“…Biochemical evaluation demonstrated normal potassium level 3.7 (3.5-5.3 mmol/dL) and aldosterone 8ng/mL (<28), non-suppressed cortisol 7.8mcg/dL after dexamethasone 1mg given the night prior, but Cushing’s Disease was ruled out by normal salivary cortisol 0.08 mcg/dL (nl 0.04-0.56 mcg/dL) and urine free cortisol 22.8 mcg/ 24h (nl 4-50 mcg/24h), and further testing revealed elevated metanephrines and catecholamines during 24 hour urine collection, Epinephrine 129 mcg/24h (nl 2-24 mcg/24h), Metanephrine 7121 mcg/24h (nl 90-315 mcg/24h) and Normetanephrine 2078 mcg/ 24h (nl 122-676 mcg/24h).Repeat CT scan again showed an indeterminate 5.4 x 3.8 x 5.5 cm right adrenal mass, a 6.9mm lipid-rich left adrenal adenoma, and left adrenal gland hyperplasia. …”
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“…MRI pituitary with contrast done 11 yrs. earlier showed a 1.5 mm focus of relative delayed and nonenhancement between anterior and posterior pituitary gland, as well as an overall volume of the pituitary smaller than expected for age. …”
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“…Thyroid ultrasound revealed a 9mm hypoechoic lesion in the right inferior lobe with polar artery. …”
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“…Brain MRIs done between 2019 and 2020 showed stable 13x8 mm residual pituitary mass with postoperative changes. …”
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“…In 41/45 cycles, there was morphological (antral follicle diameter > 10 mm observed ultrasonographically, n=22) and/or endocrinological (LH surge, n=38) evidence for the presence of a dominant follicle. …”
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“…Introduction: Primary bilateral macronodular adrenal hyperplasia (PBMA) is an uncommon cause of endogenous Cushing's syndrome, defined as both adrenal glands with multiple nodules > 10mm in diameter. It often presents as incidentally found, bilateral, macronodular adrenal glands in patients between 40-60 years of age, frequently with only mild cortisol elevation. …”
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“…Thyroid and parathyroid sonography demonstrated a solid hypoechoic nodule in the right thyroid lobe, 12x10x11mm, with smooth margins, no calcifications, classified as ACR TI-RADS T4. …”
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“…This led to a further workup including a PET/CT scan, which showed a hyper metabolic 6 mm left supraclavicular lymph node. Needle biopsy of this lymph node disclosed metastatic PTC. …”
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“…Spatial frequency domain imaging (SFDI) is a novel non-invasive optical technology that can detect and quantify microvascular disease of the foot by measuring the amount of hemoglobin(HbT1) in the capillaries of the superficial dermis up to 1-2mm deep and oxygenation (StO2) in the dermal micro-circulation. …”
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“…GnRH therapy led to increase in BMI (28 ± 1 vs 31 ± 2 kg.m(2), p=0.006), though no difference was observed in SBP (126 ± 2 vs 120 ± 2 mmHg, p=ns), total Cholesterol (170 ± 7 vs 171 ± 8 mg/dL), HDL Cholesterol (45 ± 2 vs. 46 ± 2 mg/dL), LDL Cholesterol (98 ± 7 vs 99 ± 5 mg/dL) before and after treatment. …”
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“…Vital signs on admission revealed heart rate of 100 beats/min, respiratory rate of 16 breaths/min, blood pressure of 131/66 mmHg, temperature of 97.5°F and oxygen saturation of 98% on room air. …”
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“…Two-month post-surgical MRI showed residual 8mm lesion. Active surveillance showed regrowth of sellar lesion to 1.8 cm with optic chiasm compression ten months following EEA. …”
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“…Laboratory evaluation showed normal serum calcium (9.5 mg/dl), albumin (4.1g/dl), Vit D 25-OH (36 mg/ml), bone specific alkaline phosphatase of 22.7 U/L and urine NTx of 23 nm BCE/mm creatinine. Bone density (BMD) in January 2022 showed lumbar spine (LS) BMD of 0.613 g/cm2 (T-score −4.7) and a total hip BMD of 0.575 g/cm2 (T-score −3.4). …”
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“…I.A. Rivera Nazario: None. M.M. Mangual Garcia: None. Cortisol is released from the adrenal glands and works through the glucocorticoid receptor to mediate stress, metabolism, immune and inflammatory processes. …”
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“…During admission she remained with tachycardia (heart rate >100 beats per minute) and elevated systolic blood pressure (>120 mm Hg). Family confirmed tachycardia and mild exophthalmos started recently before admission. …”
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“…Disclosure: M.M. Eid: None. T. Zahra: None. J. Vargas-Jerez: None. …”
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“…Admission labs revealed ionized calcium 0.78 (1.15 - 1.30 MM/L) , serum Ca 6.2 (Albumin 4.3). PTH elevated to 364. …”
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“…MAP was significantly higher in female off. from HAF-WD compared to female off. from CON-CD and HAF-CD (113 ± 3 vs 104 ± 2 and 103 ± 5 mmHg, p<0.05). Yet, MAP was similar between female off. from CON-WD, CON-CD and HAF-WD. …”
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“…Systolic blood pressure of transgender group was higher than cisgender group, 113.45 (11.09) versus 101.18 (8.08) mmHg, p<0.008. Other metabolic parameters such as fasting glucose, HOMA-IR, lipids, and diastolic blood pressure did not differ between groups. …”
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“…The patient’s vital signs were as follows: blood pressure: elevated to 133/79 mmHg, heart rate: 75 beats per minute, temperature: 36.7 C, and respiratory rate: 12 breaths per minute. …”
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