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145921por Lee, Bo Bin, Kim, Dongho, Kim, Yujin, Han, Joungho, Shim, Young Mog, Kim, Duk-Hwan“…Activity of DNMTs was reduced by about 2.6-fold in A549 cells treated with 10 mM metformin for 72 h. miR-148/-152 family members (miR-148a, miR-148b, and miR-152) targeting the 3′UTR of DNMTs were associated with post-transcriptional regulation of DNMTs by metformin. …”
Publicado 2023
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145922por Garg, Megha, Johnson, Hans, Lee, Su-min, Rai, Bhavan Prasad, Somani, Bhaskar, Philip, Joe“…Stone size ranged from 4 to 30 mm in diameter. Mean stone density was used by two-third of the studies to predict the appropriate cut-off for SWL success, ranging from 750 to 1000 HU. …”
Publicado 2023
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145923“…The reconstructions had average surface errors between 1.59 and 3.59 mm with reconstructions using the contour error metric from the AP/ML directions being the most accurate. …”
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145924por Doran, James, Canty, David, Dempsey, Karen, Cass, Alan, Kangaharan, Nadarajah, Remenyi, Bo, Brunsdon, Georgie, McDonald, Malcolm, Heal, Clare, Wang, Zhiqiang, Royse, Colin, Royse, Alistair, Mein, Jacqueline, Gray, Nigel, Bennetts, Jayme, Baker, Robert A, Stewart, Maida, Sutcliffe, Steven, Reeves, Benjamin, Doran, Upasna, Rankine, Patricia, Fejo, Richard, Heenan, Elisabeth, Jalota, Ripudaman, Ilton, Marcus, Roberts-Thomson, Ross, King, Jason, Wyber, Rosemary, Doran, Jonathan, Webster, Andrew, Hanson, Joshua“…Preoperative chronic kidney disease (HR 6.5 (95% CI: 3.0 to 14.0) p≤0.001)), coronary artery disease (HR 3.3 (95% CI: 1.3 to 8.4) p=0.012) and pulmonary artery systolic pressure>50 mm Hg before surgery (HR 1.9 (95% CI: 1.2 to 3.1) p=0.007) were independently associated with death. …”
Publicado 2023
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145925por Zhang, Shangming, Chen, Qizuan, Xian, Liang, Chen, Yehuang, Wei, Liangfeng, Wang, Shousen“…ICP increased to 56.9 ± 2.3 mmHg, mean arterial pressure showed reactive decrease, and the blood flow of cerebral cortical arteries and veins on the non-SDH-affected side decreased to < 10%. …”
Publicado 2023
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145926“…The outer diameter measured less than 4 mm in MPD was regarded as the standard of precluding safe C2 pedicle screw insertion. …”
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145927por Vera Quesada, César Luis, Rao, Shreyas Balachandra, Torp, Reidun, Eide, Per Kristian“…The dura specimens were obtained average 16.1 ± 4.5 mm lateral to the superior sagittal sinus in the right frontal region (about 12 cm posterior to glabella). …”
Publicado 2023
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145928por Saito, Kenta, Matsuo, Yoichi, Denda, Yuki, Nonoyama, Keisuke, Murase, Hiromichi, Kato, Tomokatsu, Hayashi, Yuichi, Imafuji, Hiroyuki, Morimoto, Mamoru, Ogawa, Ryo, Takahashi, Hiroki, Takiguchi, Shuji“…A contrast-enhanced computed tomography scan showed a 12-mm hypervascular mass near the ampulla of Vater. …”
Publicado 2023
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145929“…Fourteen days after GnRHa administration, the transvaginal ultrasound revealed six follicles measuring 17-26 mm in the bilateral ovaries. The patient was given 10000 IU of human chorionic gonadotropin. …”
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145930por Kotani, Kohei, Enomoto, Masaru, Uchida-Kobayashi, Sawako, Tamori, Akihiro, Yukawa-Muto, Yoshimi, Odagiri, Naoshi, Motoyama, Hiroyuki, Kozuka, Ritsuzo, Kawamura, Etsushi, Hagihara, Atsushi, Fujii, Hideki, Kageyama, Ken, Yamamoto, Akira, Yoshida, Atsushi, Higashiyama, Shigeaki, Kawabe, Joji, Kawada, Norifumi“…However, the percentage with severe portal hypertension (defined as HVPG ≥ 12 mmHg) decreased from 92% pre-treatment to 58% after SVR24 (p = 0.046). …”
Publicado 2023
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145931por Maurer, H. Carlo, Curiel-Garcia, Alvaro, Holmstrom, Sam, Laise, Pasquale, Palermo, Carmine F., Sastra, Steven A., Andren, Anthony, Li, Zhang, LeLarge, Tessa, Sagalovskiy, Irina, Ross, Daniel R., Rosario, Vilma, Lu, Kate, Ferraiuolo, Ethan, Spinosa, Nicholas, Wong, Winston, Shaw, Kaitlin, Chabot, John A., Genkinger, Jeanine, Hibshoosh, Hanina, Manji, Gulam A., Iuga, Alina, Schmid, Roland M., Badgley, Michael A., Johnson, Kristen, Califano, Andrea, Lyssiotis, Costas, Olive, Kenneth P.“…We previously demonstrated that PDAC is hypovascularized and hypoperfused, and here show that PDAC from the genetically engineered KPC model exists in a state of extreme hypoxia, with a partial oxygen pressure of <1mmHg. Given the close homology of BMAL2 to HIF1β (ARNT) and its potential to heterodimerize with HIF1A and HIF2A, we investigated whether BMAL2 plays a role in the hypoxic response of PDAC. …”
Publicado 2023
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145932por Xue, Ruizhi, Hu, Caoyang, Zheng, Zhongyi, Wei, Liang, Yuan, Xiaobin, Lyu, Xiao, Shen, Pengliang, Li, Jun, Cao, Xiaoming“…RESULTS: Among all the groups, the intervention group had the minimal bleeding volume (28.93 ± 25.94 ml, p < 0.05), the least intraoperative blood pressure variation (59.11 ± 25.68 mmHg, p < 0.05), the shortest operation time (115.32 ± 30.69 min, p < 0.05), the lowest postoperative ICU admission rates (7.14%, p < 0.05), and shortest drainage time length (2.57 ± 0.50 days, p < 0.05). …”
Publicado 2023
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145933“…Cage subsidence was defined as ≥ 2 mm of cage migration into the inferior endplate, superior endplate, or both. …”
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145934“…Increasing the ionic strength from 0.1 to 100 mM enhanced the adsorption capacity of C18Q(SBA) from 9.27 ± 0.42 to 14.94 ± 0.17 mg/g because the hydrophobic interactions were increased while the electrostatic attraction of the N(+) was reduced. …”
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145935“…Primary outcomes were subjective levels of hunger and satiety measured by a 100 mm visual analogue scale in relation to a standard breakfast meal (453 kcal) and energy and macronutrient intake determined by a 3-day diet diary at 0, 3 and 6 months. …”
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145936“…The presence of severe COVID-19 symptoms was evaluated by the infectious disease specialist and included dyspnea, SpO2 < 94% on room air, PaO2/FiO2 < 300 mm Hg, a respiratory rate > 30 breaths/min, and lung infiltrates > 50%. …”
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145937por Yan, Xinyu, Zhang, Xiaoqi, Ren, Linghuan, Yang, Yi, Wang, Qingxuan, Gao, Yanzi, Jiang, Qingsong, Jian, Fan, Long, Hu, Lai, Wenli“…Excessive labial movement (0.7 mm) of incisors may be achieved. Incisor movement is influenced by predicted movement amount, premolar extraction, canine proclination, molar distalization, mini-implants and age.…”
Publicado 2023
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145938por Dave, Rajiv V., Elsberger, Beatrix, Taxiarchi, Vicky P., Gandhi, Ashu, Kirwan, Cliona C., Kim, Baek, Camacho, Elizabeth M., Coles, Charlotte E., Copson, Ellen, Courtney, Alona, Horgan, Kieran, Fairbrother, Patricia, Holcombe, Chris, Kirkham, Jamie J., Leff, Daniel R., McIntosh, Stuart A., O’Connell, Rachel, Pardo, Ricardo, Potter, Shelley, Rattay, Tim, Sharma, Nisha, Vidya, Raghavan, Cutress, Ramsey I.“…There were small reductions in median tumour size after 3 months’ treatment duration; median of 4 mm [IQR − 20, 4]. In a small subset of patients (n = 47), a drop in cellular proliferation (Ki67) occurred in 26 patients (55%), from high (Ki67 ≥ 10%) to low (< 10%), with at least one month’s duration of BrET. …”
Publicado 2023
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145939“…Two partially 1 cm apart threaded 4.0-mm cancellous screws were used to secure the graft. …”
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145940por Jungen, Samuel H., Noti, Luca, Christe, Lucine, Galvan, Jose A., Zlobec, Inti, Müller, Michael D., Imboden, Sara, Siegenthaler, Franziska, Carlson, Joseph W., Pellinen, Teijo, Heredia-Soto, Victoria, Ruz-Caracuel, Ignacio, Hardisson, David, Redondo, Andres, Mendiola, Marta, Rau, Tilman T.“…In the testing cohort, intra-tumoral densities of less than 50 intra-tumoral CD8(+) cells/mm(2) were the most suitable parameter to assume a POLEwt, irrespective of an MMRdef, NSMP or p53abn background. …”
Publicado 2023
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