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  1. 45981
    “…The molecular mechanisms of modern inhaled anesthetics are still poorly understood although they are widely used in clinical settings. …”
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    Sodium Channels as Targets for Volatile Anesthetics
  2. 45982
    “…It would be advantageous to have a method that is applicable directly to short sequences, of the kind extracted from samples in modern metagenomic research. This is achieved by the technique proposed here. …”
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    Peptide markers of aminoacyl tRNA synthetases facilitate taxa counting in metagenomic data
  3. 45983
    por Noakes, Timothy David
    Publicado 2012
    “…This article traces the evolution of our modern understanding of how the CNS regulates exercise specifically to insure that each exercise bout terminates whilst homeostasis is retained in all bodily systems. …”
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    Fatigue is a Brain-Derived Emotion that Regulates the Exercise Behavior to Ensure the Protection of Whole Body Homeostasis
  4. 45984
    “…One of the challenges of modern neuroscience is integrating voluminous data of diferent modalities derived from a variety of specimens. …”
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    Common Atlas Format and 3D Brain Atlas Reconstructor: Infrastructure for Constructing 3D Brain Atlases
  5. 45985
    por Ma, Wentao, Hu, Jiming
    Publicado 2012
    “…Third, the initial unstable membrane, composed of prebiotically available fatty acids, should have been superseded quite early by a more stable membrane (e.g., composed of phospholipids, like modern cells). Additionally, the membrane-takeover probably occurred at the transition of the two substages of the protocells. …”
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    Computer Simulation on the Cooperation of Functional Molecules during the Early Stages of Evolution
  6. 45986
    “…Phylogenetic analysis of all available VP1 sequences indicated the presence of two modern EV68 lineages. The 2010 UK strains belonged to lineage 2. …”
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    Lineages, Sub-Lineages and Variants of Enterovirus 68 in Recent Outbreaks
  7. 45987
    por Girard, Catherine, Renaud, Sabrina
    Publicado 2012
    “…Disparity changes of Palmatolepis thus reflect changes in the structure of the ecological space itself, which was prone to evolve during this ancient period where modern ecosystems were progressively shaped.…”
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    Disparity Changes in 370 Ma Devonian Fossils: The Signature of Ecological Dynamics?
  8. 45988
    “…Using computed tomography (CT) image data of the Gage skull in conjunction with modern anatomical MRI and diffusion imaging data obtained in contemporary right handed male subjects (aged 25–36), we computationally simulate the passage of the iron through the skull on the basis of reported and observed skull fiducial landmarks and assess the extent of cortical gray matter (GM) and WM damage. …”
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    Mapping Connectivity Damage in the Case of Phineas Gage
  9. 45989
    por Mneimneh, Saad
    Publicado 2012
    “…I will show that a simple and modern treatment of Mendel's laws using a Markov chain will make this step possible, and it will only require basic college-level probability and calculus. …”
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    Crossing Over…Markov Meets Mendel
  10. 45990
    “…These differences provide a strong link between the metagenome and the physiology of the mats, as well as new insights into the biological processes associated with carbonate precipitation in modern marine stromatolites.…”
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    Metagenomic and Metabolic Profiling of Nonlithifying and Lithifying Stromatolitic Mats of Highborne Cay, The Bahamas
  11. 45991
    “…ION also appears to be absent or unrecognizable is several taxa, including one of the basal avian groups, the tinamous, which suggests that the ION may have evolved only in the more modern group of birds, Neognathae. Finally, we demonstrate that evolutionary changes in the relative size and the cytoarchitectonic organization of ION have occurred largely independent of phylogeny. …”
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    Functional Implications of Species Differences in the Size and Morphology of the Isthmo Optic Nucleus (ION) in Birds
  12. 45992
    “…The ability to efficiently and accurately determine genotypes is a keystone technology in modern genetics, crucial to studies ranging from clinical diagnostics, to genotype-phenotype association, to reconstruction of ancestry and the detection of selection. …”
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    Double Digest RADseq: An Inexpensive Method for De Novo SNP Discovery and Genotyping in Model and Non-Model Species
  13. 45993
    “…BACKGROUND: Cyanobacteria are among the most abundant organisms on Earth and represent one of the oldest and most widespread clades known in modern phylogenetics. As the only known prokaryotes capable of oxygenic photosynthesis, cyanobacteria are considered to be a promising resource for renewable fuels and natural products. …”
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    The diversity of cyanobacterial metabolism: genome analysis of multiple phototrophic microorganisms
  14. 45994
    “…Working memory is integrally dependent upon prefrontal cortex and it has been suggested that voluntary control of working memory, enabling sustained emotion inhibition, was the crucial step in the evolution of modern humans. Consistent with this, recent fMRI studies suggest that working memory performance depends upon the capacity of prefrontal cortex to suppress bottom-up amygdala signals during emotional arousal. …”
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    Paradoxical Facilitation of Working Memory after Basolateral Amygdala Damage
  15. 45995
    “…Many palaeobiological analyses have concluded that modern birds (Neornithes) radiated no earlier than the Maastrichtian, whereas molecular clock studies have argued for a much earlier origination. …”
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    The Completeness of the Fossil Record of Mesozoic Birds: Implications for Early Avian Evolution
  16. 45996
    “…Empirical evaluation on benchmark datasets demonstrates that BEST outperforms several modern sequence-based B-cell epitope predictors including ABCPred, method by Chen et al. (2007), BCPred, COBEpro, BayesB, and CBTOPE, when considering the predictions from antigen chains and from the chain fragments. …”
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    BEST: Improved Prediction of B-Cell Epitopes from Antigen Sequences
  17. 45997
    “…The proportion of patients remaining in HIV care increased in more recent calendar years and among patients who initiated modern cART regimens. CONCLUSIONS/SIGNIFICANCE: Retention in HIV care is essential for optimizing individual and public health outcomes. …”
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    Attrition among Human Immunodeficiency Virus (HIV)- Infected Patients Initiating Antiretroviral Therapy in China, 2003–2010
  18. 45998
    “…They also show the value of modern MDCT diagnostics. Multi detector CT examinations allow for a proper evaluation of the vascular anomalies in mediastinum. …”
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    Aneurysm of the aberrant right subclavian artery – a case report
  19. 45999
    por López-Arbarello, Adriana
    Publicado 2012
    “…Therefore, the compilation of large data sets including the Mesozoic ginglymodians and the re-evaluation of several hypotheses of homology are essential to test the hypotheses of the Halecostomi vs. the Holostei, which is one of the major topics in the evolution of Mesozoic vertebrates and the origin of modern fish faunas.…”
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    Phylogenetic Interrelationships of Ginglymodian Fishes (Actinopterygii: Neopterygii)
  20. 46000
    “…Traditional medicines are used to reduce the severity, and rituals carried out to make it permanently inactive or to divert its recurrence. Although modern antimalaria may make the severity of subsequent pabboje episodes worse, nomads seek treatment in private health facilities against fevers that are persistent using antimalarial medicines. …”
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    Febrile illness experience among Nigerian nomads
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