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47481por Woo, Jongchan, MacPherson, Cameron Ross, Liu, Jun, Wang, Huan, Kiba, Takatoshi, Hannah, Matthew A, Wang, Xiu-Jie, Bajic, Vladimir B, Chua, Nam-Hai“…BACKGROUND: Over application of phosphate fertilizers in modern agriculture contaminates waterways and disrupts natural ecosystems. …”
Publicado 2012
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47482por Belogurov, Alexey A., Stepanov, Alexey V., Smirnov, Ivan V., Melamed, Dobroslav, Bacon, Andrew, Mamedov, Azad E., Boitsov, Vitali M., Sashchenko, Lidia P., Ponomarenko, Natalia A., Sharanova, Svetlana N., Boyko, Alexey N., Dubina, Michael V., Friboulet, Alain, Genkin, Dmitry D., Gabibov, Alexander G.“…Despite the variety of therapeutics available against MS, the development of novel approaches to its treatment is of high importance in modern pharmaceutics. In this study, experimental autoimmune encephalomyelitis (EAE) in Dark Agouti rats has been treated with immunodominant peptides of the myelin basic protein (MBP) encapsulated in mannosylated small unilamellar vesicles. …”
Publicado 2013
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47483por Farías, María E., Rascovan, Nicolás, Toneatti, Diego M., Albarracín, Virginia H., Flores, María R., Poiré, Daniel G., Collavino, Mónica M., Aguilar, O. Mario, Vazquez, Martin P., Polerecky, Lubos“…In comparison to other modern stromatolites, they harbour an atypical microbial community characterized by highly abundant representatives of Deinococcus-Thermus, Rhodobacteraceae, Desulfobacterales and Spirochaetes. …”
Publicado 2013
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47484por Petersen, Jessica L., Mickelson, James R., Rendahl, Aaron K., Valberg, Stephanie J., Andersson, Lisa S., Axelsson, Jeanette, Bailey, Ernie, Bannasch, Danika, Binns, Matthew M., Borges, Alexandre S., Brama, Pieter, da Câmara Machado, Artur, Capomaccio, Stefano, Cappelli, Katia, Cothran, E. Gus, Distl, Ottmar, Fox-Clipsham, Laura, Graves, Kathryn T., Guérin, Gérard, Haase, Bianca, Hasegawa, Telhisa, Hemmann, Karin, Hill, Emmeline W., Leeb, Tosso, Lindgren, Gabriella, Lohi, Hannes, Lopes, Maria Susana, McGivney, Beatrice A., Mikko, Sofia, Orr, Nicholas, Penedo, M. Cecilia T., Piercy, Richard J., Raekallio, Marja, Rieder, Stefan, Røed, Knut H., Swinburne, June, Tozaki, Teruaki, Vaudin, Mark, Wade, Claire M., McCue, Molly E.“…This work provides further evidence of the importance of MSTN in racing breeds, provides strong evidence for selection upon gait and size, and illustrates the potential for population-based techniques to find genomic regions driving important phenotypes in the modern horse.…”
Publicado 2013
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47485por Aquilina, Alfred, Connelly, Douglas P., Copley, Jon T., Green, Darryl R. H., Hawkes, Jeffrey A., Hepburn, Laura E., Huvenne, Veerle A. I., Marsh, Leigh, Mills, Rachel A., Tyler, Paul A.“…Pore fluids extracted from Hook Ridge sediment were depleted in chloride, sulfate and magnesium by up to 8% relative to seawater, enriched in lithium, boron and calcium, and had a distinct strontium isotope composition ((87)Sr/(86)Sr = 0.708776 at core base) compared with modern seawater ((87)Sr/(86)Sr ≈0.70918), indicating advection of hydrothermal fluid through sediment at this site. …”
Publicado 2013
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47486“…Possible explanations are population growth, greater awareness of fractures, improved diagnostics, improved emergency care reducing fatalities, and a higher activity level of patients receiving modern medical therapy. Obviously the improvement of medical treatment did not reduce the susceptibility of these patients to unstable fractures. …”
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47487por Hiltunen, Pamela, Kuisma, Markku, Silfvast, Tom, Rutanen, Juha, Vaahersalo, Jukka, Kurola, Jouni“…BACKGROUND: Despite the efforts of the modern Emergency Medical Service Systems (EMS), survival rates for sudden out-of-hospital cardiac arrest (OHCA) have been poor as approximately 10% of OHCA patients survive hospital discharge. …”
Publicado 2012
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47488por Suvorova, Elena S., Croken, Matthew, Kratzer, Stella, Ting, Li-Min, de Felipe, Magnolia Conde, Balu, Bharath, Markillie, Meng L., Weiss, Louis M., Kim, Kami, White, Michael W.“…This study demonstrates investigations into diverse unicellular eukaryotes, like the Apicomplexa, have the potential to yield new insights into important mechanisms conserved across modern eukaryotic kingdoms.…”
Publicado 2013
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47489por Hu, Shao-ji, Ning, Tiao, Fu, Da-ying, Haack, Robert A., Zhang, Zhen, Chen, De-dao, Ma, Xue-yu, Ye, Hui“…Our results suggested that the modern logistical network (i.e., the transportation system) in China is a key medium by which humans have brought about population exchange of M. alternatus in mainland China, likely through inadvertent movement of infested wood packaging material associated with trade, and that this genetic exchange was primarily from the economically well-developed east coast of China, westward, to the less-developed interior. …”
Publicado 2013
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47490por Nguyen, Huong Thu, Eriksson, Bo, Tran, Toan Khanh, Nguyen, Chuc Thi Kim, Ascher, Henry“…CONCLUSION: During the twelve years studied, household income as well as the use of modern technology increased rapidly. In spite of that, the mean and variation of birth weight did not change systematically. …”
Publicado 2013
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47491por Oliver, Rebekah E., Tinker, Nicholas A., Lazo, Gerard R., Chao, Shiaoman, Jellen, Eric N., Carson, Martin L., Rines, Howard W., Obert, Donald E., Lutz, Joseph D., Shackelford, Irene, Korol, Abraham B., Wight, Charlene P., Gardner, Kyle M., Hattori, Jiro, Beattie, Aaron D., Bjørnstad, Åsmund, Bonman, J. Michael, Jannink, Jean-Luc, Sorrells, Mark E., Brown-Guedira, Gina L., Mitchell Fetch, Jennifer W., Harrison, Stephen A., Howarth, Catherine J., Ibrahim, Amir, Kolb, Frederic L., McMullen, Michael S., Murphy, J. Paul, Ohm, Herbert W., Rossnagel, Brian G., Yan, Weikai, Miclaus, Kelci J., Hiller, Jordan, Maughan, Peter J., Redman Hulse, Rachel R., Anderson, Joseph M., Islamovic, Emir, Jackson, Eric W.“…A physically anchored consensus map is foundational to modern genomics research; however, construction of such a map in oat (Avena sativa L., 2n = 6x = 42) has been hindered by the size and complexity of the genome, the scarcity of robust molecular markers, and the lack of aneuploid stocks. …”
Publicado 2013
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47492por Gokcumen, Omer, Zhu, Qihui, Mulder, Lubbertus C. F., Iskow, Rebecca C., Austermann, Christian, Scharer, Christopher D., Raj, Towfique, Boss, Jeremy M., Sunyaev, Shamil, Price, Alkes, Stranger, Barbara, Simon, Viviana, Lee, Charles“…Ancient population structure shaping contemporary genetic variation has been recently appreciated and has important implications regarding our understanding of the structure of modern human genomes. We identified a ∼36-kb DNA segment in the human genome that displays an ancient substructure. …”
Publicado 2013
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47493por Lucas, Mitchell R., Huynh, Bao-Lam, da Silva Vinholes, Patricia, Cisse, Ndiaga, Drabo, Issa, Ehlers, Jeffrey D., Roberts, Philip A., Close, Timothy J.“…In addition to delivering markers linked to major trait determinants in the context of modern breeding, we provide an analysis of the diversity of the USDA core collection of cowpea to identify genepools, migrants, admixture, and duplicates.…”
Publicado 2013
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47494por Välimäki, Maritta, Kurki, Marjo, Hätönen, Heli, Koivunen, Marita, Selander, Maarit, Saarijärvi, Simo, Anttila, Minna“…Despite policy guidance and governmental support to develop usable mental health services, there is still a lack of easily accessible and modern interventions available for adolescents in Finland’s majority official language. …”
Publicado 2012
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47495por Okogbenin, Emmanuel, Setter, Tim L., Ferguson, Morag, Mutegi, Rose, Ceballos, Hernan, Olasanmi, Bunmi, Fregene, Martin“…Cassava has a long growth cycle of 12–18 months which invariably contributes to a long breeding scheme for the crop. Modern breeding using advances in genomics and improved genotyping, is facilitating the dissection and genetic analysis of complex traits including drought tolerance, thus helping to better elucidate and understand the genetic basis of such traits. …”
Publicado 2013
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47496“…It is hypothesized that the iliac process or ridge present in most tetrapodomorph fish is the precursor to the tetrapod ilium and that its evolution mimicked its development in modern salamanders.…”
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47497por Rigaud, Charlotte, Lebre, Anne-Sophie, Touraine, Renaud, Beaupain, Blandine, Ottolenghi, Chris, Chabli, Allel, Ansquer, Helene, Ozsahin, Hulya, Di Filippo, Sylvie, De Lonlay, Pascale, Borm, Betina, Rivier, Francois, Vaillant, Marie-Catherine, Mathieu-Dramard, Michèle, Goldenberg, Alice, Viot, Géraldine, Charron, Philippe, Rio, Marlene, Bonnet, Damien, Donadieu, Jean“…CONCLUSIONS: This survey found that BTHS outcome was affected by cardiac events and by a risk of infection that was related to neutropenia. Modern management of heart failure and prevention of infection in infancy may improve the survival of patients with BTHS without the need for heart transplantation.…”
Publicado 2013
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47498“…To identify the evolutionary genetic novelties that contributed to shape human-specific traits such as the use of a complex language, long-term planning and exceptional learning abilities is one of the ultimate frontiers of modern biology. Evolutionary signatures of functional shifts could be detected by comparing noncoding regions that are highly conserved across mammals or primates and rapidly accumulated nucleotide substitutions only in the lineage leading to humans. …”
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47499por Alt, Kurt W., Benz, Marion, Müller, Wolfgang, Berner, Margit E., Schultz, Michael, Schmidt-Schultz, Tyede H., Knipper, Corina, Gebel, Hans-Georg K., Nissen, Hans J., Vach, Werner“…Genetic studies and a worldwide comparison of the general rate of this dental anomaly in modern and historic populations show that the enhanced frequency can only be explained by close familial relationships akin to endogamy. …”
Publicado 2013
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47500“…Although the multimodal stimulation provided by modern audiovisual video games is pleasing by itself, the rewarding nature of video game playing depends critically also on the players' active engagement in the gameplay. …”
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