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138681A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosapor Neumayer, Gernot, Torkelson, Jessica L., Li, Shengdi, McCarthy, Kelly, Zhen, Hanson H., Vangipuram, Madhuri, Jackow, Joanna, Rami, Avina, Hansen, Corey, Guo, Zongyou, Gaddam, Sadhana, Pappalardo, Alberto, Li, Lingjie, Cramer, Amber, Roy, Kevin R., Nguyen, Thuylinh Michelle, Tanabe, Koji, McGrath, Patrick S., Bruckner, Anna, Bilousova, Ganna, Roop, Dennis, Bailey, Irene, Tang, Jean Y., Christiano, Angela, Steinmetz, Lars M., Wernig, Marius, Oro, Anthony E.“…Validated iPS cells are converted into epidermal, dermal and melanocyte progenitors with a novel 2D organoid differentiation protocol, followed by CD49f enrichment and expansion to minimize maturation heterogeneity. iSC product characterization by single cell transcriptomics was followed by mouse xenografting for disease correcting activity at 1 month and toxicology analysis at 1–6 months. …”
Publicado 2023
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138682por He, Weili, Wei, Weidong, Zhang, Qing, Lv, Rongzhao, Qu, Shaohua, Huang, Xin, Ma, Juan, Zhang, Ping, Zhai, Hening, Wang, Ningxia“…The age and length of hospital stay were significantly different in patients undergoing open surgery than minimally invasive rotary cutting surgery and mammoscopic-assisted glandular resection (P < 0.01). …”
Publicado 2023
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138683“…Through its fluctuating disease activity and unpredictable attacks, hereditary angioedema (HAE) imposes a substantial patient burden. To minimize HAE burden and improve quality of life, treatment should involve individualized management strategies that address on-demand therapy and short-term/long-term prophylaxis. …”
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138684por Quinn, Emma, Hsiao, Kai Hsun, Johnstone, Travers, Gomez, Maria, Parasuraman, Arun, Ingleton, Andrew, Hirst, Nicholas, Najjar, Zeina, Gupta, Leena“…BACKGROUND: Early detection and response to influenza and COVID-19 outbreaks in aged care facilities (ACFs) are critical to minimizing health impacts. The Sydney Local Health District (SLHD) Public Health Unit (PHU) has developed and implemented a novel web-based app with integrated functions for online line listings, detection algorithms, and automatic notifications to responders, to assist ACFs in outbreak response. …”
Publicado 2023
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138685por Migliorini, Filippo, Bell, Andreas, Vaishya, Raju, Eschweiler, Jörg, Hildebrand, Frank, Maffulli, Nicola“…At last follow-up, all patients were minimally symptomatic or asymptomatic, and no additional therapy or attentions were required by any patient. …”
Publicado 2023
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138686“…All stakeholders should hence work together to minimize individuals’ COVID-19-related resource losses to prevent depression in the general population, as COVID-19 might be lasting. …”
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138687“…The non-adherence was significantly associated with the ISI (OR 0.16; CI 0.03–0.73; p < 0.018) for invasive methods compared with minimally invasive ones). There was a significant positive correlation between harm reporting and both the CSBQ of the publishing journal and the HDI of the recruited research sample country (p = 0.001, p = 0.003, respectively). …”
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138688por He, Jieyi, Wang, Wanhui, Ning, Peishan, Schwebel, David C., Yang, Yang, Cheng, Peixia, Li, Jie, Zhao, Min, Li, Weiqiang, Zhang, Na, Liu, Han, Hu, Guoqing“…External support strategies will be implemented by local partners to minimize attrition. Data collection will be conducted at baseline and then every 3 months during a 12-month follow-up time period. …”
Publicado 2023
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138689por Shafieesabet, Azadeh, Jauert, Nadja, Hartmann, Oliver, Arlt, Birte, Joebges, Michael, Doehner, Wolfram“…The plasma bio-ADM level was analyzed in association with 6-month all-cause mortality as well as a composite outcome of all-cause mortality, unscheduled re-hospitalization, or transfer to a long-term care facility in a vegetative or minimally conscious state. Bio-ADM levels significantly increased in patients with ischemic stroke who died compared to surviving patients (40.4 pg/ml vs. 23.8 pg/ml, p < 0.001) or in those with composite outcomes compared to those with no events (36.9 pg/ml vs. 23.5 pg/ml, p < 0.001). …”
Publicado 2023
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138690“…Therefore, focusing extra attention on these high-risk individuals could reduce delayed first antenatal care visit and this further minimizes maternal and fetal health concerns by recognizing and acting early.…”
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138691por Bruno, Bethany, Mercer, Mary Beth, Hizlan, Sabahat, Peskin, Julian, Ford, Paul J., Farrell, Ruth M., Rose, Susannah L.“…Obstetric providers should explore telemedicine to improve access – and, during the ongoing pandemic, to minimize exposures – using patients’ experiences for guidance. …”
Publicado 2023
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138692“…BACKGROUND: Minimally invasive surgery has been used to treat anterior mediastinal tumors. …”
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138693por Scheuermann, S., Tan, A., Govender, P., Mckie, M., Pack, J., Martinez, G., Falter, F., George, S., A. Klein, A.“…BACKGROUND: Minimally invasive surgery is becoming more common and transfemoral transcatheter aortic valve replacement is offered to older patients with multiple comorbidities. …”
Publicado 2023
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138694“…We demonstrate a relationship between the tidal cycle and foraging that is likely to minimize predation risk while maximizing energetic efficiency. …”
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138695por Munk, Lizzie, van Essen, Tom, van der Hoeven, Casper, Nolte, Peter A., Becker, Matthijs L.“…BACKGROUND: Compliance with perioperative anticoagulation guidelines is essential to minimize bleeding and thromboembolic risks in patients undergoing surgery. …”
Publicado 2023
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138696“…The APP defines adequate on the global rating scale (GRS) as the minimally acceptable standard for an entry-level physiotherapist. …”
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138697por Huang, Kai, Wu, Xian, Li, Yixin, Lv, Chengzhi, Yan, Yangtian, Wu, Zhe, Zhang, Mi, Huang, Weihong, Jiang, Zixi, Hu, Kun, Li, Mingjia, Su, Juan, Zhu, Wu, Li, Fangfang, Chen, Mingliang, Chen, Jing, Li, Yongjian, Zeng, Mei, Zhu, Jianjian, Cao, Duling, Huang, Xing, Huang, Lei, Hu, Xing, Chen, Zeyu, Kang, Jian, Yuan, Lei, Huang, Chengji, Guo, Rui, Navarini, Alexander, Kuang, Yehong, Chen, Xiang, Zhao, Shuang“…By making the model minimize the MAE value, the model becomes closer to the target value. …”
Publicado 2023
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138698por Hirst, Yasemin, Stoffel, Sandro T, Brewer, Hannah R, Timotijevic, Lada, Raats, Monique M, Flanagan, James M“…CONCLUSIONS: This UK-based survey study shows that willingness to share commercial data for health research varies; however, researchers should focus on effectively communicating their data practices to minimize concerns about data misuse and improve public trust in data science. …”
Publicado 2023
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138699por Rayegani, Seyed Mansoor, Soltani, Vahid, Cheraghi, Mohsen, Omid Zohor, Mohammad Reza, Babaei-Ghazani, Arash, Raeissadat, Seyed Ahmad“…BACKGROUND: Lumbosacral canal stenosis is known as the most common cause of back surgery with several complications. Selecting a minimally invasive treatment with high efficacy in such patients is necessary. …”
Publicado 2023
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138700por Mothes, Anke R., Kather, Angela, Cepraga, Irina, Esber, Anke, Kwetkat, Anja, Runnebaum, Ingo B.“…Study design Because of current demographic developments, a hypothesis was proposed whereby older female patients aged > 65 years can be safely operated using minimally invasive, robotic-assisted surgery, despite having more preoperative comorbidities. …”
Publicado 2023
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