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  1. 47621
    por Liu, Bo, Zhu, Dixian, Wang, Yadong
    Publicado 2016
    “…Moreover, the state-of-the-art approaches cannot well support scalable parallel computing owing to their incremental nature, which is a bottleneck to use modern computers to accelerate BWT construction. Results: We propose de Bruijn branch-based BWT constructor (deBWT), a novel parallel BWT construction approach. …”
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    deBWT: parallel construction of Burrows–Wheeler Transform for large collection of genomes with de Bruijn-branch encoding
  2. 47622
    “…Mounting an immune response sufficient to eradicate a tumor is the goal of modern immunotherapy. Single agent therapies with checkpoint inhibitors or costimulatory molecule agonists are effective only for a small portion of all treated patients. …”
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    How do I steer this thing? Using dendritic cell targeted vaccination to more effectively guide the antitumor immune response with combination immunotherapy
  3. 47623
    “…BACKGROUND: Catalytic RNAs, or ribozymes, are regarded as fossils of a prebiotic RNA world that have remained in the genomes of modern organisms. The simplest ribozymes are the small self-cleaving RNAs, like the hammerhead ribozyme, which have been historically considered biological oddities restricted to some RNA pathogens. …”
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    Retrozymes are a unique family of non-autonomous retrotransposons with hammerhead ribozymes that propagate in plants through circular RNAs
  4. 47624
    “…Majority (70%) sought treatment for illness in modern system of medicine and only few continued with the practice of herbs and traditional medicine. …”
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    Prevalence of malnutrition, diarrhea, and acute respiratory infections among under-five children of Sugali tribe of Chittoor district, Andhra Pradesh, India
  5. 47625
    “…Indeed, standing genetic variation within this wild Holarctic lineage of S. eubayanus is responsible for genetic variation still segregating among modern lager-brewing hybrids. We conclude that the relationships among wild strains of S. eubayanus and their domesticated hybrids reflect complex biogeographical and genetic processes.…”
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    Complex Ancestries of Lager-Brewing Hybrids Were Shaped by Standing Variation in the Wild Yeast Saccharomyces eubayanus
  6. 47626
    “…The procedure is done mainly by untrained service providers, with some providers using modern circumcision devices. There are no key messages on EIMC for families; the increasing demand for EIMC is led by the community. …”
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    Early Infant Male Circumcision in Cameroon and Senegal: Demand, Service Provision, and Cultural Context
  7. 47627
    “…BACKGROUND: Prolonged sitting is ubiquitous in modern society and linked to several diseases. Height-adjustable desks are being used to decrease worksite based sitting time (ST). …”
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    Effect of a novel two-desk sit-to-stand workplace (ACTIVE OFFICE) on sitting time, performance and physiological parameters: protocol for a randomized control trial
  8. 47628
    “…Objectives: Modern management of myeloma has significantly improved survival, with increasing numbers of patients living beyond a decade. …”
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    High prevalence of cardiovascular and respiratory abnormalities in advanced, intensively treated (transplanted) myeloma: The case for ‘late effects’ screening and preventive strategies
  9. 47629
    “…Additionally, ideas about indigenous contraceptives, notions of masculinity and femininity, misconceptions and fear of the side effects of contraceptives, make people of all ages wary of modern birth control. Other barriers include imposed contraceptive choice – meaning no choice, overly technical medical language used at clinics and the absence of healthcare workers more attuned to the needs of adolescents and young adults. …”
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    “It is challenging… oh, nobody likes it!”: a qualitative study exploring Mozambican adolescents and young adults’ experiences with contraception
  10. 47630
    “…A new graphical genome browser has been added, gene/genome visualization tools have been improved, and the graphical interface is now more modern, robust and user-friendly. PHASTER is available online at www.phaster.ca.…”
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    PHASTER: a better, faster version of the PHAST phage search tool
  11. 47631
    “…However, the awareness on the prevalence of mycotoxins, available modern techniques to analyze them, the effects of mycotoxicoses, and the recent developments in the ways to safely eliminate the mycotoxins from the feed are very minimal among the producers. …”
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    Prevalence and effects of mycotoxins on poultry health and performance, and recent development in mycotoxin counteracting strategies()
  12. 47632
    “…Government (27.6%) and private (21.1%) health facilities were the main sources of modern FP methods. Sixty two per cent of women reported current use of any FP method. …”
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    Knowledge, sources and use of family planning methods among women aged 15-49 years in Uganda: a cross-sectional study
  13. 47633
    “…Recent parsimony analyses of modern and fossil mammals imply up to seven independent postdentary trough losses or even reversals, which is unexpected given the complexity of these transformations. …”
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    Resolving the evolution of the mammalian middle ear using Bayesian inference
  14. 47634
    “…However, some of the best discriminative indices use parameters in the formulas that are only measured in modern counters and are not always available in small laboratories. …”
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    A new index to discriminate between iron deficiency anemia and thalassemia trait
  15. 47635
    “…First, the predicted proteome of Leishmania braziliensis was compared and analyzed by modern linear programs to find epitopes with the capacity to trigger an immune response. …”
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    Combination of In Silico Methods in the Search for Potential CD4(+) and CD8(+) T Cell Epitopes in the Proteome of Leishmania braziliensis
  16. 47636
    “…AIM: Asthma and obesity represent one of the most crucial public and health problems of modern society that frequently begin in childhood and have some mutual elements of risk. …”
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    The Effect of Body Mass Index on Spirometric Parameters in Children with Asthma
  17. 47637
    “…We found strong beliefs in traditional and spiritual healing in the population; use of both modern and traditional/spiritual treatments concurrently was common. …”
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    Predictors of diarrheal mortality and patterns of caregiver health seeking behavior in in Karachi, Pakistan
  18. 47638
    “…BACKGROUND: Natural products, including those derived from higher plants have, over the years, contributed greatly to the development of modern therapeutic drugs. Due to the medicinal importance in traditional practice and the diversified biology and chemistry of the constituents from Artemisia spp., the genus has been receiving growing attention. …”
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    Anti-inflammatory and acetylcholinesterase activity of extract, fractions and five compounds isolated from the leaves and twigs of Artemisia annua growing in Cameroon
  19. 47639
    “…BACKGROUND: Modern drug therapy accounts for a major share of health expenditure and challenges public provider resources. …”
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    Trends in annual drug expenditure – a 16 year perspective of a public healthcare maintenance organization
  20. 47640
    “…Archaeological sites in northern Africa provide a rich record of increasing importance for the origins of modern human behaviour and for understanding human dispersal out of Africa. …”
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    A New Chronology for Rhafas, Northeast Morocco, Spanning the North African Middle Stone Age through to the Neolithic
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