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149601“…CONCLUSIONS: The authors conclude that according to literature searches from previous studies, the optimal 3-HPMA analysis method in urine after cyclophosphamide administration using LC-MS/MS is using triple quadrupole LC-MS/MS; source of positive ion electrospray ionization (ESI); mobile phase combination of 0.1% formic acid in water (A) - 0.1% formic acid in acetonitrile (90:10 v/v) (B); the Acquity® BEH C18 column (2.1 × 100 mm; 1.7 μm); injection volume of 10 μl; flow rate of 0.2 ml/minute; gradient elution method. …”
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149602por Jadhav, Uday, Mohanan, Padhinhare P., Almeida, Alan Fernandes, Abraham, Georgi, Khan, Mohammed Yunus, Gaurav, Kumar, Mane, Amey, Vikas, Seema, Jain, Madhur, Meel, Bhavesh“…At the end of the study, the average dose of amlodipine was 7.25 mg, and the average reduction in SBP and DBP per mg dose was 1.54 and 0.57 mmHg. The corresponding numbers for the other CCBs were as follows: cilnidipine, 14.28 mg, 0.26 and 0.01; benidipine, 5.71 mg, 0.41 and 0.11; azelnidipine, 15.88 mg, 0.13 and 0.06. …”
Publicado 2021
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149603Multi-infusion with integrated multiple pressure sensing allows earlier detection of line occlusionspor Doesburg, Frank, Oelen, Roy, Renes, Maurits H., Lourenço, Pedro M., Touw, Daan J., Nijsten, Maarten W.“…Each run consisted of 10 min of non-occluded infusion followed by a period of occluded infusion of 10 min or until a conventional occlusion alarm at 400 mmHg occurred. The first algorithm based on binary logistic regression attempts to detect occlusions based on the pump’s administration rate Q(t) and pressure sensor readings P(t). …”
Publicado 2021
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149604por Moreira, Vinícius Eduardo, Veroneze, Renata, Teixeira, Alípio dos Reis, Campos, Lorena Duarte, Lino, Lais Fernanda Lopes, Santos, Gabryele Almeida, Silva, Bruno Alexander Nunes, Campos, Paulo Henrique Reis Furtado“…Piau crossbred pigs had greater BF (+7.2 mm; p < 0.01) than commercial pigs. Regardless of the genetic group, exposure of pigs to HT resulted in decreased ADFI (−372 g/day; p < 0.01), ADG (−185 g/day; p < 0.01), and a higher FCR (+0.48 g/g; p = 0.01). …”
Publicado 2021
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149605por Kotani, Yuki, Yoshida, Takuo, Kumasawa, Junji, Kamei, Jun, Taguchi, Akihisa, Kido, Koji, Yamaguchi, Naoki, Kariya, Takayuki, Nakasone, Masato, Mikami, Noriko, Koga, Takahiro, Nakayama, Izumi, Shibata, Mami, Yoshida, Tomonao, Nashiki, Hiroshi, Karatsu, Shinsuke, Nogi, Kazutaka, Tokuhira, Natsuko, Izawa, Junichi“…Among exploratory exposure variables, time-weighted-average CVP, time-weighted-average MPP, and time spent with MPP < 60 mmHg were associated with AKI progression (OR: 1.12, 95% CI 1.05–1.20; OR: 0.97, 95% CI 0.94–0.99; OR: 1.03, 95% CI 1.00–1.06, respectively). …”
Publicado 2021
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149606por Song, Lili, Hu, Xin, Ma, Lu, Chen, Xiaoying, Ouyang, Menglu, Billot, Laurent, Li, Qiang, Muñoz-Venturelli, Paula, Abanto, Carlos, Pontes-Neto, Octavio Marques, Antonio, Arauz, Wasay, Mohammad, Silva, Asita de, Thang, Nguyen Huy, Pandian, Jeyaraj Durai, Wahab, Kolawole Wasiu, You, Chao, Anderson, Craig S.“…After a control phase, each hospital implements the intervention (intensive BP lowering, target systolic < 140 mmHg; glucose control, target 6.1–7.8 mmol/L and 7.8–10.0 mmol/L in those without and with diabetes mellitus, respectively; anti-pyrexia treatment to target body temperature ≤ 37.5 °C; and reversal of anticoagulation, target international normalized ratio < 1.5 within 1 h). …”
Publicado 2021
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149607“…RESULTS: We found strong evidence of an association between low THRα-2 and unfavorable tumor characteristics, including estrogen receptor negativity: OR 4.04 (95% CI 2.28–7.15) and tumor size > 20–50 mm: OR 2.20 (95% CI 1.39–3.49). We found evidence of increased breast cancer-specific mortality for women with low THRα-2, HR 1.38 (95% CI 0.96–1.99), which remained after adjusting for age at diagnosis, HR 1.48 (95% CI 1.03–2.14), but not after adjusting for relevant prognostic factors, HR 0.98 (95% CI 0.66–1.45). …”
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149608por Bongiovanni, Filippo, Grieco, Domenico Luca, Anzellotti, Gian Marco, Menga, Luca Salvatore, Michi, Teresa, Cesarano, Melania, Raggi, Valeria, De Bartolomeo, Cecilia, Mura, Benedetta, Mercurio, Giovanna, D’Arrigo, Sonia, Bello, Giuseppe, Maviglia, Riccardo, Pennisi, Mariano Alberto, Antonelli, Massimo“…METHODS: Twenty patients with acute hypoxemic respiratory failure (PaO(2)/FiO(2) < 300 mmHg) underwent consecutive 1-h periods of helmet NIV (PEEP 12 cmH(2)O, pressure support 12 cmH(2)O) with four humidification settings, applied in a random order: double-tube circuit with HHs and temperature set at 34 °C (HH34) and 37 °C (HH37); Y-piece circuit with HME; double-tube circuit with no humidification (NoH). …”
Publicado 2021
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149609por Evaristi, Maria Francesca, Poirier, Bruno, Chénedé, Xavier, Lefebvre, Anne-Marie, Roccon, Alain, Gillot, Florence, Beeské, Sandra, Corbier, Alain, Pruniaux-Harnist, Marie-Pierre, Janiak, Philip, Parkar, Ashfaq A.“…In aged animals, SAR247799 reduced cardiac hypertrophy (g/mm mean ± SEM of heart weight/tibia length 0.053 ± 0.001 for Ob-ZSF1-CTRL vs 0.046 ± 0.002 for Ob-ZSF1-SAR247799 p<0.01, Le-ZSF1-CTRL 0.035 ± 0.001) and myocardial perivascular collagen content (p<0.001), independently of any changes in microvascular density. …”
Publicado 2022
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149610por Vidanage, Dinithi, Prathapan, Shamini, Hettiarachchi, Priyadarshika, Wasalathanthri, Sudharshani“…RESULTS: Aerobic exercise group showed significantly increased ratings (mm) for higher sucrose concentrations at 3 months (mean difference for 2.02M; +6.63±2.50, p=0.048 and for 0.64M; +7.26±2.76, p=0.026) and at 6 months (mean difference for 0.64M; +7.79±4.49, p= 0.044) compared to baseline and also when compared to controls (mean difference for 2.02M between baseline and 3 months; intervention: +6.63±2.50, control: -4.01±1.79, p=0.02 and between baseline and 6 months for 2.02M; intervention: +3.15±0.57, control: -7.96±0.40, p=0.022 and for 0.64M; intervention: +7.79±4.49, control: -8.98±0.99, p=0.003). …”
Publicado 2022
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149611por Masina, Riccardo, Ansaripour, Ali, Beneš, Vladimír, Berhouma, Moncef, Choque-Velasquez, Joham, Eide, Per Kristian, Fedorko, Stepan, Fleck, Steffen, Hernesniemi, Juha, Koziarski, Andrzej, Májovský, Martin, Podgorski, Andrzej, Schroeder, Henry, Teo, Charles, Unterberg, Andreas W., Yeung, Jacky T., Kolias, Angelos, Santarius, Thomas“…Demographics: Mean age was 29 (range: 4–63) with 77% females. Mean cyst size was 15 mm (5–35). Supracerebellar-infratentorial approach was adopted in 90% of cases, occipital-transtentorial in 9%, and was not reported in 1%. …”
Publicado 2021
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149612por Grieco, Domenico Luca, Maggiore, Salvatore Maurizio, Bellani, Giacomo, Spadaro, Savino, Spinelli, Elena, Tonetti, Tommaso, Menga, Luca S., Pozzi, Marco, Battaglini, Denise, Di Mussi, Rosa, Bruni, Andrea, De Gaetano, Andrea, Iovino, Carmine Giovanni, Brioni, Matteo, Mojoli, Francesco, Foti, Giuseppe, Volta, Carlo Aberto, Pelosi, Paolo, Navalesi, Paolo, Grasso, Salvatore, Ranieri, V. Marco, Antonelli, Massimo“…METHODS: IPERPEEP is an open-label, multicenter, randomized trial that will be conducted in 10 intensive care units in Italy and will enroll 132 ARDS patients showing PaO(2)/FiO(2) ratio ≤ 150 mmHg within 24 h from endotracheal intubation while on mechanical ventilation with PEEP 5 cmH(2)O. …”
Publicado 2022
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149613por Oncina-Cánovas, Alejandro, Vioque, Jesús, González-Palacios, Sandra, Martínez-González, Miguel Ángel, Salas-Salvadó, Jordi, Corella, Dolores, Zomeño, Dolores, Martínez, J. Alfredo, Alonso-Gómez, Ángel M., Wärnberg, Julia, Romaguera, Dora, López-Miranda, José, Estruch, Ramon, Bernal-Lopez, Rosa M., Lapetra, José, Serra-Majem, J. Luís, Bueno-Cavanillas, Aurora, Tur, Josep A., Martín-Sánchez, Vicente, Pintó, Xavier, Delgado-Rodríguez, Miguel, Matía-Martín, Pilar, Vidal, Josep, Vázquez, Clotilde, Daimiel, Lidia, Ros, Emili, Toledo, Estefanía, Babio, Nancy, Sorli, Jose V., Schröder, Helmut, Zulet, María Angeles, Sorto-Sánchez, Carolina, Barón-López, Francisco Javier, Compañ-Gabucio, Laura, Morey, Marga, García-Ríos, Antonio, Casas, Rosa, Gómez-Pérez, Ana María, Santos-Lozano, José Manuel, Vázquez-Ruiz, Zenaida, Nishi, Stephanie K., Asensio, Eva M., Soldevila, Núria, Abete, Itziar, Goicolea-Güemez, Leire, Buil-Cosiales, Pilar, García-Gavilán, Jesús F., Canals, Erik, Torres-Collado, Laura, García-de-la-Hera, Manuela“…Multivariable-adjusted robust linear regression using MM-type estimator was used to assess the association between PVG food patterns and the standardized Metabolic Syndrome score (MetS z-score), a composed index that has been previously used to ascertain the cardiometabolic risk, adjusting for potential confounders. …”
Publicado 2021
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149614por Inokuchi, Yasuhiro, Ishida, Ayaka, Hayashi, Kei, Kaneta, Yoshihiro, Watanabe, Hayato, Kano, Kazuki, Furuta, Mitsuhiro, Takahashi, Kosuke, Fujikawa, Hirohito, Yamada, Takanobu, Yamamoto, Kouji, Machida, Nozomu, Ogata, Takashi, Oshima, Takashi, Maeda, Shin“…A dissection incision > 40 mm, lesions associated with depressions, and lesions with ulcers were risk factors for post-ESD bleeding, and location of the lesion in the upper third of the stomach was a risk factor for perforation in elderly patients (P < 0.05). …”
Publicado 2022
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149615por de Cesar Netto, Cesar, Mansur, Nacime S., Lalevée, Matthieu, Lintz, Francois, Buedts, Kristian, Goldberg, Andrew J., Deland, Jonathan T., Femino, John E., Anderson, Donald D., Dibbern, Kevin N.“…Joint coverage was defined as the percentage of articular space where DMs were <5 mm. Coverage Maps (CM) were built highlighting areas of adequate joint interaction (blue), joint subluxation (pink), and impingement (red). …”
Publicado 2022
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149616por Breitsprecher, Tabita, Dhanasingh, Anandhan, Schulze, Marko, Kipp, Markus, Dakah, Rami Abu, Oberhoffner, Tobias, Dau, Michael, Frerich, Bernhard, Weber, Marc-André, Langner, Soenke, Mlynski, Robert, Weiss, Nora M.“…Temporal bones were implanted with a 31.5-mm CI electrode and measurements were compared to a reference based on the CI electrode insertion angle measured by radiographs in Stenvers projection (CDL(reference)). …”
Publicado 2021
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149617por Sardanelli, Francesco, Trimboli, Rubina M., Houssami, Nehmat, Gilbert, Fiona J., Helbich, Thomas H., Álvarez Benito, Marina, Balleyguier, Corinne, Bazzocchi, Massimo, Bult, Peter, Calabrese, Massimo, Camps Herrero, Julia, Cartia, Francesco, Cassano, Enrico, Clauser, Paola, Cozzi, Andrea, de Andrade, Danúbia A., de Lima Docema, Marcos F., Depretto, Catherine, Dominelli, Valeria, Forrai, Gábor, Girometti, Rossano, Harms, Steven E., Hilborne, Sarah, Ienzi, Raffaele, Lobbes, Marc B. I., Losio, Claudio, Mann, Ritse M., Montemezzi, Stefania, Obdeijn, Inge-Marie, Ozcan, Umit A., Pediconi, Federica, Pinker, Katja, Preibsch, Heike, Raya Povedano, José L., Sacchetto, Daniela, Scaperrotta, Gianfranco P., Schiaffino, Simone, Schlooz, Margrethe, Szabó, Botond K., Taylor, Donna B., Ulus, Özden S., Van Goethem, Mireille, Veltman, Jeroen, Weigel, Stefanie, Wenkel, Evelyn, Zuiani, Chiara, Di Leo, Giovanni“…Patients in the MRI group were younger, had denser breasts, more cancers ≥ 20 mm, and a higher rate of invasive lobular histology than patients who underwent conventional imaging alone (p < 0.001 for all comparisons). …”
Publicado 2021
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149618“…Her bloods showed microcytic anaemia, raised ESR (peak 97mm/hr), CRP (peak 30mg/l), CK (peak 628 IU/l), and LDH (peak 512 IU/l), but normal ferritin and ACE. …”
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149619por Roldán, Rollin, Rodriguez, Shalim, Barriga, Fernando, Tucci, Mauro, Victor, Marcus, Alcala, Glasiele, Villamonte, Renán, Suárez-Sipmann, Fernando, Amato, Marcelo, Brochard, Laurent, Tusman, Gerardo“…RESULTS: Comparing supine baseline and final, respiratory compliance (29 ± 9 vs 32 ± 8 mL/cmH(2)O; p < 0.01) and PaO(2)/FIO(2) ratio (138 ± 36 vs 164 ± 46 mmHg; p < 0.01) increased, while driving pressure (13 ± 2 vs 11 ± 2 cmH(2)O; p < 0.01) and lung ultrasound consolidation score decreased [5 (4–5) vs 2 (1–4); p < 0.01]. …”
Publicado 2022
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149620por Wang, Weiwei, Zhang, Xindong, Zhu, Laimin, Chen, Yueqin, Dou, Weiqiang, Zhao, Fan, Zhou, Zhe, Sun, Zhanguo“…When D* ≥ 30.95 × 10(−3) mm(2)/s and MK ≥ 0.69, the NPI tended to be high grade (with areas under the curve (AUCs) of 0.712 and 0.647, respectively). …”
Publicado 2022
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