“…Enzymes play a critical role in a wide array of industrial, medical, and research applications and with the recent explosion of genomic sequencing, we now have sequences for millions of enzymes for which there is no known structure. In order to utilize modern computational design tools for constructing inhibitors or engineering novel catalysts, the ability to accurately model enzymes is critical. …”
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“…CONCLUSION: To our knowledge, this report is the first study documenting the epidemiologic and clinical features of pediatric sarcomas in a modern Tanzanian pediatric hospital. Embryonal RMS and osteosarcomas should be prioritized for adapting treatment protocols from other countries.…”
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“…The concentration of wealth in the hands of a few at the expense of general impoverishment is a major problem in some modern societies. However, there is a general opposition to redistribution policies or to the application of a progressive taxation system. …”
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“…A survey conducted from 1993 to 2006 revealed that the percentage of tested samples with high levels of specific anti-TsM antibody declined from 8.3% to 2.2%, suggesting the continuing occurrence of NC in Korea. Modern imaging modalities have substantially improved the diagnostic accuracy of NC, and recent advances in the molecular biochemical characterization of the TsM cyst fluid proteome also significantly strengthened NC serodiagnosis. …”
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“…Modern agricultural practices have undeniably increased global food production. …”
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“…Furthermore, the single-frame motifs [Formula: see text] with a property of trinucleotide decoding and the framing motifs [Formula: see text] (also called circular code motifs; first introduced by Michel (2012)) with a property of reading frame decoding may have been involved in the early life genes to build the modern genetic code and the extant genes. They could have been involved in the stage without anticodon-amino acid interactions or in the Implicated Site Nucleotides (ISN) of RNA interacting with the amino acids. …”
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“…The unrivaled computing capabilities of modern GPUs meet the demand of processing massive amounts of data seen in many application domains. …”
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“…More recently, VANET communications research has strayed from the antiquated DSRC standard and favored more modern cellular technologies, such as fifth generation (5G). …”
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“…Our results are of further interest in the modern situation where increases in temperature are seeing the real possibility that tsetse will go extinct in some areas, without the need for intervention, but have an increased chance of surviving in other areas where they were previously unsustainable due to low temperatures.…”
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“…INTRODUCTION: In the modern day busy clinical practice, the communication between patient/relative and caregiver is at a minimal level. …”
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“…Terrestrial plants have contributed massively to the development of modern oncologic drugs. Despite the wide acceptance of Mauritian endemic flowering plants in traditional medicine, scientific evidence of their chemotherapeutic potential is lacking. …”
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“…Pain and loss of function are the main complaints reported by patients, inevitably leading towards a worsened daily life performance. New modern techniques have been developed with advanced cell based therapies. …”
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“…This finding supports the view that fast maturation rates in humans have coevolved with short lifespans and that such trade‐offs can be detected as intergenerational phenotypic correlations in modern populations. Menarcheal age of participants of Estonian Biobank (born between 1925 and 1996) did not predict the age of death of their mothers; however, it did predict survival of their fathers, but only in environment where the genetic variation is exposed (families where at least one parent had tertiary education). …”
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“…Modern cosmological simulations have reached the trillion-element scale, rendering data storage and subsequent analysis formidable tasks. …”
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“…BACKGROUND: In these modern times of digitization, the use of Internet has become an integral part of everyday life, especially the lives of adolescents. …”
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“…Agriculture is a primary driver of biodiversity loss worldwide, and several expensive schemes have been designed to make modern farming landscapes more hospitable for wildlife. …”
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“…Only mycotoxin enniatin B, at a level near the limit of detection, and low levels of isoflavones were detected in the feed, demonstrating the effectiveness of maximum level recommendations and modern feed processing technologies in the Norwegian aquaculture industry. …”
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“…Our own research suggests that previously used feed quality assessments should be verified by introducing modern methods of molecular biology and instrumental analysis. …”
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“…BACKGROUND: Temporomandibular joint dysfunction (TMD) therapy remains an open challenge for modern dentistry. Herein, we propose a new neuromuscular lingual device able to reduce signs and symptoms of TMD in female patients with chronic orofacial pain. …”
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“…Modern lifestyle limits our exposure to sunlight, which photosynthesizes vitamin D in the skin, and the incidence of nutritional rickets has been resurging. …”
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