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  1. 54961
    “…Based on the theory of Chinese medicine and the modern pharmacological knowledge of herbal medicines, we have designed a neuroprotective formula called Post-Stroke Rehabilitation (PSR), comprising seven herbs – Astragalus membranaceus (Fisch.) …”
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    Neuroprotective effect of a novel Chinese herbal decoction on cultured neurons and cerebral ischemic rats
  2. 54962
    “…BACKGROUND: Functionalized nanoparticles (NPs) are one promising tool for detecting specific molecular targets and combine molecular biology and nanotechnology aiming at modern imaging. We aimed at ligand-directed delivery with a suitable target-biomarker to detect early pancreatic ductal adenocarcinoma (PDAC). …”
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    Synthesis and functionalization of protease-activated nanoparticles with tissue plasminogen activator peptides as targeting moiety and diagnostic tool for pancreatic cancer
  3. 54963
    “…RESULTS: Current use of any modern contraception ranged from 86.2% in Tete to 98.4% in Mombasa (p = 0.001), while non-barrier contraception (hormonal, IUD or sterilisation) varied from 33.4% in Durban to 85.1% in Mysore (p < 0.001). …”
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    Sexual and reproductive health services utilization by female sex workers is context-specific: results from a cross-sectional survey in India, Kenya, Mozambique and South Africa
  4. 54964
    “…One of the biggest projects of the modern science—1000 Genomes—involves identification of single nucleotide polymorphisms (SNPs), i.e., differences of individual genomes from the reference genome. …”
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    Candidate SNP markers of aggressiveness-related complications and comorbidities of genetic diseases are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters
  5. 54965
    por Asfaw, Yonas, Boateng, Isaac, Calderon, Mauricio, Caleo, Grazia, Conteh, Allan, Conteh, Salifu, Dafae, Foday, Dey, Achintya, Duffy, Nadia, Davies, Daffney, Fatoma, Patrick, Fleming, John, Gogra, Boima, Gorina, Yelena, Grigoryan, Anna, Hersey, Sara, Hoare, Sam, Jabbi, Sonnia-Magba Bu-Buakei, Jambai, Amara, Jasperse, Joseph, Kaiser, Reinhard, Kallon, Gandi, Kamara, Ansumana, Kamara, Fatmata Zara, Kamara, Isata Pamela, Kamara, Wogba, Kandeh, Joseph, Kanu, Mustapha, Kargbo, Mabinty, Kargbo, Samuel, Konie, Richard, Kuyembeh, Simeon, Lansana, Patrick, Mclysaght, Fiona, McCann, Sheena, Nallo, Alhaji Samuka, Ngai, Stephanie, Nichols, Erin, Njuguna, Charles, O-Tipo, Shikanga, Parker, Sulaiman, Rafique, Nuzhat, Redd, John, Samba, Thomas, Souza, Kerry, Tran, Alex, Younge, Chief Mathew Gibao
    Publicado 2017
    “…Despite the many challenges identified, all participants stressed the need for modernizing and improving death registration in Sierra Leone. …”
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    Interagency technical consultation on improving mortality reporting in Sierra Leone: meeting report
  6. 54966
    “…Significant numbers of patients still suffer from significant acute pain, despite the advent of modern multimodal analgesic strategies. Mismanaged acute pain has a broad societal impact as significant numbers of patients may progress to suffer from chronic pain. …”
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    The ACTTION–APS–AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions
  7. 54967
    “…BACKGROUND: Single nucleotide polymorphism (SNP) arrays for domestic cattle have catalyzed the identification of genetic markers associated with complex traits for inclusion in modern breeding and selection programs. Using actual and imputed Illumina 778K genotypes for 3887 U.S. beef cattle from 3 populations (Angus, Hereford, SimAngus), we performed genome-wide association analyses for feed efficiency and growth traits including average daily gain (ADG), dry matter intake (DMI), mid-test metabolic weight (MMWT), and residual feed intake (RFI), with marker-based heritability estimates produced for all traits and populations. …”
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    Genome-wide association study for feed efficiency and growth traits in U.S. beef cattle
  8. 54968
    “…Without an alternate method available, modern hip JRF biomechanical studies involve this stripping of periarticular tissues, potentially sacrificing accurate measurements. …”
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    Radiographic Validation of a Non-invasive Method of Measuring Hip Joint Reaction Force using a Cartilage Relaxation Technique
  9. 54969
    “…CONCLUSIONS: The overall long-term symptom burden seen in this older OPC cohort treated with modern standard therapy was largely favorable, yet a higher symptom group (~35%) with a distinct pattern of mostly local and classically RT-related symptoms was identified. …”
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    Long-term patient reported outcomes following radiation therapy for oropharyngeal cancer: cross-sectional assessment of a prospective symptom survey in patients ≥65 years old
  10. 54970
    “…Human-mediated introgression, which is due, in particular, to importing Chinese pigs into the UK during the eighteenth and nineteenth centuries, played an important role in the formation of modern pig breeds. Inbreeding levels vary markedly between populations, from almost no runs of homozygosity (ROH) in a number of Asian wild boar populations, to up to 20% of the genome covered by ROH in a number of Southern European breeds. …”
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    Genome-wide SNP data unveils the globalization of domesticated pigs
  11. 54971
    “…BACKGROUND: The progress of medicine, science, technology, education, and culture improves, year by year, quality of life and life expectancy of the populace. The modern human has a chance to further improve the quality and duration of his/her life and the lives of his/her loved ones by bringing their lifestyle in line with their sequenced individual genomes. …”
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    Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters
  12. 54972
    “…However, this research is limited by several factors: the cost of equipment installation; management and storage of the large amounts of data collected; and data reduction, coding, and analyses. Modern smartphone technology includes accelerometers built into phones, and the vast, global proliferation of smartphones could provide a possible low-cost alternative for assessing kinematic risky driving. …”
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    Measuring Risky Driving Behavior Using an mHealth Smartphone App: Development and Evaluation of gForce
  13. 54973
    “…The vine is highly invasive in its introduced areas, including the southeastern US. Modern molecular marker resources are limited for the species, despite its importance. …”
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    De novo transcriptome assembly of Pueraria montana var. lobata and Neustanthus phaseoloides for the development of eSSR and SNP markers: narrowing the US origin(s) of the invasive kudzu
  14. 54974
    “…The western part of the country (the Niayes area) concentrates modern farms with exotic horses of high value and was highly affected during the 2007 outbreak that has started in the area. …”
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    Spatial distribution modelling of Culicoides (Diptera: Ceratopogonidae) biting midges, potential vectors of African horse sickness and bluetongue viruses in Senegal
  15. 54975
    “…BACKGROUND: The burden of preterm birth, fetal growth impairment, and associated neonatal deaths disproportionately falls on low- and middle-income countries where modern obstetric tools are not available to date pregnancies and monitor fetal growth accurately. …”
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    INTERGROWTH-21st Gestational Dating and Fetal and Newborn Growth Standards in Peri-Urban Nairobi, Kenya: Quasi-Experimental Implementation Study Protocol
  16. 54976
    “…CONCLUSIONS: Our results identified a set of significant QTLs for rubber tree, showing that the performance of modern Asiatic cultivars can still be improved and paving the way for further marker-assisted selection, which could accelerate breeding programs. …”
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    QTL detection for growth and latex production in a full-sib rubber tree population cultivated under suboptimal climate conditions
  17. 54977
    “…CONCLUSION: The H3ABioNet workflows have been implemented in view of offering ease of use for the end user and high levels of reproducibility and portability, all while following modern state of the art bioinformatics data processing protocols. …”
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    Developing reproducible bioinformatics analysis workflows for heterogeneous computing environments to support African genomics
  18. 54978
    “…BACKGROUND: Demands on health services across are increasing because of the combined challenges of an expanding and aging population, alongside complex comorbidities that transcend the classical boundaries of modern health care. Continuing to provide and coordinate care in the current manner is not a viable route to sustain the improvements in health outcomes observed in recent history. …”
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    The Internet of Things in Health Care in Oxford: Protocol for Proof-of-Concept Projects
  19. 54979
    “…Uniform criteria for GDM diagnosis, supported by robust evidence for the benefits of treatment, are urgently needed to guide modern GDM screening and treatment strategies.…”
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    Epidemiology of gestational diabetes mellitus according to IADPSG/WHO 2013 criteria among obese pregnant women in Europe
  20. 54980
    “…Thus, plants natural products have become an excellent option for modern therapeutics. Malva parviflora is a plant well known for its anti-inflammatory properties. …”
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    Malva parviflora extract ameliorates the deleterious effects of a high fat diet on the cognitive deficit in a mouse model of Alzheimer’s disease by restoring microglial function via a PPAR-γ-dependent mechanism
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