“…The study of genomic regions that contain gene copies and structural variation is a major challenge in modern genomics. Unlike variation involving single nucleotide changes, data on the variation of copy number is difficult to collect and few tools exist for analyzing the variation between individuals. …”
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“…This study therefore highlights the need to explore the impact of these perceptions on participants’ medication-taking behavior, and the need to address patients’ views of “modern” (commonly prescribed) and “traditional” (natural) medications through information and education, to ensure increased understanding of how medications are used for diabetes management.…”
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“…This specimen clearly represents a juvenile based on the extremely small size and open sutures/detached neural arches; total body length is estimated to be ∼1.1 m (modern adults of this species range from ∼4–6 m). …”
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“…Kidney stone formation during hyperoxaluric condition is inherently dependent on the interaction between renal epithelial cells and calcium oxalate (CaOx) crystals. Although modern medicine has progressed in terms of removal of these stones, recurrence and persistent side effects restricts their use. …”
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“…There is also a need for developing modern communication methods between the patient and the medical personnel. …”
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“…Research is needed to determine whether modern communications, particularly mobile health platforms (recently shown to improve medication adherence in other chronic diseases), can replicate or even enhance the successful elements of these interventions while using less time and fewer resources. …”
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“…BACKGROUND: Modern standards for evidence-based decision making in clinical care and public health still rely solely on eminence-based input when it comes to normative ethical considerations. …”
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“…Several possible reasons for these null findings have been proposed, including short treatment periods, relatively low doses of omega-3 PUFAs, small sample sizes, higher background omega-3 intakes, and the concurrent use of modern pharmacotherapy for CVD prevention. At least one of these caveats is being assessed in major clinical trials, with two omega-3 PUFA pharmacological agents being tested at doses of 4 g/day (instead of the more common <1 g/day). …”
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“…ABSTRACT: High-density linkage mapping in autopolyploid species has become possible in recent years given the increasing number of molecular markers now available through modern genotyping platforms. Such maps along with larger experimental populations are needed before we can obtain sufficient accuracy to make marker-trait association studies useful in practice. …”
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“…In fact, a lower‐than‐modern ocean phosphate inventory in our closed system model is unable to account for the Paleozoic prevalence of bottom‐water anoxia. …”
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“…Moreover, these tools are all open source, apply multiple levels of multithreading, and scale to the demands of modern next-generation sequencing data, which is essential for the analysis of massive multidisciplinary studies such as the Earth Microbiome Project (EMP) (J. …”
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“…Since several years, modern therapeutics targeting B cells and plasma cells have become available. …”
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“…Of these, 28.4% used modern contraception within 6 months of delivery. …”
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“…BACKGROUND: Melancholia is a kind of depression with the most common symptoms of evident mental disorder, slimness, lack of enjoyment, feeling guilty and having no appetite. In modern medicine, the word “melancholia” only refers to mental and affective symptoms of depression. …”
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“…It is recommended that we have a smarter approach to the traditional pharmacopoeias in order to use past experience and transcend existing knowledge of modern pharmacy.…”
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“…Generally, the wind speeds at all three locations seem quite low, average wind speeds of all the three studied locations fall below 4.0m/s which is far below the cut-in wind speed of many modern wind turbines. However we recommend the use of low cut-in speed wind turbines like the Savonius for stand alone low energy needs…”
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“…In this study, we evaluated the interactive effects of elevated [CO(2)] and moderate to severe water stress during the first part of the growth cycle on physiological traits and gene expression in four modern durum wheat genotypes. Physiological data showed that elevated [CO(2)] promoted plant growth but reduced N content. …”
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“…BACKGROUND: Total joint arthroplasties of the hip and knee represent a remarkable feat of modern medicine in terms of reducing pain and restoring function to millions of patients afflicted with severe arthritis. …”
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“…Multicenter, prospective, observational data are needed to validate the modern role of ERT in blunt trauma.…”
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“…These are major achievements in the perspective of Precision Medicine: a leading approach to the modern treatment strategy. Omalizumab, an anti-IgE antibody, has been the only biologic treatment available on the market for severe asthma during the last decade. …”
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