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  1. 138841
    “…Compensatory approaches to PM rehabilitation have been found to minimize the impact of PM impairment in adults with TBI; however, poor self-awareness after TBI poses a major barrier to the generalization of compensatory strategies in daily life. …”
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    The efficacy of prospective memory rehabilitation plus metacognitive skills training for adults with traumatic brain injury: study protocol for a randomized controlled trial
  2. 138842
    “…MRI-guided single dose ablative APBI has the potential to offer a minimally burdening, non-invasive treatment that could replace current breast-conserving therapy. …”
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    Redefining radiotherapy for early-stage breast cancer with single dose ablative treatment: a study protocol
  3. 138843
    “…Inverse propensity weighting was used to minimize bias from missing data. RESULTS: Pre-operative global and heart failure-specific health status were very poor: KCCQ median 34.6 (IQR 21.4-50.5); VAS median 43 (interquartile range (IQR) 25–65). …”
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    Association of global and disease-specific health status with outcomes following continuous-flow left ventricular assist device implantation
  4. 138844
    “…RESULTS: ELF2B overexpression significantly reduced cell proliferation and clonogenic capacity, minimally disrupted cell cycle kinetics, and induced apoptosis. …”
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    The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vitro and perturbs early lymphocytic development in vivo
  5. 138845
    “…Included were the optimal frequency of EMA prompts to maximize data collection without overburdening participants; the timing and scheduling of EMA prompts; technological lessons to support a longitudinal study, such as proper communication between the Android smartphone, the Web server, and the database server; and use of a phone that provided access to the system’s functionality for EMA data collection to avoid loss of data and minimize the impact of loss of network connectivity. …”
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    Ecological Momentary Assessment in Behavioral Research: Addressing Technological and Human Participant Challenges
  6. 138846
    “…BACKGROUND: Electromagnetic navigation bronchoscopy (ENB) is an image-guided, minimally invasive approach that uses a flexible catheter to access pulmonary lesions. …”
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    Electromagnetic navigation bronchoscopy to access lung lesions in 1,000 subjects: first results of the prospective, multicenter NAVIGATE study
  7. 138847
    “…However, when a single dose of plerixafor is administered at a conventional 240 μg/kg dose, approximately one-third of donors will fail to mobilize the minimally acceptable dose of CD34(+) cells needed for allogeneic transplantation. …”
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    Effect of high-dose plerixafor on CD34(+) cell mobilization in healthy stem cell donors: results of a randomized crossover trial
  8. 138848
    por Chaib, Imane, Karachaliou, Niki, Pilotto, Sara, Codony Servat, Jordi, Cai, Xueting, Li, Xuefei, Drozdowskyj, Ana, Servat, Carles Codony, Yang, Jie, Hu, Chunping, Cardona, Andres Felipe, Vivanco, Guillermo Lopez, Vergnenegre, Alain, Sanchez, Jose Miguel, Provencio, Mariano, Reguart, Noemi, Zhou, Caicun, Cao, Peng, Ma, Patrick C., Bivona, Trever G., Rosell, Rafael, Chaib, Imane, Karachaliou, Niki, Pilotto, Sara, Servat, Jordi Codony, Cai, Xueting, Li, Xuefei, Drozdowskyj, Ana, Servat, Carles Codony, Yang, Jie, Hu, Chunping, Cardona, Andres Felipe, Vivanco, Guillermo Lopez, Vergnenegre, Alain, Sanchez, Jose Miguel, Provencio, Mariano, de Marinis, Filippo, Passaro, Antonio, Carcereny, Enric, Reguart, Noemi, Campelo, Charo Garcia, Teixido, Cristina, Sperduti, Isabella, Rodriguez, Sonia, Lazzari, Chiara, Verlicchi, Alberto, de Aguirre, Itziar, Queralt, Cristina, Wei, Jia, Estrada, Roger, de la Bellacasa, Raimon Puig, Ramirez, Jose Luis, Jacobsen, Kirstine, Ditzel, Henrik J., Santarpia, Mariacarmela, Viteri, Santiago, Molina, Miguel Angel, Zhou, Caicun, Cao, Peng, Ma, Patrick C., Bivona, Trever G., Rosell, Rafael
    Publicado 2017
    “…Conclusions: Our study uncovers a coordinated signaling network centered on both STAT3 and Src-YAP signaling that limits targeted therapy response in lung cancer and identifies an unforeseen rational upfront polytherapy strategy to minimize residual disease and enhance clinical outcomes.…”
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    Co-activation of STAT3 and YES-Associated Protein 1 (YAP1) Pathway in EGFR-Mutant NSCLC
  9. 138849
    “…CONCLUSIONS: Together, our results indicate that SMI-mediated inhibition of the CD40-TRAF6 pathway skews human monocytes towards anti-inflammatory cells with reduced trans-endothelial migration capacity, and is able to reduce CNS-infiltrated monocyte-derived macrophages during neuro-inflammation, but minimally ameliorates EAE disease severity. We therefore conclude that SMI-mediated inhibition of the CD40-TRAF6 pathway may represent a beneficial treatment strategy to reduce monocyte recruitment and macrophage activation in the CNS and has the potential to be used as a co-treatment to combat MS. …”
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    Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation
  10. 138850
    “…Based on social security numbers (anonymously treated), we have excluded from our analyses all re-hospitalizations of the same patients (n = 1,878,109) over the entire 11-year period in order to minimize the overlap between prevalent and incident cancer cases. …”
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    Hospitalizations in Pediatric and Adult Patients for All Cancer Type in Italy: The EPIKIT Study under the E.U. COHEIRS Project on Environment and Health †(,)‡
  11. 138851
    “…Analysis of isolated murine muscles reveals that nanospan is mostly associated with the ZSR and triadic SR, and only minimally with the LSR. Furthermore, nanospan is absent from the SR of δ-SG-null (Sgcd(−/−)) skeletal muscle, a murine model for limb girdle muscular dystrophy 2F. …”
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    Nanospan, an alternatively spliced isoform of sarcospan, localizes to the sarcoplasmic reticulum in skeletal muscle and is absent in limb girdle muscular dystrophy 2F
  12. 138852
    “…BACKGROUND: Interventional radiology includes a range of minimally invasive image-guided diagnostic and therapeutic procedures that have become routine clinical practice. …”
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    Evaluation of the clinical benefit of an electromagnetic navigation system for CT-guided interventional radiology procedures in the thoraco-abdominal region compared with conventional CT guidance (CTNAV II): study protocol for a randomised controlled trial
  13. 138853
    “…The results will be available to current and future initiatives aiming to improve detection of MR need and making MR accessible to EWEC patients needing such support to minimize the effects of chronic disease on their livess. …”
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    Fostering needs assessment and access to medical rehabilitation for patients with chronic disease and endangered work ability: protocol of a multilevel evaluation on the effectiveness and efficacy of a CME intervention for general practitioners
  14. 138854
    “…BACKGROUND: Minimally invasive specific biomarkers of neurodegenerative diseases (NDs) would facilitate patient selection and disease progression monitoring. …”
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    Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases
  15. 138855
    “…The ability to measure Aβ oligomer levels in the blood would provide simple and minimally invasive tools for AD diagnostics. In the present study, the recently developed Multimer Detection System (MDS) for AD, a new enzyme-linked immunosorbent assay for measuring Aβ oligomers selectively, was used to detect Aβ oligomers in the plasma of patients with AD and healthy control individuals. …”
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    Oligomeric forms of amyloid-β protein in plasma as a potential blood-based biomarker for Alzheimer’s disease
  16. 138856
    “…The aim of the study is to determine if this minimally invasive approach improves quality of life, satisfaction and clinical morbimortality outcomes. …”
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    Quality of life, satisfaction and outcomes after ministernotomy versus full sternotomy isolated aortic valve replacement (QUALITY-AVR): study protocol for a randomised controlled trial
  17. 138857
    “…METHODS: This is a controlled, randomized, clinical trial using the minimization method, with blinding of those who will evaluate the outcomes and two parallel groups for the purpose of showing superiority. …”
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    Efficacy of high-intensity, low-volume interval training compared to continuous aerobic training on insulin resistance, skeletal muscle structure and function in adults with metabolic syndrome: study protocol for a randomized controlled clinical trial (Intraining-MET)
  18. 138858
    “…Augmentation of healthcare workers’ skills and involvement can mediate gender power differentials, minimize fear and shorten time to male partner disclosure among women living with HIV, regardless of their PMTCT cascade status. …”
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    HIV status disclosure to male partners among rural Nigerian women along the prevention of mother-to-child transmission of HIV cascade: a mixed methods study
  19. 138859
    “…Well-matched control patients minimized confounding effects. Small effects and lack of significant differences may be explained by a low baseline DNa(+) limiting the interventional change. …”
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    Effects of dialysate to serum sodium (Na(+)) alignment in chronic hemodialysis (HD) patients: retrospective cohort study from a quality improvement project
  20. 138860
    “…BACKGROUND: Self-management of diabetes minimizes the risk of macrovascular and microvascular complications, but understanding and/or adherence to self-management recommendations is often suboptimal. …”
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    DIABEO App Software and Telemedicine Versus Usual Follow-Up in the Treatment of Diabetic Patients: Protocol for the TELESAGE Randomized Controlled Trial
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