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49121“…The use of modern neuroimaging methods to characterize the complex anatomy of brain development at different stages reveals an enormous wealth of information in understanding this highly ordered process and provides clues to detect neurological and neurobehavioral disorders that have their origin in early structural and functional cerebral maturation. …”
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49122por Mata, Helena, Gongora, Jaime, Eizirik, Eduardo, Alves, Brunna M, Soares, Marcelo A, Ravazzolo, Ana Paula“…Furthermore, we estimated that the majority of the Gamma-like integrations took place during the diversification of modern felids. Finally, our phylogenetic analyses indicate the presence of a genetically divergent group of sequences whose position in our phylogenetic tree was difficult to establish confidently relative to known retroviruses, and another lineage identified as ERVs belonging to class II. …”
Publicado 2015
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49123“…This is most likely explained by the strong bottleneck suggested to have occurred when modern humans migrated to East Asia. A higher frequency of variable sites was detected in the Africans. …”
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49124“…BACKGROUND: Over the last two decades, many approaches have been developed in bioinformatics that aim at one of the most promising, yet unsolved problems in modern life sciences - prediction of structural features of a protein. …”
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49125“…In a previous study we developed a finite-sites theory to characterize the uncertainty in Bayesian divergence time estimation in analysis of large but finite sequence data sets under a strict molecular clock. As most modern clock dating analyses use more than one locus and are conducted under relaxed clock models, here we extend the theory to the case of relaxed clock analysis of data from multiple loci (site partitions). …”
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49126“…This paper comprehensively reviews four important areas; (i) the significance of plant genetic diversity (PGD) and PGR especially on agriculturally important crops (mostly field crops); (ii) risk associated with narrowing the genetic base of current commercial cultivars and climate change; (iii) analysis of existing PGD analytical methods in pregenomic and genomic era; and (iv) modern tools available for PGD analysis in postgenomic era. …”
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49127“…BACKGROUND: Improvement in surgical devices and intraocular lenses has made modern cataract surgery a safe procedure with decreasing complication rates. …”
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49128por Tanimoto, Tetsuya“…To understand the challenges and opportunities in the Japanese pharmaceutical market, which occupies one tenth of the global share, this review highlights several issues related to the benefit-risk assessment that is unique to the modern Japanese society: 1) regulatory system for new drug development; 2) health hazards related to pharmaceuticals (“Yakugai” in Japanese); 3) drug lag; 4) problems and controversies in the vaccination policy; and 5) clinical study misconduct. …”
Publicado 2015
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49129“…To assess social inequalities in the use of antenatal care (ANC), facility based delivery (FBD), and modern contraception (MC) in two contrasting groups of countries in sub-Saharan Africa divided based on their progress towards maternal mortality reduction. …”
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49130“…CAM has persisted globally with over USD34 billion spent annually, despite modernization, globalization, technological advancement, and limited supportive evidence. …”
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49131“…Multidrug-resistant pathogens have become a serious problem in modern chemotherapy. Over the past decade, investigations into the structure of bacterial multidrug exporters have revealed the multidrug recognition and export mechanisms. …”
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49132“…INTRODUCTION: The intrauterine device (IUD) is one of the modern contraception methods that is reversible, safe, effective, and with long-term efficacy. …”
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49133“…The web-server is supported on all modern browsers with latest Java plug-in. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12859-015-0545-9) contains supplementary material, which is available to authorized users.…”
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49134“…It can also be suggested that, because of higher efficacy of assimilation from the diet, and possibilities of building Se reserves in the body, organic selenium in the form of selenomethionine (SeMet) provided by a range of products, including Se-Yeast and SeMet preparations is an important source of Se to better meet the needs of modern pig genotypes in commercial conditions of intensive pig production.…”
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49135por Rivollat, Maïté, Mendisco, Fanny, Pemonge, Marie-Hélène, Safi, Audrey, Saint-Marc, Didier, Brémond, Antoine, Couture-Veschambre, Christine, Rottier, Stéphane, Deguilloux, Marie-France“…Pairwise F (ST) values, haplogroup frequencies and shared informative haplotypes were calculated and compared with ancient and modern European and Near Eastern populations. These descriptive analyses provided patterns resulting from different evolutionary scenarios; however, the archaeological data available for the region suggest that the Gurgy group was formed through equivalent genetic contributions of farmer descendants from the Danubian and Mediterranean Neolithization waves. …”
Publicado 2015
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49136por Banu, Sayera, Rahman, Md. Toufiq, Uddin, Mohammad Khaja Mafij, Khatun, Razia, Khan, Md. Siddiqur Rahman, Rahman, Md. Mojibur, Uddin, Syed Iftekhar, Ahmed, Tahmeed, Heffelfinger, James D.“…Deletion analysis identified all isolates as M. tuberculosis and further identified 229 (70%) strains as ‘modern’ and 100 (30%) strains as ‘ancestral’. Analysis of MIRU showed that 347 strains (85%) exhibited unique patterns, whereas 61 strains (15%) clustered into 22 groups. …”
Publicado 2015
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49137“…CONCLUSION: Information technologies can help the development of the teaching process, and represent attractive and accessible tool in the process of modernization and progress.…”
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49138por Todorovska, Elena, Ivanova, Albena, Ganeva, Daniela, Pevicharova, Galina, Molle, Emil, Bojinov, Bojin, Radkova, Mariana, Danailov, Zhivko“…Genetic variability in modern crops is limited due to domestication and selection processes. …”
Publicado 2014
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49139por Maldonado, Manuel, Aguilar, Ricardo, Blanco, Jorge, García, Silvia, Serrano, Alberto, Punzón, Antonio“…In contrast, international plans for gas and oil extraction at those locations raise serious concerns over the need for protecting urgently this unique, vulnerable habitat to avoid further alteration. Modern lithistids are a relict fauna from Jurassic and Cretaceous reefs and the roots of the very genus Leiodermatium can be traced back to those fossil formations. …”
Publicado 2015
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49140por Tsai, Wen-Ting, Hassan, Ahmed, Sarkar, Purbasha, Correa, Joaquin, Metlagel, Zoltan, Jorgens, Danielle M., Auer, Manfred“…Modern 3D electron microscopy approaches have recently allowed unprecedented insight into the 3D ultrastructural organization of cells and tissues, enabling the visualization of large macromolecular machines, such as adhesion complexes, as well as higher-order structures, such as the cytoskeleton and cellular organelles in their respective cell and tissue context. …”
Publicado 2014
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