“…We found a significant improvement in overall survival in the modern (post-2015) era, associated with stereotactic radiotherapy and especially ICIs. …”
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“…The prognosis has remained poor despite recent advances in systemic and modern X-ray radiotherapy. Boron neutron capture therapy (BNCT) represents an alternative radiotherapy technique for GBM. …”
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“…A new piece of information in this field was the fact that psoriasis and autoimmune thyroid diseases (ATD) have been shown to be related to the immune-based side effects of modern anticancer drugs—namely, immune checkpoint inhibitors (ICP). …”
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“…Many of these stray animals are euthanized, negatively impacting the mental health of staff involved, and increasing the risk of depression, traumatic stress, substance abuse and suicide. Modern sheltering practices aim to reduce the number of stray cats and dogs, which reduces shelter admissions and euthanasia. …”
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“…INTRODUCTION: From 2018 to 2020, Adolescents 360 (A360), aiming to increase demand for and voluntary uptake of modern contraception among adolescent girls 15–19 years, designed and scaled an intervention in Tanzania (Kuwa Mjanja) to 13 regions through project-funded expansion. …”
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“…Thus, screening, monitoring and prevention of conditions inducing muscle wasting and weakness are essential to improve life quality in the ageing modern society. To this aim, the reliability of easily accessible and non‐invasive blood‐derived biomarkers is being evaluated. …”
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“…INTRODUCTION: Rejection remains the main cause of allograft failure in paediatric kidney transplantation and is driven by donor-recipient HLA mismatching. Modern computational algorithms enable assessment of HLA mismatch immunogenicity at the molecular level (molecular-mismatch, molMM). …”
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“…Automated external defibrillators began appearing in the late 1980s allowing the therapy to be delivered by EMTs and lay people. The ‘father’ of the modern automated external defibrillator (AED), Professor James Francis (1916-2004) was a physician and cardiologist from Northern Ireland who transformed emergency medicine and paramedic services with the invention of the portable defibrillator. …”
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“…Sleep disturbances occur in up to 70% of patients with mild traumatic brain injury (mTBI). Modern mTBI management recommends targeted treatment for the patient's unique clinical manifestations (i.e., obstructive sleep apnea, insomnia). …”
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“…SIMPLE SUMMARY: Modern pig production seeks to achieve favorable growth results while paying close attention to animal welfare and the quality of the pork, as well as maximizing the use of feed grown on the farm. …”
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“…As ruminants are globally distributed, the study of horn formation is critical not only for increasing our understanding of natural and sexual selection but also for the breeding of polled sheep breeds to facilitate modern sheep farming. Despite this, a significant number of the underlying genetic pathways in sheep horn remain unclear. …”
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“…First, we aimed to evaluate the phytotherapeutic potential of Sempervivum tectorum L., a traditionally well-known but chemically less characterized medicinal plant, through quantitative analysis of its biologically active substances. Modern methods of phytoanalytics (microwave extraction, lyophilization, and UV spectrophotometry) were applied to investigate the polyphenol and proanthocyanidin contents of Sempervivum tectorum L., which have significant biological and pharmacological activities, including antimicrobial activity. …”
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“…Wumei Bolus is a traditional Chinese medicine prescription, first appeared in Shennong Bencao Jing. Modern pharmacology believes that Wumei Bolus has antibacterial, antitussive, sedative, antiviral and anti-tumor effects, and plays a therapeutic role by acting on multi-target/multi-pathway. …”
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“…The practical application of modeling results to predict the development of the modern pandemic in 2020 has shown the fundamental limitations of the basic methods of model building. …”
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“…Targeting four main mineral elements and eight trace mineral elements contained in the fruit, the differences in mineral content in the peel and pulp of different varieties of P. ussuriensis were analyzed, compared and classified using modern microwave digestion ICP-MS. RESULTS: The mineral elements in the fruit of P. ussuriensis generally followed the following content pattern: K > P > Ca > Mg > Na > Al > Fe > Zn > Cu > Cr > Pb > Cd. …”
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“…Today, in the modern world, people are often exposed to electromagnetic waves, which can have undesirable effects on cell components that lead to differentiation and abnormalities in cell proliferation, deoxyribonucleic acid (DNA) damage, chromosomal abnormalities, cancers, and birth defects. …”
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“…RESULTS: The dietary habits of the cohort showed that participant diets contained a high ratio (9.3 ± 0.2, mean ± SEM) of linoleic acid (n−6) to alpha-linolenic acid (n−3) and also contained extremely low levels of n−3 HUFAs (eicosapentaenoic acid, EPA and docosahexaenoic acid, DHA), both features of the Modern Western Diet. Compared to African and European American cohorts, the frequency of the TT rs174537 genotype was highly enriched (53% of subjects) in this Hispanic/Latino cohort and was strongly associated with lower circulating HUFA levels. …”
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“…Background Today's world of cut-throat competition is boggling with stress as the most common problem among the modern generation, and reduction in stress demands a radical solution. …”
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“…These real-world data provide evidence for a role of body composition and immuno-nutritional status in the context of CD19.CAR-T and suggest that the obesity paradox may extend to modern T cell–based immunotherapies. See related Spotlight by Nawas and Scordo, p. 704…”
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“…Thus, ODH complementarily combined with A&EI is meant to enhance policies and systems and modernize emergency management.…”
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