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147981por Towfighi, Amytis, Cheng, Eric M., Ayala-Rivera, Monica, McCreath, Heather, Sanossian, Nerses, Dutta, Tara, Mehta, Bijal, Bryg, Robert, Rao, Neal, Song, Shlee, Razmara, Ali, Ramirez, Magaly, Sivers-Teixeira, Theresa, Tran, Jamie, Mojarro-Huang, Elizabeth, Montoya, Ana, Corrales, Marilyn, Martinez, Beatrice, Willis, Phyllis, Macias, Mireya, Ibrahim, Nancy, Wu, Shinyi, Wacksman, Jeremy, Haber, Hilary, Richards, Adam, Barry, Frances, Hill, Valerie, Mittman, Brian, Cunningham, William, Liu, Honghu, Ganz, David A., Factor, Diane, Vickrey, Barbara G.“…The primary outcome is blood pressure (BP) control (systolic BP <130 mmHg) at 1 year. Secondary outcomes include: (1) mean change in systolic BP; (2) control of other vascular risk factors including lipids and hemoglobin A1c, (3) inflammation (C reactive protein [CRP]), (4) medication adherence, (5) lifestyle factors (smoking, diet, and physical activity), (6) estimated relative reduction in risk for recurrent stroke or myocardial infarction (MI), and (7) cost-effectiveness of the intervention versus usual care. …”
Publicado 2017
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147982“…The chromatographic separation was studied on an Ultimate™ XB-C(18) column (150 mm × 4.6 mmi.d., 3.5 μm) with a mobile phase composed of 0.5% aqueous acetic acid and acetonitrile using a gradient elution in 70 min. …”
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147983por Watabe, Tadashi, Kanai, Yasukazu, Ikeda, Hayato, Horitsugi, Genki, Matsunaga, Keiko, Kato, Hiroki, Isohashi, Kayako, Abe, Kohji, Shimosegawa, Eku, Hatazawa, Jun“…Multiple volumes of interest (1-mm diameter sphere) were placed on the co-registered (18)F-FMISO (3 h post injection) and functional (15)O-labelled gases PET images. …”
Publicado 2017
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147984por Dolling, David I., Goodall, Ruth L., Chirara, Michael, Hakim, James, Nkurunziza, Peter, Munderi, Paula, Eram, David, Tumukunde, Dinah, Spyer, Moira J., Gilks, Charles F., Kaleebu, Pontiano, Dunn, David T., Pillay, Deenan“…In multivariate analyses, female patients (HR = 0.79, 95% CI: 0.65–0.95; p = 0.02), older patients (HR = 0.73 per 10 years, 95% CI: 0.64–0.84; p < 0.0001) and patients with a higher pre-ART CD4 cell count (HR = 0.64 per 100 cells/mm(3), 95% CI: 0.54–0.75; p < 0.0001) had a lower incidence of virological failure after adjusting for adherence to ART. …”
Publicado 2017
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147985por Davies, Michael J., Merton, Katherine, Vijapurkar, Ujjwala, Yee, Jacqueline, Qiu, Rong“…METHODS: Analyses were based on pooled data from four 26-week, placebo-controlled, Phase 3 studies that evaluated canagliflozin 100 and 300 mg in patients with T2DM (N = 2313; mean HbA1c, 8.0%; body weight, 89 kg; systolic BP, 128 mmHg). Changes from baseline to week 26 in HbA1c, body weight, and systolic BP were assessed based on history of CV disease, history of hypertension, baseline statin use, and number of CV risk factors. …”
Publicado 2017
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147986por Beyaz, Salih, Güler, Ümit Özgür, Demir, Şenay, Pehlivan, Selcen, Çınar, Bekir Murat, Özkoç, Gürkan, Akpınar, Sercan“…Tunnel cross-sectional areas were also measured in mm2 using the same device on axial reconstructions. …”
Publicado 2017
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147987Comparison of methods for detecting asymptomatic malaria infections in the China–Myanmar border areapor Zhao, Yonghong, Zhao, Yan, Lv, Yanmin, Liu, Fei, Wang, Qinghui, Li, Peipei, Zhao, Zhenjun, Liu, Yingjie, Cui, Liwang, Fan, Qi, Cao, Yaming“…For nested PCR and RT-PCR, parasite DNA and total RNA were extracted from ~100 µL of blood, whereas RNA used for CLIP-PCR was from a 3 mm disk of dried blood filter paper. The sensitivity and specificity of these methods were compared with those of conventional light microscopy. …”
Publicado 2017
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147988por Hur, Woojune, Lee, Hoon Young, Min, Hye Sook, Wufuer, Maierdanjiang, Lee, Chang-won, Hur, Ji An, Kim, Sang Hyon, Kim, Byeung Kyu, Choi, Tae Hyun“…For in-vivo analysis, we injected various cell types into balb/c nude mouse skin carrying a 10-mm punch wound, and observed a significantly positive wound healing effect in this full-thickness excision model with F-CM-treated hADSCs rather than with untreated hADSCs or the PBS injected group. …”
Publicado 2017
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147989por Norman, Jane Elizabeth, Marlow, Neil, Messow, Claudia-Martina, Shennan, Andrew, Bennett, Phillip R, Thornton, Steven, Robson, Stephen C, McConnachie, Alex, Petrou, Stavros, Sebire, Neil J, Lavender, Tina, Whyte, Sonia, Norrie, John“…METHODS: We did a double-blind, randomised, placebo-controlled trial of vaginal progesterone, 200 mg daily taken from 22–24 to 34 weeks of gestation, on pregnancy and infant outcomes in women at risk of preterm birth (because of previous spontaneous birth at ≤34 weeks and 0 days of gestation, or a cervical length ≤25 mm, or because of a positive fetal fibronectin test combined with other clinical risk factors for preterm birth [any one of a history in a previous pregnancy of preterm birth, second trimester loss, preterm premature fetal membrane rupture, or a history of a cervical procedure to treat abnormal smears]). …”
Publicado 2016
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147990por De Vecchis, Renato, Cesaro, Arturo, Ariano, Carmelina, Giasi, Anna, Cioppa, Carmela“…For patients with HFREF, PDE5 inhibitors caused a non-significant reduction in mPAP, while PASP was significantly reduced (MD: -11.52 mm Hg; 95% CI: -15.56 to -7.49; P < 0.001). By contrast, in the RCTs of patients with CHF with preserved left ventricular ejection fraction (HFpEF, n = 373), no benefit ensued from PDE5 inhibitor use regarding all of the investigated clinical, ergospirometric or hemodynamic endpoints. …”
Publicado 2017
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147991por Yamamoto, Tokihiro, Kent, Michael S., Wisner, Erik R., Johnson, Lynelle R., Stern, Joshua A., Qi, Lihong, Fujita, Yukio, Boone, John M.“…RESULTS: The mean TRE (and standard deviation) was 0.6 ± 0.7 mm (smaller than the voxel dimension) for DIR between pre contrast and postcontrast end-inspiratory CT image data sets. …”
Publicado 2016
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147992“…The mean instrumented laxity was 1.8 mm in the acute and 2.0 in the delayed group. There were no positive pivot shift in the acute group and 6 patients with grade 1 or not possible to perform in the delayed group (p=0.039). …”
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147993por Mao, Alice Yuqing, Chen, Connie, Magana, Candy, Caballero Barajas, Karla, Olayiwola, J Nwando“…Among 151 intervention participants with blood pressure data, 112 (74.2%) had a baseline blood pressure that was above the goal (systolic blood pressure >120 mmHg); 55 out of 112 (49.1%) participants improved their blood pressure at 4 months by an entire hypertensive stage—as defined by the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. …”
Publicado 2017
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147994por Coffie, Patrick A., Tchounga, Boris K., Bado, Guillaume, Kabran, Mathieu, Minta, Daouda K., Wandeler, Gilles, Gottlieb, Geoffrey S., Dabis, François, Eholie, Serge P., Ekouevi, Didier K.“…At time of sampling, 555 (70.2%) were on ART and median CD4+ cell count was 472/mm(3) (inter-quartile range [IQR]: IQR: 294–644). …”
Publicado 2017
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147995por Uppugunduri, Chakradhara Rao S., Storelli, Flavia, Mlakar, Vid, Huezo-Diaz Curtis, Patricia, Rezgui, Aziz, Théorêt, Yves, Marino, Denis, Doffey-Lazeyras, Fabienne, Chalandon, Yves, Bader, Peter, Daali, Youssef, Bittencourt, Henrique, Krajinovic, Maja, Ansari, Marc“…Ac was found to be toxic to HUC cells at lower concentrations (33 μM), Su was not toxic to HUC cells at concentrations below 1 mM and did not affect CYP function in HepaRG cells. …”
Publicado 2017
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147996por Backx, Evelien M. P., Hangelbroek, Roland, Snijders, Tim, Verscheijden, Marie-Louise, Verdijk, Lex B., de Groot, Lisette C. P. G. M., van Loon, Luc J. C.“…Quadriceps muscle CSA had declined by 465 ± 59 and 425 ± 69 mm(2) (p < 0.01) in the creatine and placebo group, respectively, with no differences between groups (p = 0.76). …”
Publicado 2017
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147997por Winbo, Annika, Stattin, Eva-Lena, Westin, Ida Maria, Norberg, Anna, Persson, Johan, Jensen, Steen M., Rydberg, Annika“…Mean QTc was obtained by repeated manual measurement (preferably in lead II) by one observer using coded 50 mm/s standard 12-lead ECGs. RESULTS: A substantial variance in mean QTc was seen in genotype positives 476 ± 36 ms (Y111C 483 ± 34 ms; R518* 462 ± 34 ms) and genotype negatives 433 ± 24 ms. …”
Publicado 2017
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147998por Greer, Liana, Pannullo, Susan C., Smith, Andrew W, Taube, Shoshana, Yondorf, Menachem Z, Parashar, Bhupesh, Trichter, Samuel, Nedialkova, Lucy, Sabbas, Albert, Christos, Paul, Wernicke, A. Gabriella“…HFRT was given every other weekday for two weeks, in a total of six fractions (6 × 6 Gy to contrast-enhancing tumor +5 mm and 6 × 4 Gy to fluid-attenuated inversion recovery (FLAIR) +2 cm) with concurrent TMZ (75 mg/m2 daily), followed by adjuvant TMZ (150-200 mg/m2 in 5/28 days). …”
Publicado 2017
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147999por Barnard, Ed B. G., Manning, James E., Smith, Jason E., Rall, Jason M., Cox, Jennifer M., Ross, James D.“…TCA was induced by laparoscopic liver lobe resection combined with arterial catheter blood withdrawal to achieve a sustained systolic blood pressure <10 mmHg, cardiac arrest. After 3 min of arrest, swine were allocated to one of three interventions: (1) REBOA plus 4 units of IV fresh whole blood (FWB), (2) SAAP with oxygenated lactated Ringer’s (LR), 1,600 mL/2 min, or (3) SAAP with oxygenated FWB 1,600 mL/2 min. …”
Publicado 2017
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148000por Xerogeanes, John W., Godfrey, William, Gebrelul, Aaron, Premkumar, Ajay, Mignemi, Danielle, Gottschalk, Michael Brandon, Dalwadi, Poonam, Fellow, Research, Slone, Harris“…The percentage of patients with ≤3 mm side-to-side difference on KT-1000 arthrometer testing at 6-weeks, 3-months, and 6-months was found to be 97%, 96%, and 93%, respectively. …”
Publicado 2017
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