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1441“…In this article, the quantum mechanical/molecular mechanical (QM/MM) molecular dynamics (MD) and free energy simulations are performed to study SDMA catalyzed by the Type II PRMT5 on the basis of experimental observation that the dimethylated product is generated through a distributive fashion. …”
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1442“…The temperature sensor chip has been designed and fabricated in a 0.13 μm CMOS process, with a total active die area of 0.0014 mm(2). The sensor only draws a 140 nA current from a 1.1 V supply, with the key transistors working in the deep subthreshold region. …”
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1443“…We sought to develop and validate a clinical nomogram model for predicting overall survival (OS) in non-small-cell lung cancer (NSCLC) patients with resected tumors that were 30 mm or smaller, using clinical data and molecular marker findings. …”
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1444por Ni, Debin, Yu, Guoqiang, Shi, Shengnan, Xu, Dong, Chu, Enyi, Yu, Chunpei, Zhen, Zilong, Zhang, Wenchao“…The electrical ignition experiments have exhibited outstanding ignition ability, since the electronic initiator can easily fire the insensitive ignition composition of boron-potassium nitrate (B-KNO(3)) tablet in a gap of 20.35 mm. It proves that this novel proposal of remoulding the traditional electronic ignition devices will distinctly improve the ignition ability and reliability of electronic initiator.…”
Publicado 2019
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1445“…We took rainfall as a fixed influencing factor and selected four typical soils of China to investigate the bacterial effects of biochar and chemical fertilizer at 25 mm rainfall, and to identify specific differential bacteria and their functions, and to explore the changes of the bacterial community structure of different soil types. …”
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1446por Shen, Tengming, Bosque, Ernesto, Davis, Daniel, Jiang, Jianyi, White, Marvis, Zhang, Kai, Higley, Hugh, Turqueti, Marcos, Huang, Yibing, Miao, Hanping, Trociewitz, Ulf, Hellstrom, Eric, Parrell, Jeffrey, Hunt, Andrew, Gourlay, Stephen, Prestemon, Soren, Larbalestier, David“…These round multifilamentary wires exhibited a record J(E) up to 950 A/mm(2) at 30 T at 4.2 K. These coils carried up to 8.6 kA while generating 3.5 T at 4.2 K at a J(E) of 1020 A/mm(2). …”
Publicado 2019
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1447por Aksomaitiene, Jurgita, Ramonaite, Sigita, Novoslavskij, Aleksandr, Malakauskas, Mindaugas, Kudirkiene, Egle“…This study describes a draft whole genome sequence of C jejuni MM26-781 isolated from a common pigeon (Columba livia) in Lithuania in 2011 and assigned to ST-6424 (CC179) sequence type. …”
Publicado 2019
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1448“…The high-add IOL LENTIS® MAX LS-313 MF80 (Oculentis, Germany) was implanted in the right eye and the 7.0 mm optic ASPIRA-aXA IOL (HumanOptics, Germany) in the left eye. …”
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1449por Pawar, Prashant, Vadivelu, Ramalingam, Bachani, Neeta, Jeyashree, Kathiresan, Sharma, Rajeev, Rathi, Chetan, Jadwani, Jaipal, Bera, Debabrata, Lokhandwala, Yash“…CONCLUSION: Conventional RF ablation using PV potential-based mapping and ablation with 8 mm tip catheters is safe for patients with PAF. …”
Publicado 2019
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1450por Casalvieri, Kimberly A., Matheson, Christopher J., Backos, Donald S., Reigan, Philip“…The molecular mechanics energies combined with the generalized Born and surface area continuum solvation (MM-BGSA) method was used to estimate the free energy of binding of the small molecules with RSK2. …”
Publicado 2020
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1451por Sapata, Vítor Marques, Sapata, Diogo Marques, Araújo Gurgel, Julio, Medina Neto, Antônio, Ramos, Adilson Luiz“…All the wires presented higher forces at 3-mm deflection from 155 (±12.3) to 168.1 (±8) cN. …”
Publicado 2020
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1452por Lee, Seung Soo, Lee, Dong Hoon, Song, Won Hoon, Nam, Jong Kil, Han, Ji Yeon, Lee, Hyun Jung, Kim, Tae Un, Park, Sung-Woo“…PURPOSE: This study was conducted to compare the accuracy of bi-parametric magnetic resonance imaging (bpMRI) with high b-value (b=1,000 s/mm(2), b1000) diffusion-weighted imaging (DWI) to that of bpMRI with ultra-high b-value (b=1,800 s/mm(2), b1800) DWI to detect clinically significant prostate cancer (csPCa). …”
Publicado 2020
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1453por Schneider, Jakob, Ribeiro, Rui, Alfonso-Prieto, Mercedes, Carloni, Paolo, Giorgetti, Alejandro“…Here, we present the Hybrid MM/CG Webserver (mmcg.grs.kfa-juelich.de) that automatizes and speeds up the MM/CG simulation setup of hGPCR/ligand complexes. …”
Publicado 2020
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1454por Longo, E., Sancey, L., Flenner, S., Kubec, A., Bonnin, A., David, C., Müller, M., Greving, I.Enlace del recurso
Publicado 2020
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1455por Dimopoulos, Meletios A., Špička, Ivan, Quach, Hang, Oriol, Albert, Hájek, Roman, Garg, Mamta, Beksac, Meral, Bringhen, Sara, Katodritou, Eirini, Chng, Wee-Joo, Leleu, Xavier, Iida, Shinsuke, Mateos, María-Victoria, Morgan, Gareth, Vorog, Alexander, Labotka, Richard, Wang, Bingxia, Palumbo, Antonio, Lonial, Sagar“…PATIENTS AND METHODS: The phase III, double-blind, placebo-controlled TOURMALINE-MM4 study randomly assigned (3:2) patients with NDMM not undergoing ASCT who achieved better than or equal to partial response after 6-12 months of standard induction therapy to receive the oral proteasome inhibitor (PI) ixazomib or placebo on days 1, 8, and 15 of 28-day cycles as maintenance for 24 months. …”
Publicado 2020
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1456
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1457por Yu, Xiangyang, Zhang, Rusi, Zhang, Mengqi, Lin, Yongbin, Zhang, Xuewen, Wen, Yingsheng, Yang, Longjun, Huang, Zirui, Wang, Gongming, Zhao, Dechang, Gonzalez, Michel, Baste, Jean-Marc, Petersen, Rene Horsleben, Ng, Calvin S. H., Brunelli, Alessandro, Zheng, Lie, Zhang, Lanjun“…This study aimed to compare survival outcomes following lobectomy and segmental resection in patients with pathological T1cN0M0 (tumor size 21–30 mm) NSCLC. METHODS: Patients diagnosed between 1998 and 2016 with pathological stage IA NSCLC and with tumors measuring 21–30 mm were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. …”
Publicado 2021
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1458por Lee, Chan Joo, Ha, Jeong‐Ha, Kim, Jang Young, Kim, In‐Cheol, Ryu, Sung Kee, Rhee, Moo‐Yong, Lee, Ju‐Hee, Lee, Jung‐Hee, Lee, Hae‐Young, Ihm, Sang‐Hyun, Chung, Joong Wha, Choi, Jung Hyun, Shin, Jinho, Park, Sungha, Kario, Kazuomi“…We defined uncontrolled out‐of‐office BP as daytime BP ≥ 135/85 mmHg and/or home BP ≥ 135/85 mmHg. Among subjects with office BP < 140/90 mmHg and subjects with office BP < 130/80 mmHg, 66% and 55% had uncontrolled out‐of‐office BP, respectively. …”
Publicado 2020
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1459por Logie, Emilie, Chirumamilla, Chandra S., Perez-Novo, Claudina, Shaw, Priyanka, Declerck, Ken, Palagani, Ajay, Rangarajan, Savithri, Cuypers, Bart, De Neuter, Nicolas, Mobashar Hussain Urf Turabe, Fazil, Kumar Verma, Navin, Bogaerts, Annemie, Laukens, Kris, Offner, Fritz, Van Vlierberghe, Pieter, Van Ostade, Xaveer, Berghe, Wim Vanden“…ABSTRACT: Multiple myeloma (MM) is a hematological malignancy characterized by plasma cells’ uncontrolled growth. …”
Publicado 2021
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1460por Wu, Y.H. Andrew, Oba, Atsushi, Beaty, Laurel, Colborn, Kathryn L., Rodriguez Franco, Salvador, Harnke, Ben, Meguid, Cheryl, Negrini, Daniel, Valente, Roberto, Ahrendt, Steven, Schulick, Richard D., Del Chiaro, Marco“…Both MPD cutoffs of ≥5 mm and ≥10 mm were associated with malignancy (OR = 4.36 (95% CI: 2.82, 6.75) vs. …”
Publicado 2021
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