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149501por Eggermont, Alexander M. M., Kicinski, Michal, Blank, Christian U., Mandala, Mario, Long, Georgina V., Atkinson, Victoria, Dalle, Stéphane, Haydon, Andrew, Khattak, Adnan, Carlino, Matteo S., Sandhu, Shahneen, Larkin, James, Puig, Susana, Ascierto, Paolo A., Rutkowski, Piotr, Schadendorf, Dirk, Koornstra, Rutger, Hernandez-Aya, Leonel, Di Giacomo, Anna Maria, van den Eertwegh, Alfonsus J. M., Grob, Jean-Jacques, Gutzmer, Ralf, Jamal, Rahima, Lorigan, Paul C., Krepler, Clemens, Ibrahim, Nageatte, Marreaud, Sandrine, van Akkooi, Alexander, Robert, Caroline, Suciu, Stefan“…Eligible patients were adults 18 years and older with complete resection of cutaneous melanoma metastatic to lymph nodes, classified with stage IIIA (at least 1 micrometastasis measuring >1 mm in greatest diameter), IIIB, or IIIC (without in-transit metastasis) cancer. …”
Publicado 2020
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149502por Apter, Susanna, Ebner, Thomas, Freour, Thomas, Guns, Yves, Kovacic, Borut, Le Clef, Nathalie, Marques, Monica, Meseguer, Marcos, Montjean, Debbie, Sfontouris, Ioannis, Sturmey, Roger, Coticchio, Giovanni“…T.F. received consulting fees from Vitrolife and Laboratoires Genévrier, speakers’ fees from Merck Serono, Gedeon Richter, MSD and Ferring and research grants from Gedeon Richter and MSD. M.M. received sponsorship from Merck. M.M.E. received speakers’ fees from Merck, Ferring and MSD. …”
Publicado 2020
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149503por Aide, Nicolas, Tainturier, Laure-Eugénie, Nganoa, Cathy, Houdu, Benjamin, Kammerer, Jennifer, Galais, Marie-Pierre, Ciappuccini, Renaud, Lasnon, Charline“…A single nuclear medicine physician visually and quantitatively analyzed anal canal uptake (SUV(max_EARL)) and assessed visual rectal content (air, feces, or both) and the largest rectal diameter (mm). RESULTS: Six hundred and thirteen patients were included (sex ratio F/M = 0.99) and 545 (89%) questionnaires were entirely completed. …”
Publicado 2020
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149504por Cao, Bin, Wang, Yeming, Wen, Danning, Liu, Wen, Wang, Jingli, Fan, Guohui, Ruan, Lianguo, Song, Bin, Cai, Yanping, Wei, Ming, Li, Xingwang, Xia, Jiaan, Chen, Nanshan, Xiang, Jie, Yu, Ting, Bai, Tao, Xie, Xuelei, Zhang, Li, Li, Caihong, Yuan, Ye, Chen, Hua, Li, Huadong, Huang, Hanping, Tu, Shengjing, Gong, Fengyun, Liu, Ying, Wei, Yuan, Dong, Chongya, Zhou, Fei, Gu, Xiaoying, Xu, Jiuyang, Liu, Zhibo, Zhang, Yi, Li, Hui, Shang, Lianhan, Wang, Ke, Li, Kunxia, Zhou, Xia, Dong, Xuan, Qu, Zhaohui, Lu, Sixia, Hu, Xujuan, Ruan, Shunan, Luo, Shanshan, Wu, Jing, Peng, Lu, Cheng, Fang, Pan, Lihong, Zou, Jun, Jia, Chunmin, Wang, Juan, Liu, Xia, Wang, Shuzhen, Wu, Xudong, Ge, Qin, He, Jing, Zhan, Haiyan, Qiu, Fang, Guo, Li, Huang, Chaolin, Jaki, Thomas, Hayden, Frederick G., Horby, Peter W., Zhang, Dingyu, Wang, Chen“…METHODS: We conducted a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2 infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao(2)) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxygen (Pao(2)) to the fraction of inspired oxygen (Fio(2)) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir–ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. …”
Publicado 2020
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149505“…Methods: This institutional review board–approved descriptive survey of resident and attending physicians in accredited emergency medicine residency training programs in New York City used a previously tested, tracheal simulation model with a 7.5-mm endotracheal tube with a high-volume low-pressure cuff (Mallinkrodt, St. …”
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149506por Bustin, Aurélien, Rashid, Imran, Cruz, Gastao, Hajhosseiny, Reza, Correia, Teresa, Neji, Radhouene, Rajani, Ronak, Ismail, Tevfik F., Botnar, René M., Prieto, Claudia“…Ten healthy subjects and eight patients with suspected coronary artery disease underwent 4–5-fold accelerated free-breathing whole-heart CMRA with 0.9 mm(3) isotropic resolution. Vessel sharpness, vessel length and image quality obtained with the proposed non-rigid (NR) PROST approach were compared against translational correction only (TC-PROST) and a previously proposed NR motion-compensated technique (non-rigid SENSE) in healthy subjects. …”
Publicado 2020
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149507por Ormazabal, Paulina, Sanhueza, Sofía, Herrera, Karin, Cifuentes, Mariana, Varì, Rosaria, Scazzocchio, Beatrice, Masella, Roberta, Paredes, Adrián, Morales, Glauco“…Cells were exposed for 48 h to 1 mM OA/PA (2:1) in the presence or not of 0.01 or 10 μg/mL HEL. …”
Publicado 2020
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149508por Teguh, Dian A, Nustad, Jordan L, Craven, Amanda E, Brooks, Daniel J, Arlt, Heike, Lanske, Beate, Bouxsein, Mary L“…Femurs were mechanically tested to failure in 3-point bending to determine ultimate load (N) and stiffness (N/mm). Treatment effects were evaluated using 2-way ANOVA. …”
Publicado 2020
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149509por Vigevano, Francesca, Chen, Rui, Colleluori, Georgia, Auetumrongsawat, Vimlin, Gregori, Giulia, Villareal, Dennis, Armamento-Villareal, Reina“…F. load (13.3 ± 2.1 vs 14.5 ± 2.3 kN, p= 0.02) and stiffness (24.7± 4.2 vs 27 ± 4.6 kN/mm, p=0.02) were reduced in men with T2DM relative to men without T2DM, respectively. …”
Publicado 2020
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149510“…A contrast-enhanced pituitary-protocoled MRI was notable for a moderately flattened sella (pituitary 3.5 mm in height) and absence of usual T1 bright signal in the posterior lobe. …”
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149511“…His vital signs were notable for HR of 86 bpm and BP of 112/75 mmHg. Labs at admission were remarkable for an uncorrected Ca of 16.1 (8.8-10.3 ng/mL), a phosphorus (Phos) level of 3.3 mg/dL (2.5-4.5 mg/dL), a PTH level of 11 pg/mL (15-65 pg/mL), PTHrP level of 134 pg/mL (14-27 pg/mL), a 25 OH vit D level of 11 ng/mL (30-100 ng/mL), and a BUN/Cr and GFR of 34/2.38 (8-22 mg/dL/0.5-1.3 mg/dL) and 32 ml/min/m2. …”
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149512“…MRI pituitary revealed an 18.1 x 13.8 x 15.8 mm hypothalamic mass with signal intensity alteration in the optic pathway. …”
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149513por El-Naghy, Zeyad, Krasnow, Nicholas Andrew, Haigney, James, Patale, Tara, McGuirk, Liam, Alexandrov, Alice, Gold, Steven, Tenner, Michael, Noto, Richard A“…PTs who underwent multiple high resolution post-contrast MRIs (1mm slices) were subjects of this study. PTs with additional MRI abnormalities were excluded. …”
Publicado 2020
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149514“…He also had hypertension (156/87 mmHg), dyslipidemia (T-cholesterol 236 mg/dL, LDL-C 175 mg/dL) and insulin resistance (AC glucose 87 mg/dL, insulin 23.5 μU/mL, HOMA-IR 5.0, Hb1Ac 5.6%). …”
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149515“…Similarly, HUVEC acutely exposed to high glucose (HG, 25 mM) activated both canonical (IκB-α degradation, normal vs. …”
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149516por Ebbehoj, Andreas, Kaur, Ravinder J, Li, Dingfeng, Singh, Sumitabh, Zhang, Catherine, Atkinson, Elizabeth J, Achenbach, Sara J, Rocca, Walter A, Khosla, Sundeep, Bancos, Irina“…Median tumor size was 15 mm (range 5–255), and 184 (14%) of patients had bilateral tumors. …”
Publicado 2020
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149517por Rokx, Casper, Borjas Howard, Jaime F., Smit, Colette, Wit, Ferdinand W., Pieterman, Elise D., Reiss, Peter, Cannegieter, Suzanne C., Lijfering, Willem M., Meijer, Karina, Bierman, Wouter, Tichelaar, Vladimir, Rijnders, Bart J. A.“…VTE recurred less frequently in PWH who were more immunodeficient at the first VTE, marked by a better CD4+ T-cell recovery on antiretroviral therapy and during anticoagulant therapy for the first VTE (adjusted HR: 0.81 per 100 cells/mm(3) increase, 95% CI 0.67–0.97, p = 0.02). Sensitivity analyses addressing potential sources of bias confirmed our principal analyses. …”
Publicado 2020
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149518por Llach, Cristian, Fortea, Adriana, Valli, Isabel, Mendez, Iria, Lera, Sara, Arbelo, Nestor, Ilzarbe, Lidia, Baeza, Inmaculada, Castro-Fornieles, Josefina, Romero, Soledad, Sugranyes, Gisela“…RESULTS: Between-group analyses showed smaller CTH in a cluster in the left medial orbitofrontal cortex (cluster size= 1142.58 mm2) in PSBD relative to NPSBD (x, y, z: 25.63, 89.61, -42.74; p=0.002). …”
Publicado 2020
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149519por Sosso, Samuel Martin, Tchouaket, Michel Carlos Tommo, Fokam, Joseph, Simo, Rachel Kamgaing, Torimiro, Judith, Tiga, Aline, Lobe, Elise Elong, Ambada, Georgia, Nange, Achille, Semengue, Ezechiel Ngoufack Jagni, Nka, Alex Durand, Tala, Valère, Chenwi, Collins, Abba, Aissatou, Ka’e, Aude Christelle, Yagai, Bouba, Colizzi, Vittorio, Ndjolo, Alexis“…RESULTS: Globally, mean age was 37 ± 3 years; median CD4-count for HIV+ was 414 cells/mm(3) [IQR: 264.75–588] and median viremia was 50 RNA copies/mL [IQR: < 40–8288]. …”
Publicado 2020
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149520por Ippolito, Davide, Drago, Silvia Girolama, Pecorelli, Anna, Maino, Cesare, Querques, Giulia, Mariani, Ilaria, Franzesi, Cammillo Talei, Sironi, Sandro“…Concerning the time-intensity curves, the AUC at MR2 showed significant difference (P = 0.03) between responders and non-responders [AUC (mm(2) × 10(-3)) 121 ± 50 vs 258 ± 86], with lower AUC values of the tumor tissue in responders compared to non-responders. …”
Publicado 2020
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