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“…We proposed two versions of the new mouse model, iMM1865 and min-iMM1865, with the same number of gene-associated reactions but different subsets of non-gene-associated reactions. …”
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“…INTRODUCTION: The aim of this article was to evaluate the safety and efficiency of flexible ureteroscopy (fURS) in the management of renal calculi larger than 20 mm. MATERIAL AND METHODS: A total of 92 cases with renal calculi were managed with fURS and divided into two groups depending on the size of the stones; <20 mm and >20 mm (Group 1 and Group 2, respectively). …”
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“…We have implemented our new approach, mmCSM-AB, as a web-server that can help guide the process of affinity maturation in antibody design. mmCSM-AB is freely available at http://biosig.unimelb.edu.au/mmcsm_ab/.…”
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“…We present a detailed investigation for realizing sub-mm long on-chip laser structures operating at λ = 1.533 µm on the silicon-on-insulator photonic platform by combining a multi-segment silicon waveguide structure and a recently demonstrated erbium-doped thin film deposition technology. …”
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“…Towards a distributed neural interface, consisting of multiple miniaturized implants, for interfacing with large-scale neuronal ensembles over large brain areas, this paper presents a mm-sized free-floating wirelessly-powered implantable opto-electro stimulation (FF-WIOS2) device equipped with 16-ch optical and 4-ch electrical stimulation for reconfigurable neuromodulation. …”
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“…A new design approach for a mmWave high gain planar antenna is presented. The proposed method can increase antenna directivity with a minimally enlarged radiation patch while the operation frequency is still matched at a higher target frequency. …”
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“…OBJECTIVE: To report the use of a 3 mm rigid nasal endoscope in primary endoscopic stapedotomy and clinical and audiological outcomes. …”
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“…The absorption spectra are simulated by exploiting a fully polarizable quantum mechanical (QM)/molecular mechanics (MM) model, based on the fluctuating charge (FQ) force field. …”
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“…MATERIALS AND METHODS: We retrospectively analyzed 404 patients who underwent extracorporeal shockwave lithotripsy for 5–20-mm renal stones between April 2011 and March 2019. …”
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“…We present a technique of doubling a commercially available 3 mm dermal allograft and making it into a 6 mm graft for superior capsule reconstruction.…”
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“…OBJECTIVE: To evaluate the stability, insertion torque, removal torque and pain associated with 3 mm long MSIs placed in humans by a novice clinician. …”
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“…We investigate several mechanisms of covalent modification of C481 in BTK by ibrutinib using combined quantum mechanics/molecular mechanics (QM/MM) molecular dynamics reaction simulations. The lowest energy pathway involves direct proton transfer from C481 to the acrylamide warhead in ibrutinib, followed by covalent bond formation to form an enol intermediate. …”
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“…Herein, a single-layer phase gradient metasurface lens is presented to achieve millimeter-wave focusing at a focal point of 13 mm regardless of the incident angle. The proposed metasurface lens is fabricated by constructing subwavelength-thick (< λ/10) phase elements composed of two metallic layers separated by a single dielectric substrate that exhibits low-Q resonance properties and a wide phase modulation range with satisfactory transmissivity. …”
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“…This paper presents a novel adaptive object movement and motion tracking (AdaMM) framework in a hierarchical edge computing system for achieving GPU memory footprint reduction of deep learning (DL)-based video surveillance services. …”
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“…While a number of computational methods to assess the effects of variants on protein–protein binding affinity have been proposed, they are in general limited to the analysis of single point mutations and have been shown to perform poorly on independent test sets. Here, we present mmCSM-PPI, a scalable and effective machine learning model for accurately assessing changes in protein–protein binding affinity caused by single and multiple missense mutations. …”
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“…We also found that precipitation reconstructions based on tree-ring data and the Palmer Drought Severity Index almost exclusively fall in the region of the 200- to 600-mm annual precipitation isolines, not other regions. …”
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“…Here we present a detailed exploration of the activation mechanism through a QM/MM approach focusing on both steps of the reaction, aiming to provide new insights into the deprotonation process and the role of the catalytic machinery in the methyl-transfer reaction. …”
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