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  1. 47681
    “…Recently, we demonstrated that necrotic lung lesions could be induced in the C57BL/6 mice by highly virulent Mtb strains belonging to the modern Beijing sublineage. However, the pathogenic mechanisms leading to necrosis in this model were not elucidated. …”
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    Hypervirulent Mycobacterium tuberculosis strain triggers necrotic lung pathology associated with enhanced recruitment of neutrophils in resistant C57BL/6 mice
  2. 47682
    “…RESULTS: In this study, flow cells were attached to boreholes containing either “modern marine” or “old saline” waters of different origin and degree of isolation from the light-driven surface of the earth. …”
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    Potential for hydrogen-oxidizing chemolithoautotrophic and diazotrophic populations to initiate biofilm formation in oligotrophic, deep terrestrial subsurface waters
  3. 47683
    “…BACKGROUND: Modern civilization depends on only a few plant species for its nourishment. …”
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    Genomic history of the origin and domestication of common bean unveils its closest sister species
  4. 47684
    “…The trend in data collection is to compile more fine-grained data on lifestyle and severity of diseases, based on self-reporting and modern technologies. This will surely improve our ability to incorporate relevant confounders or their proxies. …”
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    Control of confounding in the analysis phase – an overview for clinicians
  5. 47685
    “…The trial will gain new knowledge of whether modern technology can augment the effects of traditional personalized safety planning. …”
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    MYPLAN –mobile phone application to manage crisis of persons at risk of suicide: study protocol for a randomized controlled trial
  6. 47686
    “…Compounds that recognize and strongly bind to molecular targets are one of the cornerstones of modern pharmaceutics. Work has been ongoing for the past 25 years on the therapeutic use of aptamers, nucleic acid molecules, whose three-dimensional structure is the result of interactions between complementary base pairs. …”
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    Anti-FGFR1 aptamer-tagged superparamagnetic conjugates for anticancer hyperthermia therapy
  7. 47687
    “…Soil acidification is a major problem in modern agricultural systems and is an important factor affecting the soil microbial community and soil health. …”
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    Soil Acidification Aggravates the Occurrence of Bacterial Wilt in South China
  8. 47688
    “…We believe our discoveries may conduce to isolating major genes and aid the improvement of flooding tolerance in modern breeding programs.…”
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    Association Mapping Reveals Novel Genetic Loci Contributing to Flooding Tolerance during Germination in Indica Rice
  9. 47689
    “…Increasing water use efficiency and reducing nitrogen pollutant discharge are important tasks for modern agriculture. To evaluate the effect of alternate partial root-zone irrigation (APRI) on tomato plant growth, water use efficiency and nitrate-(15)N uptake, an experiment was conducted from June to December in 2014 under greenhouse condition in northern China. …”
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    Growth, Water Use, and Nitrate-(15)N Uptake of Greenhouse Tomato as Influenced by Different Irrigation Patterns, (15)N Labeled Depths, and Transplant Times
  10. 47690
    “…Modelling GRNs from multiple experiments (also called integrative analysis) has; therefore, naturally become a standard procedure in modern computational biology. Indeed, such analysis is usually more robust than the traditional approaches, which suffer from experimental biases and the low number of samples by analysing individual datasets. …”
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    Study of Meta-analysis strategies for network inference using information-theoretic approaches
  11. 47691
    “…Estimating interactions between physiological systems is an important challenge in modern biomedical research. Here, we explore a new concept for quantifying information common in two time series by cross-compressibility. …”
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    Baroreflex Coupling Assessed by Cross-Compression Entropy
  12. 47692
    “…Biochar production and use are part of the modern agenda to recycle wastes, and to retain nutrients, pollutants, and heavy metals in the soil and to offset some greenhouse gas emissions. …”
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    Properties of biochar derived from wood and high-nutrient biomasses with the aim of agronomic and environmental benefits
  13. 47693
    “…Secured results are accessible and shareable on modern browsers. Vipie is a freely available web-based tool whose code is open source. …”
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    Vipie: web pipeline for parallel characterization of viral populations from multiple NGS samples
  14. 47694
    “…With modern intensive medical therapy, the annual risk of ipsilateral stroke in patients with asymptomatic carotid stenosis (ACS) is now down to ∼0.5%. …”
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    Appropriate management of asymptomatic carotid stenosis
  15. 47695
    “…CONTEXT: Type 2 diabetes is the modern epidemic wherein patient care needs multiple approaches, education, and self-awareness being one of them. …”
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    Knowledge, attitude, and practice of urban Gujarati type 2 diabetics: Prevalence and impact on disease control
  16. 47696
    “…Housing was visually assessed in a home visit and then classified as low, high, or medium quality, based on housing components being traditional, modern, or both, respectively. RESULTS: Overall, 11426 individuals were included in the study: 10960 uninfected and 466 infected (301 symptomatic and 165 asymptomatic). …”
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    Low-Quality Housing Is Associated With Increased Risk of Malaria Infection: A National Population-Based Study From the Low Transmission Setting of Swaziland
  17. 47697
    “…Investigator‐initiated trials (IIT) are important aspects of medical research and have contributed substantially to modern oncology. IIT using post‐approval drugs have been conducted by domestic institutions in Japan. …”
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    Quality evaluation of investigator‐initiated trials using post‐approval cancer drugs in Japan
  18. 47698
    “…BACKGROUND: Modern developmental biology relies heavily on the analysis of embryonic gene expression patterns. …”
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    Identifying spatially similar gene expression patterns in early stage fruit fly embryo images: binary feature versus invariant moment digital representations
  19. 47699
    “…CONCLUSIONS: Despite the fact that the results of gene expression analysis were highly consistent between Human Transcriptome Arrays and RNA-seq platforms, the analysis of alternative splicing produced discordant results. We concluded that modern microarrays can still outperform sequencing for standard analysis of gene expression in terms of reproducibility and cost. …”
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    RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples
  20. 47700
    “…Finally, we show that Parsis are genetically closer to Neolithic Iranians than to modern Iranians, who have witnessed a more recent wave of admixture from the Near East. …”
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    “Like sugar in milk”: reconstructing the genetic history of the Parsi population
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