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  1. 47441
    “…Despite recent developments within the sports chiropractic movement, the profession is still plagued by a minority of practitioners continuing to espouse certain marginal and outlandish technique systems that beleaguer the mainstream core of sports chiropractic as a cohesive and homogeneous group. Modern chiropractic management is frequently multimodal in nature and incorporates components of passive and active care. …”
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    Australian chiropractic sports medicine: half way there or living on a prayer?
  2. 47442
    “…BACKGROUND: Molecular interaction Information is a key resource in modern biomedical research. Publicly available data have previously been provided in a broad array of diverse formats, making access to this very difficult. …”
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    Broadening the horizon – level 2.5 of the HUPO-PSI format for molecular interactions
  3. 47443
    “…The discovery of transcriptional regulatory interactions has become a major topic in modern functional genomics. RESULTS: To facilitate the analysis of gene-regulatory networks, we have developed CoryneCenter, a web-based resource for the systematic integration and analysis of genome, transcriptome, and gene regulatory information for prokaryotes, especially corynebacteria. …”
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    CoryneCenter – An online resource for the integrated analysis of corynebacterial genome and transcriptome data
  4. 47444
    “…Most courses for health care professionals are delivered outside the work context ('stand alone') and lack adaptation to the specific needs for EBM at the learners' workplace. Courses with modern 'adaptive' EBM teaching that employ principles of effective continuing education might fill that gap. …”
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    A clinically integrated curriculum in Evidence-based Medicine for just-in-time learning through on-the-job training: The EU-EBM project
  5. 47445
    “…The relationships among clades and timing of the evolution of modern birds (Neoaves) has not yet been well resolved. …”
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    Bird evolution: testing the Metaves clade with six new mitochondrial genomes
  6. 47446
    “…Here, we present a method for inferring this distribution using Single Nucleotide Polymorphism (SNP) data from a population with non-stationary demographic history (such as that of modern humans). Application of our method to 47,576 coding SNPs found by direct resequencing of 11,404 protein coding-genes in 35 individuals (20 European Americans and 15 African Americans) allows us to assess the relative contribution of demographic and selective effects to patterning amino acid variation in the human genome. …”
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    Assessing the Evolutionary Impact of Amino Acid Mutations in the Human Genome
  7. 47447
    por Kovács, A F
    Publicado 2004
    “…Mainly, it was used in concurrent combination with radiation in organ-preserving settings. The modern method of transfemoral approach for catheterisation, superselective perfusion of the tumour-feeding vessel, and high-dose (150 mg m(−2)) administration of cisplatin with parallel systemic neutralisation with sodium thiosulphate (9 g m(−2)) made preoperative usage feasible. …”
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    Intra-arterial induction high-dose chemotherapy with cisplatin for oral and oropharyngeal cancer: long-term results
  8. 47448
    “…BACKGROUND: The development of modern producer strains with metabolically engineered pathways poses special problems that often require manipulating many genes and expressing them individually at different levels or under separate regulatory controls. …”
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    Dual-In/Out strategy for genes integration into bacterial chromosome: a novel approach to step-by-step construction of plasmid-less marker-less recombinant E. coli strains with predesigned genome structure
  9. 47449
    “…RESULTS: The EMMA 2 software has been designed to resolve shortcomings with respect to full MAGE-ML and ontology support and makes use of modern data integration techniques. We present a software system that features comprehensive data analysis functions for spotted arrays, and for the most common synthesized oligo arrays such as Agilent, Affymetrix and NimbleGen. …”
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    EMMA 2 – A MAGE-compliant system for the collaborative analysis and integration of microarray data
  10. 47450
    “…Our CRCT will also allow us to test interventions focussed on multidisciplinary ASU teams rather than individual disciplines, an imperative of modern hospital services. TRIAL REGISTRATION: Australia New Zealand Clinical Trial Registry (ANZCTR) No: ACTRN12608000563369…”
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    Fever, hyperglycaemia and swallowing dysfunction management in acute stroke: A cluster randomised controlled trial of knowledge transfer
  11. 47451
    “…However, few studies have examined muscle atrophy in humans using modern experimental techniques. The purpose of this study was to examine changes in global gene transcription during immobilization-induced muscle atrophy in humans and then explore the effects of the most prominent transcriptional alterations on protein expression and function. …”
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    Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women
  12. 47452
    “…Both these insertion dates predate the emergence of anatomically modern Homo sapiens.…”
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    Cross-Sectional Dating of Novel Haplotypes of HERV-K 113 and HERV-K 115 Indicate These Proviruses Originated in Africa before Homo sapiens
  13. 47453
    “…Motivation: Deregulated signaling cascades are known to play a crucial role in many pathogenic processes, among them are tumor initiation and progression. In the recent past, modern experimental techniques that allow for measuring the amount of mRNA transcripts of almost all known human genes in a tissue or even in a single cell have opened new avenues for studying the activity of the signaling cascades and for understanding the information flow in the networks. …”
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    A novel algorithm for detecting differentially regulated paths based on gene set enrichment analysis
  14. 47454
    “…INTRODUCTION: There is no current consensus on the most appropriate prosthesis for treating symptomatic osteoarthritis (OA) of the hip in young, active patients. Modern metal on metal hip resurfacing arthroplasty (HR) has gained popularity as it is theoretically more stable, bone conserving and easier to revise than total hip arthroplasty. …”
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    Metal on metal hip resurfacing versus uncemented custom total hip replacement - early results
  15. 47455
    “…Thus, we hypothesize that the species-specific release of evolutionary constraints for the mitochondrial genes of the proton-translocating ATPase is a consequence of altered heat homeostasis in modern humans.…”
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    Distinct patterns of mitochondrial genome diversity in bonobos (Pan paniscus) and humans
  16. 47456
    “…As work is a major component of Quality of Life (QOL), this finding has clinical, social, public health and economic implications in the modern era. Targeted depression interventions could facilitate RTW post-MI.…”
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    Depression as a predictor of work resumption following myocardial infarction (MI): a review of recent research evidence
  17. 47457
    “…This is achieved via parallelized analysis and modern distributed computing and, in one key setting, takes advantage of the properties of the updating algorithm for generalized linear models (GLMs). …”
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    DataSHIELD: resolving a conflict in contemporary bioscience—performing a pooled analysis of individual-level data without sharing the data
  18. 47458
    “…BACKGROUND: Transcriptome sequencing data has become an integral component of modern genetics, genomics and evolutionary biology. …”
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    De novo sequencing and characterization of floral transcriptome in two species of buckwheat (Fagopyrum)
  19. 47459
    “…To achieve deeper insights into the demographic history of modern humans in East Asia around the Last Glacial Maximum, we extensively analyzed mitochondrial DNA haplogroup M9a'b, a specific haplogroup that was suggested to have some potential for tracing the migration around the Last Glacial Maximum in East Eurasia. …”
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    Inland post-glacial dispersal in East Asia revealed by mitochondrial haplogroup M9a'b
  20. 47460
    “…BACKGROUND: Obesity and osteoporosis, two possibly related conditions, are rapidly expanding health concerns in modern society. Both of them are associated with sedentary life style and nutrition. …”
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    Effects of diet-induced obesity and voluntary wheel running on the microstructure of the murine distal femur
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