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149941“….: Etcetera, FADD: Fas-associated protein with death domain, FBS: Fetal bovine serum, FITC: Fluorescein isothiocyanate, G1: Gap 1, G2: Gap 2, HPLC: High-performance liquid chromatography, HRP: Horseradish peroxidase, IAPs: Inhibitor of apoptosis proteins, IC50: Inhibitory concentration at half maximal inhibitory, IKK-α: Inhibitor of nuclear factor kappa-B kinase subunit alpha, IKK-β: Inhibitor of nuclear factor kappa-B kinase subunit beta, IKK-γ: Inhibitor of nuclear factor kappa-B kinase subunit gamma, IKK: IκB kinase, IkBα: Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, m: Meter, M: Mitotic, mm: Millimeter, mRNA: Messenger ribonucleic acid, NaCl: Sodium chloride, NaVO4: Sodium orthovanadate, NEMO: NF-Kappa-B essential modulator, NF-κB: Nuclear factor kappa-light chain-enhancer of activated B cells, NSCLC: Nonsmall cell lung carcinoma, PBS: Phosphate buffered saline, PGE2: Prostaglandin E2, PI: Propidium iodide, PMSF: Phenylmethylsulfonyl fluoride, pRB: Phosphorylated retinoblastoma, R. angustifolia: Ruta angustifolia L. …”
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149942“…The concentration of (13)C(u)-glucose, (13)C(u)-fructose or (13)C(1)-pyruvate (1.8, 3.6, 7.2 or 14.4 mM) had no influence on the size of the observed lactate peak over a 4 h incubation. …”
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149943“…Temporal artery biopsy was negative, but took more than four weeks after starting steroids and was only 9mm in length. Serum screening was unremarkable for complements C3,4, antinuclear antibodies (ANA), anti neutrophil cytoplasmic antibodies (ANCA), bacterial or viral antibodies. …”
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149944por Munné, Santiago, Nakajima, Steven T, Najmabadi, Sam, Sauer, Mark V, Angle, Marlane J, Rivas, José L, Mendieta, Laura V, Macaso, Thelma M, Sawarkar, Sarthak, Nadal, Alexander, Choudhary, Kajal, Nezhat, Camran, Carson, Sandra A, Buster, John E“…The ovulation trigger was given when there were at least two dominant follicles ≥18 mm, followed by IUI of sperm. Uterine lavage occurred 4–6 days after the IUI. …”
Publicado 2020
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149945por Bosteels, Cedric, Maes, Bastiaan, Van Damme, Karel, De Leeuw, Elisabeth, Declercq, Jozefien, Delporte, Anja, Demeyere, Bénédicte, Vermeersch, Stéfanie, Vuylsteke, Marnik, Willaert, Joren, Bollé, Laura, Vanbiervliet, Yuri, Decuypere, Jana, Libeer, Frederick, Vandecasteele, Stefaan, Peene, Isabelle, Lambrecht, Bart“…PARTICIPANTS: Patients aged 18-80 years admitted to specialized COVID-19 wards in 5 Belgian hospitals with recent (< 2 weeks prior to randomization) confirmed COVID-19 infection and acute respiratory failure defined as a PaO2/FiO2 below 350 mmHg or SpO2 below 93% on minimal 2 L/min supplemental oxygen. …”
Publicado 2020
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149946por Cotter, Aoife, Wallace, Deborah, McCarthy, Cormac, Feeney, Eoin, O’Neill, Lorraine, Stack, John, McCarthy, Geraldine, Hussain, Rabia, Alvarez Barco, Elena, Doran, Peter, Mallon, Patrick“…Moderate to severe respiratory failure as defined by PaO(2)/FiO(2)≤300mmHg. INTERVENTION AND COMPARATOR: Intervention for participants in this trial is SOC plus Tocilizumab compared to SOC alone (comparator). …”
Publicado 2020
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149947“…CRP and ESR were 135 mg/L and 48mm/hr, respectively. Electrocardiogram showed new T-wave inversion in the anterolateral leads with significantly raised troponin levels. …”
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149948“…CASE REPORT - CASE DESCRIPTION: A 36-year old male patient born in Jamaica, presented in 2017 with unilateral left-sided testicular pain and enlargement measuring 20 x 16 x 18mm on ultrasound. This was initially suspected of malignancy or an atypical infection. …”
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149949“…The rest of her physical examination was normal. BP was 116/97 mmHg, heart rate 109 bpm and satO2 100%. Investigations demonstrated C-reactive protein 330mg/L, erythrocyte sedimentation rate 140, Ferritin 479, lymphopaenia 0.7x10(9), eGFR 54 with no haematoproteinuria, D-dimer 3.05 mg/L with INR 1.1, aPTT 1.3, fibrinogen 8.8 g/L. …”
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149950por Bach, Simon P, Gilbert, Alexandra, Brock, Kristian, Korsgen, Stephan, Geh, Ian, Hill, James, Gill, Talvinder, Hainsworth, Paul, Tutton, Matthew G, Khan, Jim, Robinson, Jonathan, Steward, Mark, Cunningham, Christopher, Levy, Bruce, Beveridge, Alan, Handley, Kelly, Kaur, Manjinder, Marchevsky, Natalie, Magill, Laura, Russell, Ann, Quirke, Philip, West, Nicholas P, Sebag-Montefiore, David“…Eligible participants were aged 18 years or older with rectal adenocarcinoma, staged T2 or lower, with a maximum diameter of 30 mm or less; patients with lymph node involvement or metastases were excluded. …”
Publicado 2020
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149951por Wahl, Richard L., Frey, Eric C., Jacene, Heather A., Kahl, Brad S., Piantadosi, Steven, Bianco, Jesus A., Hammes, Richard J., Jung, Miah, Kasecamp, Wayne, He, Bin, Sgouros, George, Flinn, Ian W., Swinnen, Lode J.“…Methods: 24 patients with CD20-positive relapsed or refractory rituximab-sensitive, low-grade, mantle cell, or diffuse large-cell NHL, with normal organ function, platelet counts > 75,000/mm(3), and <35% tumor involvement in the marrow were treated with Rituximab (375 mg/m(2)) weekly for 4 consecutive weeks, then one dose of cyclophosphamide 2.5 g/m(2) with filgrastim 10 mcg/kg/day until stem cell collection. …”
Publicado 2021
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149952por Schliemann, Benedikt, Raschke, Michael, Michel, Philipp, Heilmann, Lukas, Dyrna, Felix, Sußiek, Julia, Frank, Andre, Katthagen, Jan, Wermers, Jens“…Defects were created in 2 mm steps parallel to the long axis of the glenoid until dislocation occurred self-acting and a 3D measuring arm was used for morphometric measurements as depicted in Figure 1. …”
Publicado 2021
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149953por Cabirta, Alba, Izuzquiza, Macarena, Ruiz-Camps, Isabel, Valcarcel, David, Catala, Eva, Jimenez, M Moraima, Perez, Ana, Martin, Lucia, Rodriguez, Yva, Serna, Angel, Ruiz-Pace, Fiorella, Dienstmann, Rodrigo, Bobillo, Sabela, Carpio, Cecilia, Salamero, Olga, Abrisqueta, Pau, Bosch, Francesc“…Regarding laboratory parameters, stood out lymphopenia (65% of patients presented <1200 lymphocytes/mm3) and elevation of inflammation parameters, such as D-dimer (median 365 ng/mL, range 50-5860), ferritin (median 1063 ng/mL, range 73-14191), IL-6 (median 59,6 pg/mL, range 3-4079) and PCR (median 11,2 mg/dL, range 0,3-79,9). …”
Publicado 2020
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149954por Wilde, Lindsay, Binder, Adam F., Carabasi, Matthew, Filicko-O'Hara, Joanne, Wagner, John L., Alpdogan, Onder, Kasner, Margaret, Klumpp, Thomas R., Martinez-Outschoorn, Ubaldo, Palmisiano, Neil, Keiffer, Gina, Grosso, Dolores, Millenson, Michael, MacKenzie, Amy R., Zibelli, Allison, Flomenberg, Neal, Porcu, Pierluigi, Gergis, Usama“…In our small cohort, multiple myeloma was the most frequent HM diagnosis associated with COVID-19 infection, but this may be related to the prevalence of MM in our geographic area. The vast majority of HM patients with symptomatic COVID-19 were former smokers. …”
Publicado 2020
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149955por Pagnano, Katia B, Mourão Toreli, Ana Carolina, Perobelli, Leila Martins, Quixada, Acy TS, Seguro, Fernanda S, Bendit, Israel, Delamain, Marcia Torresan, Sapelli, Jaqueline, Moura, Muriel Silva, Bortolini, Jaisson, Lourenço, André LG, Gonçalves, Natália N, Conchon, Monika, Nucci, Fabio Moore, Oliveira, Luciene Da Cruz, Magalhães, Gustavo HR, Funke, Vaneuza, Tavares, Renato, Centrone, Renato Torrescasana, Santos, Fabio PS, Fogliatto, Laura, Palma, Leonardo Carvalho, Clementino, Nelma D, Hokama, Paula OM, Boquimpani, Carla M“…COVID-19 was classified as mild/moderate, severe (defined as tachypnoea [≥30 breaths per min], oxygen saturation ≤93% at rest, or PaO2/FiO2 ratio <300 mm Hg) and critical (respiratory failure requiring mechanical ventilation, septic shock, or other organ dysfunction or failure that requires intensive care). …”
Publicado 2020
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149956por Bikbov, Mukharram M., Kazakbaeva, Gyulli M., Rakhimova, Ellina M., Rusakova, Iuliia A., Fakhretdinova, Albina A., Tuliakova, Azaliia M., Panda-Jonas, Songhomitra, Gilmanshin, Timur R., Zainullin, Rinat M., Bolshakova, Natalia I., Safiullina, Kamilia R., Gizzatov, Ainur V., Ponomarev, Ildar P., Yakupova, Dilya F., Baymukhametov, Nail E., Nikitin, Nikolay A., Jonas, Jost B.Enlace del recurso
Publicado 2021
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149957“…Later review of these images suggested a stable 5mm haematoma that was present on the earlier scan, and enoxaparin was recommenced. …”
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149958por Alaya, R., Ben Ouhiba, A., Diarra, M., Zalc, J., Nang Nlome Nze, M., Hilliquin, P.“…La ponction avait révélé un liquide inflammatoire stérile. La VS était à 23 mm/1 h et la CRP à 9,7 mg/L. Le FR était positif à 56 U/L, les anti-CCP étaient négatifs, les FAN étaient à 1/320(e) et les anti-ECT étaient négatifs. …”
Publicado 2021
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149959por De Vries, Judith Juliana, Visser, Chantal, Geers, Lotte, Slotman, Johan A., Endeman, Henrik, Kruip, Marieke J.H.A., de Maat, Moniek P.M., Dutch COVID & Thrombosis Coalition, The“…Clots were formed by mixing citrated plasma with thrombin (final concentration 1 U/ml) and calcium (17 mM). We imaged the clots using stimulated emission depletion (STED) microscopy, a super-resolution technique in which a depletion laser is used to selectively switch off fluorophores surrounding the focal point, thereby increasing the resolution. …”
Publicado 2021
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149960por Gavrilina, Olga A., Zakurdaeva, Kristina A., Vasileva, Anastasia N., Dubov, Sergei, Dubov, Vitaly S., Vorobyev, Vladimir I., Butaev, Lev S., Gavrilova, Lubov, Toropova, Inessa Yu., Popova, Marina O., Siniaev, Aleksander A., Kaplanov, Kamil, Petrenko, Andrei, Ochirova, Oksana, Chelysheva, Ekaterina Yu., Sveshnikova, Yulia, Shuvaev, Vasily, Grishunina, Maria E., Chabaeva, Julia A., Karpova, Alina, Sukhareva, Alena, Baryshnikova, Dasha, Gaponova, Tatiana V., Troitskaya, Vera V., Savchenko, Valery G.“…Disease types (malignant/non-malignant [n (%)]): 618 (93%) / 48 (7%), including AML 115 (17%), MM 113 (17%), NHL 106 (16%), CML / CMPD 92 (14%), ALL 52 (8%), CLL 50 (8%), MDS 25 (4%), HCL 23 (3%), HL 21 (3%), AA 16 (2%), APL 11 (2%), others 42 (6%); among them induction phase / remission / relapse or refractory / NA in 237 (35%) / 231 (35%) / 152 (23%) / 46 (7%) pts. …”
Publicado 2021
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