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  1. 138641
    “…The third fragments with the grade II or III displacement should be treated with closed reduction whenever possible to achieve a displacement within the range of grade I to minimize the incidence of nonunion.…”
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    Effect of the degree of displacement of the third fragment on healing of femoral shaft fracture treated by intramedullary nailing
  2. 138642
    “…SWiM-C is a guided self-help programme using non-specialist guides to enhance scalability and population reach while minimizing cost. This study evaluated the effect of SWiM-C on bodyweight, eating behaviour, physical activity, and mental wellbeing in adults with overweight and obesity over 4 months during the COVID-19 pandemic in the UK. …”
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    Supporting Weight Management during COVID-19: A Randomized Controlled Trial of a Web-Based, ACT-Based, Guided Self-Help Intervention
  3. 138643
    “…We retrospectively analyzed the clinical, histopathological, and molecular data of 3,254 Chinese patients with preinvasive lesions (n = 252), minimally invasive adenocarcinomas (n = 479), and invasive LUAD (n = 2,523). …”
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    Distinct mutational features across preinvasive and invasive subtypes identified through comprehensive profiling of surgically resected lung adenocarcinoma
  4. 138644
    “…BACKGROUND: The role of social ties, other-regarding preferences, and cultural traits in boosting community resilience and minimizing citizens’ vulnerability to crises such as COVID-19 is increasingly being recognized. …”
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    The school education, ritual customs, and reciprocity associated with self-regulating hand hygiene practices during COVID-19 in Japan
  5. 138645
    “…BACKGROUND: Percutaneous pedicle screw (PPS) placement is a key step in several minimally invasive spinal surgery (MISS) procedures. …”
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    Intraoperative CT-guided navigation versus fluoroscopy for percutaneous pedicle screw placement in 192 patients: a comparative analysis
  6. 138646
    por Cebeci, Oğuz Özden
    Publicado 2022
    “…Most cases of IUI are not recognized until the patient presents with symptoms following pelvic surgery or radiotherapy. Recently, minimally invasive approaches have been used more frequently in the treatment of IUI. …”
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    Is endourological intervention a suitable treatment option in the management of iatrogenic thermal ureteral injury? A contemporary case series
  7. 138647
    “…Regarding clinical context, participants desired more clinics with accessible locations/hours; streamlined testing that minimized use of waiting rooms and wait times; and improved clinic ambience. …”
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    Community perspectives on ideal bacterial STI testing services for gay, bisexual, and other men who have sex with men in Toronto, Canada: a qualitative study
  8. 138648
    “…The value in Hounsfield units per sample head was averaged from three individual measurements to minimize fluctuations. For biomechanical and histomorphological evaluation, the samples were extracted in the load bearing zone perpendicular to the surface of the femoral head. …”
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    Atraumatic femoral head necrosis: a biomechanical, histological and radiological examination compared to primary hip osteoarthritis
  9. 138649
    “…Careful clinical report design can help ensure that benefits are realized and harms are minimized. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13073-022-01117-8.…”
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    Patient and provider perspectives on polygenic risk scores: implications for clinical reporting and utilization
  10. 138650
    “…However, few studies have analysed the composition of their ‘minimally-manipulated’ cellular products in parallel, information that is vital to understand the mechanisms by which these therapies may be efficacious. …”
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    The composition of cell-based therapies obtained from point-of-care devices/systems which mechanically dissociate lipoaspirate: a scoping review of the literature
  11. 138651
    por Espinoza, Josh L., Dupont, Chris L.
    Publicado 2022
    “…VEBA fully integrates both end-to-end and task-specific metagenomic analysis in a modular architecture that minimizes dependencies and maximizes productivity. …”
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    VEBA: a modular end-to-end suite for in silico recovery, clustering, and analysis of prokaryotic, microeukaryotic, and viral genomes from metagenomes
  12. 138652
    “…Future studies should examine the directionality and underlying causality of the observed associations, and possibly identify target interventions to minimize impairment associated with hoarding symptomatology. …”
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    Hoarding symptoms are associated with higher rates of disability than other medical and psychiatric disorders across multiple domains of functioning
  13. 138653
    “…METHODS: De novo systematic reviews will be conducted to synthesize the available evidence on (a) the benefits and harms of interventions to reduce potentially inappropriate prescriptions and OTC medications compared to no intervention, usual care, or non- or minimally active intervention among adults aged 65 years and older and (b) the acceptability of these interventions or attributes among patients. …”
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    Interventions to address potentially inappropriate prescriptions and over-the-counter medication use among adults 65 years and older in primary care settings: protocol for a systematic review
  14. 138654
    “…BACKGROUND: Intramedullary nail (IMN) is one of the key essential minimally invasive “weapons” in orthopaedic trauma, while the distal locking is still challenging for surgeons. …”
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    Comparison of freehand technique and a novel laser guiding navigation in distal locking of femoral intramedullary nails: a randomized controlled trial
  15. 138655
    “…It is crucial to achieve a maximum tumour dose for an optimal treatment response, while minimizing healthy liver dose to prevent toxicity. There is, however, no intraprocedural feedback on the dose distribution, as nuclear imaging can only be performed after treatment. …”
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    Intraprocedural MRI-based dosimetry during transarterial radioembolization of liver tumours with holmium-166 microspheres (EMERITUS-1): a phase I trial towards adaptive, image-controlled treatment delivery
  16. 138656
    por Olivier, Timothée, Prasad, Vinay
    Publicado 2022
    “…BACKGROUND: In the adjuvant setting of cancer treatment, de-escalation strategies have the goal of omitting or minimizing treatment in patients, without compromising outcomes. …”
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    Molecular testing to deliver personalized chemotherapy recommendations: risking over and undertreatment
  17. 138657
    “…BACKGROUND: Minimally invasive surgery is complex and associated with substantial learning curves. …”
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    Computer-aided anatomy recognition in intrathoracic and -abdominal surgery: a systematic review
  18. 138658
    “…Beyond using non-boosted ART to minimize pDDIs, other factors related to the practice of chemsex must be addressed, in order to offer a better approach. …”
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    Do ART and Chemsex Drugs Get Along? Potential Drug–Drug Interactions in a Cohort of People Living with HIV Who Engaged in Chemsex: A Retrospective Observational Study
  19. 138659
    “…Initiating SSRIs only in those individuals at highest risk for PSD may help reduce the burden of stroke recovery in this targeted population while minimizing adverse side effects.…”
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    In-hospital predictors of post-stroke depression for targeted initiation of Selective Serotonin Reuptake Inhibitors (SSRIs)
  20. 138660
    “…We propose an optimal treatment allocation strategy which is derived from minimizing the standard error of the log odds ratio estimate of the comparison of interest. …”
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    Using information from network meta-analyses to optimize the power and sample allocation of a subsequent trial with a new treatment
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