“…Dapsone is not an ideal drug, however. It generates methemoglobinemia that occasionally is symptomatic. This generation is reduced by concomitant use of the antacid drug cimetidine. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, it has been found that nitrocompounds are capable of inhibiting pathogens, parasites, methane and ammonia production; however, overdose of nitrocompounds could cause methemoglobinemia or interfere with energy production in mitochondria by inhibiting succinate dehydrogenase.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Comprehensive tests were performed, but Dapsone-induced methemoglobinemia remained the exclusive explanation for the observed scenario, although arterial MetHb analysis showed a peak value of only 6%. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…They are usually available at higher dosages and have serious potential adverse reactions, such as seizures, anaphylaxis, and acquired methemoglobinemia. To date, the scope of application of herbal plants and their extracts, which have medicinal properties, has been elaborated in the field of dentistry. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…At the time of admission, she presented with methemoglobinemia and septic shock, which was due to immunosuppression caused by the normal dose of Dapsone. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Methylene blue (MB) has unique energy-enhancing and antioxidant properties and is FDA-approved drug to treat methemoglobinemia and cyanide poisoning. This study evaluated the efficacy of MB to treat ischemic stroke in rats using longitudinal MRI and behavioral measures. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Rasburicase-induced hemolysis and methemoglobinemia is a rare but serious complication. Screening for G6PD should be considered for patients at higher risk for G6PD deficiency who may be also at high risk for TLS on the basis of clinical parameters. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…High-nitrate drinking water can cause methemoglobinemia, while nitrosamines are associated with various human cancers. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The endogenous conditions include not only benign (angioleiomyoma, hemangioma, melanocytic macule, and varicosities) and malignant (ovarian carcinoma) tumors but also reactive lesions (intravascular papillary endothelial hyperplasia and mucocele) and systemic disorders (argyria, cyanosis, methemoglobinemia, primary adrenal insufficiency, and thrombocytosis). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recessive congenital methemoglobinemia (RCM) is a rare neurological disorder caused by a deficiency in NADH-CYB5R. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Its pharmacological properties have also been applied toward the treatment of certain diseases such as methemoglobinemia, ifosfamide-induced encephalopathy, and thyroid conditions requiring surgery. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The greatest risk posed by nitrates is hemoglobin oxidation, which results in Methemoglobin in the human body, resulting in Methemoglobinemia. There are many ways to eliminate nitrates from underground water. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The pollution of groundwater with nitrate is a serious issue because nitrate can cause several diseases such as methemoglobinemia or cancer. Therefore, selective removal of nitrate by efficient binding to supramolecular hosts is highly desired. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Among the CYB5R genetic variants, CYB5R3 is well-characterized and deficiency in expression and activity is associated with type II methemoglobinemia, cancer, neurodegenerative disorders, diabetes, and cardiovascular disease. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In more severe reactions, significant leukocytosis with neutrophilia, thrombocytosis, metabolic derangements, methemoglobinemia, anemia, low albumin, and total protein may be present. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Laboratory findings are characterized by anemia, reticulocytosis, elevated bilirubin level, and sometimes urinary urobilinogen and methemoglobinemia. In most cases the symptomatology is self-limited and does not release sequelae, but hospitalization and transfusion are often required.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Using chemical criteria, no significant risk from ingestion or dermal contact was identified at the method detection limits at any site, except from nitrate exposure: infants and young children are at risk from methemoglobinemia at all sites. Results suggest that pathogen risk interventions are a priority, whereas nitrate risk needs further characterization to determine if formal treatment is needed. …”
Enlace del recurso
Enlace del recurso

“…Chemical hypoxemia through methemoglobinemia was induced by daily intraperitoneal injection of sodium nitrite (40 mg/kg) for 4 weeks in rats with fatty liver. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Depending on the severity, metabolic acidosis and methemoglobinemia may occur. In chronic cases, anemia, hypoalbuminemia and eosinophilia may be seen. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…They differ from “acquired haemoglobinopathies”, such as methemoglobinemia, in which hemoglobin is usually compromised due to the action of toxic substances. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso