thomas, Forstner, Rosemarie, Pirich, Christian, Beheshti, Mohsen“…Distant bone and lymph node metastasis detected by [(68) Ga]Ga-PSMA-11 PET/CT were documented. [(68) Ga]Ga-PSMA-11 PET/CT findings were correlated with results of mpMRI and histopathology. …”
Publicado 2021
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90886por Kishan, Amar U., Steigler, Alison, Denham, James W., Zapatero, Almudena, Guerrero, Araceli, Joseph, David, Maldonado, Xavier, Wong, Jessica K., Stish, Bradley J., Dess, Robert T., Pilar, Avinash, Reddy, Chandana, Wedde, Trude B., Lilleby, Wolfgang A., Fiano, Ryan, Merrick, Gregory S., Stock, Richard G., Demanes, D. Jeffrey, Moran, Brian J., Tran, Phuoc T., Martin, Santiago, Martinez-Monge, Rafael, Krauss, Daniel J., Abu-Isa, Eyad I., Pisansky, Thomas M., Choo, C. Richard, Song, Daniel Y., Greco, Stephen, Deville, Curtiland, McNutt, Todd, DeWeese, Theodore L., Ross, Ashley E., Ciezki, Jay P., Tilki, Derya, Karnes, R. Jeffrey, Tosoian, Jeffrey J., Nickols, Nicholas G., Bhat, Prashant, Shabsovich, David, Juarez, Jesus E., Jiang, Tommy, Ma, T. Martin, Xiang, Michael, Philipson, Rebecca, Chang, Albert, Kupelian, Patrick A., Rettig, Matthew B., Feng, Felix Y., Berlin, Alejandro, Tward, Jonathan D., Davis, Brian J., Reiter, Robert E., Steinberg, Michael L., Elashoff, David, Boutros, Paul C., Horwitz, Eric M., Tendulkar, Rahul D., Spratt, Daniel E., Romero, Tahmineh“…OBJECTIVE: To determine the specific ADT duration threshold that provides a distant metastasis-free survival (DMFS) benefit in patients with high-risk prostate cancer receiving external beam radiotherapy (EBRT) or EBRT with a brachytherapy boost (EBRT+BT). …”
Publicado 2022
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90887por Arnoletti, Juan Pablo, Reza, Joseph, Rosales, Armando, Monreal, Alberto, Fanaian, Na’im, Whisner, Suzanne, Srivastava, Milan, Rivera-Otero, Julia, Yu, Gongxin, Phanstiel IV, Otto, Altomare, Deborah A., Tran, Quang, Litherland, Sally A.“…The portal venous circulation provides a conduit for pancreatic ductal adenocarcinoma (PDAC) tumor cells to the liver parenchyma sinusoids, a frequent site of metastasis. Turbulent flow in the portal circulation promotes retention of PDAC shed circulating tumor cells (CTC) and myeloid-derived immunosuppressor cells (MDSC). …”
Publicado 2022
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90888por Deleu, Anne-Leen, Laenen, Annouschka, Decaluwé, Herbert, Weynand, Birgit, Dooms, Christophe, De Wever, Walter, Jentjens, Sander, Goffin, Karolien, Vansteenkiste, Johan, Van Laere, Koen, De Leyn, Paul, Nackaerts, Kristiaan, Deroose, Christophe M.“…ROC analysis of paired SSTR/[(18)F]FDG SUV(max) values for the detection of metastasis of TC in 83 lymph node stations revealed an AUC of 0.91 for SSTR PET/CT and of 0.74 for [(18)F]FDG PET/CT (difference 0.17; 95% confidence interval − 0.03 to 0.38; p = 0.10). …”
Publicado 2022
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90889por Li, Xiaoya, Michels, Birgitta Elisabeth, Tosun, Oyku Ece, Jung, Janine, Kappes, Jolane, Ibing, Susanne, Nataraj, Nishanth Belugali, Sahay, Shashwat, Schneider, Martin, Wörner, Angelika, Becki, Corinna, Ishaque, Naveed, Feuerbach, Lars, Heßling, Bernd, Helm, Dominic, Will, Rainer, Yarden, Yosef, Müller-Decker, Karin, Wiemann, Stefan, Körner, Cindy“…Phenotypic effects of miR-183 overexpression in triple-negative breast cancer (TNBC) cell lines were investigated in vitro and in vivo by quantifying migration, proliferation, tumor growth and metastasis. Direct targeting of E2F1 by miR-183-5p|+2 was validated with a 3’UTR luciferase assay and linked to the phenotypes of isomiR overexpression. …”
Publicado 2022
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90890por Zaafouri, Haithem, Jouini, Raja, Khedhiri, Nizar, Khanchel, Fatma, Cherif, Mona, Mesbahi, Meryam, Daghmouri, Aziz, Mahmoudi, Wiem, Akremi, Soumaya, Sabbah, Meriam, Benzarti, Yazid, Hadded, Dhafer, Gargouri, Dalila, Bader, Mourad Ben, Maamer, Anis Ben“…The most common type of recurrence was peritoneal carcinomatosis in the SRCC group (62.5%) and hepatic metastasis in the non-SRCC group (60%; p = 0.096). The overall 5-year survival in the SRCC group was lower than in the non-SRCC group, with no statistically significant difference (47.1 vs 51.5%; p = 0.715). …”
Publicado 2022
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90891por Xu, Aqiao, Chu, Xiufeng, Zhang, Shengjian, Zheng, Jing, Shi, Dabao, Lv, Shasha, Li, Feng, Weng, Xiaobo“…Independent clinical predictors were identified through univariate logistic analysis (age, tumor location, ki-67 index, histological grade, and lymph node metastasis). Then, the radiomics signature with the best diagnostic performance (Rad score) was further combined with significant clinical risk factors to develop a clinicoradiomic model (nomogram) using multivariate logistic regression. …”
Publicado 2022
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90892por Zhu, Ping, Jin, Zhengxin, Kang, Guiyu, Jia, Yanfei, Liu, Duanrui, Zhang, Qian, Guo, Feiyang, Jia, Ying, Jiao, Yang, Li, Jingtan, Sun, Haiji, Ma, Xiaoli“…Our previous study reported that α5-nAChR mediates lung adenocarcinoma (LUAD) epithelial-mesenchymal transition (EMT) and metastasis via STAT3/Jab1. However, the link between α5-nAChR and PD-L1 is unclear in LUAD. …”
Publicado 2022
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90893por Zwager, L. W., Moons, L. M. G., Farina Sarasqueta, A., Laclé, M. M., Albers, S. C., Hompes, R., Peeters, K. C. M. J., Bekkering, F. C., Boonstra, J. J., ter Borg, F., Bos, P. R., Bulte, G. J., Gielisse, E. A. R., Hazen, W. L., ten Hove, W. R., Houben, M. H. M. G., Mundt, M. W., Nagengast, W. B., Perk, L. E., Quispel, R., Rietdijk, S. T., Rando Munoz, F. J., de Ridder, R. J. J., Schwartz, M. P., Schreuder, R. M., Seerden, T. C. J., van der Sluis, H., van der Spek, B. W., Straathof, J. W. A., Terhaar Sive Droste, J. S., Vlug, M. S., van de Vrie, W., Weusten, B. L. A. M., de Wijkerslooth, T. D., Wolters, H. J., Fockens, P., Dekker, E., Bastiaansen, B. A. J.“…BACKGROUND: T1 colorectal cancer (CRC) without histological high-risk factors for lymph node metastasis (LNM) can potentially be cured by endoscopic resection, which is associated with significantly lower morbidity, mortality and costs compared to radical surgery. …”
Publicado 2022
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90894por Petkov, Stefan, Kilpeläinen, Athina, Bayurova, Ekaterina, Latanova, Anastasia, Mezale, Dzeina, Fridrihsone, Ilse, Starodubova, Elizaveta, Jansons, Juris, Dudorova, Alesja, Gordeychuk, Ilya, Wahren, Britta, Isaguliants, Maria“…Immunizations with other PR variants were not protective; all mice formed tumors and multiple metastasis in the lungs, liver, and spleen. CD8+ cells of PR_Ai3mut DNA-immunized mice exhibited strong IFN-γ/IL-2 responses against PR peptides, while the splenocytes of mice in other groups were nonresponsive. …”
Publicado 2022
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90895por Meacci, Elisa, Nachira, Dania, Congedo, Maria Teresa, Ibrahim, Mohsen, Pariscenti, Gianluca, Petrella, Francesco, Casiraghi, Monica, De Stefani, Alessandro, del Regno, Laura, Peris, Ketty, Triumbari, Elizabeth Katherine Anna, Schinzari, Giovanni, Rossi, Ernesto, Petracca-Ciavarella, Leonardo, Vita, Maria Letizia, Chiappetta, Marco, Siciliani, Alessandra, Peritore, Valentina, Manitto, Mattia, Morelli, Lucia, Zanfrini, Edoardo, Tabacco, Diomira, Calabrese, Giuseppe, Bardoni, Claudia, Evangelista, Jessica, Spaggiari, Lorenzo, Margaritora, Stefano“…Twenty-six (14.2%) patients already had a synchronous lung metastasis at the time of primary melanoma diagnosis. …”
Publicado 2023
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90896por Rockall, Andrea G., Li, Xingfeng, Johnson, Nicholas, Lavdas, Ioannis, Santhakumaran, Shalini, Prevost, A. Toby, Punwani, Shonit, Goh, Vicky, Barwick, Tara D., Bharwani, Nishat, Sandhu, Amandeep, Sidhu, Harbir, Plumb, Andrew, Burn, James, Fagan, Aisling, Wengert, Georg J., Koh, Dow-Mu, Reczko, Krystyna, Dou, Qi, Warwick, Jane, Liu, Xinxue, Messiou, Christina, Tunariu, Nina, Boavida, Peter, Soneji, Neil, Johnston, Edward W., Kelly-Morland, Christian, De Paepe, Katja N., Sokhi, Heminder, Wallitt, Kathryn, Lakhani, Amish, Russell, James, Salib, Miriam, Vinnicombe, Sarah, Haq, Adam, Aboagye, Eric O., Taylor, Stuart, Glocker, Ben“…The study aim was to develop a machine learning (ML) algorithm to improve radiologists' sensitivity and specificity for metastasis detection and reduce reading times. MATERIALS AND METHODS: A retrospective analysis of 438 prospectively collected WB-MRI scans from multicenter Streamline studies (February 2013–September 2016) was undertaken. …”
Publicado 2023
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90897por Ghoussaini, Maya, Fletcher, Olivia, Michailidou, Kyriaki, Turnbull, Clare, Schmidt, Marjanka K, Dicks, Ed, Dennis, Joe, Wang, Qin, Humphreys, Manjeet K, Luccarini, Craig, Baynes, Caroline, Conroy, Don, Maranian, Melanie, Ahmed, Shahana, Driver, Kristy, Johnson, Nichola, Orr, Nicholas, Silva, Isabel dos Santos, Waisfisz, Quinten, Meijers-Heijboer, Hanne, Uitterlinden, Andre G., Rivadeneira, Fernando, Hall, Per, Czene, Kamila, Irwanto, Astrid, Liu, Jianjun, Nevanlinna, Heli, Aittomäki, Kristiina, Blomqvist, Carl, Meindl, Alfons, Schmutzler, Rita K, Müller-Myhsok, Bertram, Lichtner, Peter, Chang-Claude, Jenny, Hein, Rebecca, Nickels, Stefan, Flesch-Janys, Dieter, Tsimiklis, Helen, Makalic, Enes, Schmidt, Daniel, Bui, Minh, Hopper, John L, Apicella, Carmel, Park, Daniel J, Southey, Melissa, Hunter, David J, Chanock, Stephen J, Broeks, Annegien, Verhoef, Senno, Hogervorst, Frans BL, Fasching, Peter A., Lux, Michael P., Beckmann, Matthias W., Ekici, Arif B., Sawyer, Elinor, Tomlinson, Ian, Kerin, Michael, Marme, Frederik, Schneeweiss, Andreas, Sohn, Christof, Burwinkel, Barbara, Guénel, Pascal, Truong, Thérèse, Cordina-Duverger, Emilie, Menegaux, Florence, Bojesen, Stig E, Nordestgaard, Børge G, Nielsen, Sune F, Flyger, Henrik, Milne, Roger L., Alonso, M. Rosario, González-Neira, Anna, Benítez, Javier, Anton-Culver, Hoda, Ziogas, Argyrios, Bernstein, Leslie, Dur, Christina Clarke, Brenner, Hermann, Müller, Heiko, Arndt, Volker, Stegmaier, Christa, Justenhoven, Christina, Brauch, Hiltrud, Brüning, Thomas, Wang-Gohrke, Shan, Eilber, Ursula, Dörk, Thilo, Schürmann, Peter, Bremer, Michael, Hillemanns, Peter, Bogdanova, Natalia V., Antonenkova, Natalia N., Rogov, Yuri I., Karstens, Johann H., Bermisheva, Marina, Prokofieva, Darya, Khusnutdinova, Elza, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M, Lambrechts, Diether, Yesilyurt, Betul T., Floris, Giuseppe, Leunen, Karin, Manoukian, Siranoush, Bonanni, Bernardo, Fortuzzi, Stefano, Peterlongo, Paolo, Couch, Fergus J, Wang, Xianshu, Stevens, Kristen, Lee, Adam, Giles, Graham G., Baglietto, Laura, Severi, Gianluca, McLean, Catriona, Alnæs, Grethe Grenaker, Kristensen, Vessela, Børrensen-Dale, Anne-Lise, John, Esther M., Miron, Alexander, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Kauppila, Saila, Andrulis, Irene L., Glendon, Gord, Mulligan, Anna Marie, Devilee, Peter, van Asperen, Christie J., Tollenaar, Rob A.E.M., Seynaeve, Caroline, Figueroa, Jonine D, Garcia-Closas, Montserrat, Brinton, Louise, Lissowska, Jolanta, Hooning, Maartje J., Hollestelle, Antoinette, Oldenburg, Rogier A., van den Ouweland, Ans M.W., Cox, Angela, Reed, Malcolm WR, Shah, Mitul, Jakubowska, Ania, Lubinski, Jan, Jaworska, Katarzyna, Durda, Katarzyna, Jones, Michael, Schoemaker, Minouk, Ashworth, Alan, Swerdlow, Anthony, Beesley, Jonathan, Chen, Xiaoqing, Muir, Kenneth R, Lophatananon, Artitaya, Rattanamongkongul, Suthee, Chaiwerawattana, Arkom, Kang, Daehee, Yoo, Keun-Young, Noh, Dong-Young, Shen, Chen-Yang, Yu, Jyh-Cherng, Wu, Pei-Ei, Hsiung, Chia-Ni, Perkins, Annie, Swann, Ruth, Velentzis, Louiza, Eccles, Diana M, Tapper, Will J, Gerty, Susan M, Graham, Nikki J, Ponder, Bruce A. J., Chenevix-Trench, Georgia, Pharoah, Paul D.P., Lathrop, Mark, Dunning, Alison M., Rahman, Nazneen, Peto, Julian, Easton, Douglas F“…Two of the loci lie in regions that contain strong plausible candidate genes: PTHLH (12p11) plays a crucial role in mammary gland development and the establishment of bone metastasis in breast cancer, while NRIP1 (21q21) encodes an ER co-factor and has a role in the regulation of breast cancer cell growth.…”
Publicado 2012
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90898por Xiang, Michael, Ma, Ting Martin, Savjani, Ricky, Pollom, Erqi L., Karnes, R. Jeffrey, Grogan, Tristan, Wong, Jessica K., Motterle, Giovanni, Tosoian, Jeffrey J., Trock, Bruce J., Klein, Eric A., Stish, Bradley J., Dess, Robert T., Spratt, Daniel E., Pilar, Avinash, Reddy, Chandana, Levin-Epstein, Rebecca, Wedde, Trude B., Lilleby, Wolfgang A., Fiano, Ryan, Merrick, Gregory S., Stock, Richard G., Demanes, D. Jeffrey, Moran, Brian J., Huland, Hartwig, Tran, Phuoc T., Martin, Santiago, Martinez-Monge, Rafael, Krauss, Daniel J., Abu-Isa, Eyad I., Alam, Ridwan, Schwen, Zeyad, Pisansky, Thomas M., Choo, C. Richard, Song, Daniel Y., Greco, Stephen, Deville, Curtiland, McNutt, Todd, DeWeese, Theodore L., Ross, Ashley E., Ciezki, Jay P., Boutros, Paul C., Nickols, Nicholas G., Bhat, Prashant, Shabsovich, David, Juarez, Jesus E., Chong, Natalie, Kupelian, Patrick A., Rettig, Matthew B., Zaorsky, Nicholas G., Berlin, Alejandro, Tward, Jonathan D., Davis, Brian J., Reiter, Robert E., Steinberg, Michael L., Elashoff, David, Horwitz, Eric M., Tendulkar, Rahul D., Tilki, Derya, Czernin, Johannes, Gafita, Andrei, Romero, Tahmineh, Calais, Jeremie, Kishan, Amar U.“…Biochemical recurrence (BCR), distant metastasis (DM), prostate cancer–specific mortality (PCSM), and overall survival (OS) were analyzed using Fine-Gray and Cox regressions. …”
Publicado 2021
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90899por Lin, Dongmei, Wang, Hui, Liu, Lu, Zhao, Liang, Chen, Jing, Tian, Hongyan, Gao, Lei, Wu, Beibei, Zhang, Jing, Guo, Xia, Hao, Yi“…The prognosis of patients with early EC is good; however, high-risk EC patients have a poor prognosis because they have a higher risk of tumor recurrence, lymph node metastasis, and distant tumor spread. At present, there are no structured ultrasound reporting standards for endometrial lesions. …”
Publicado 2022
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90900por Zhu, Yixiang, Liu, Chengcheng, Xu, Ziyi, Zou, Zihua, Xie, Tongji, Xing, Puyuan, Wang, Le, Li, Junling“…However, intracranial activity varies in different drugs. Thus, brain metastasis (BM) should be considered when choosing the treatment regimens. …”
Publicado 2023
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