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54961por Ip, Fanny Chui-Fun, Zhao, Yu-Ming, Chan, Kim-Wan, Cheng, Elaine Yee-Ling, Tong, Estella Pui-Sze, Chandrashekar, Oormila, Fu, Guang-Miao, Zhao, Zhong-Zhen, Ip, Nancy Yuk-Yu“…Based on the theory of Chinese medicine and the modern pharmacological knowledge of herbal medicines, we have designed a neuroprotective formula called Post-Stroke Rehabilitation (PSR), comprising seven herbs – Astragalus membranaceus (Fisch.) …”
Publicado 2016
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54962por Dobiasch, Sophie, Szanyi, Szilard, Kjaev, Aleko, Werner, Jens, Strauss, Albert, Weis, Christian, Grenacher, Lars, Kapilov-Buchman, Katya, Israel, Liron-Limor, Lellouche, Jean-Paul, Locatelli, Erica, Franchini, Mauro Comes, Vandooren, Jennifer, Opdenakker, Ghislain, Felix, Klaus“…BACKGROUND: Functionalized nanoparticles (NPs) are one promising tool for detecting specific molecular targets and combine molecular biology and nanotechnology aiming at modern imaging. We aimed at ligand-directed delivery with a suitable target-biomarker to detect early pancreatic ductal adenocarcinoma (PDAC). …”
Publicado 2016
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54963por Lafort, Yves, Greener, Ross, Roy, Anuradha, Greener, Letitia, Ombidi, Wilkister, Lessitala, Faustino, Skordis-Worrall, Jolene, Beksinska, Mags, Gichangi, Peter, Reza-Paul, Sushena, Smit, Jenni A., Chersich, Matthew, Delva, Wim“…RESULTS: Current use of any modern contraception ranged from 86.2% in Tete to 98.4% in Mombasa (p = 0.001), while non-barrier contraception (hormonal, IUD or sterilisation) varied from 33.4% in Durban to 85.1% in Mysore (p < 0.001). …”
Publicado 2017
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54964por Chadaeva, Irina V., Ponomarenko, Mikhail P., Rasskazov, Dmitry A., Sharypova, Ekaterina B., Kashina, Elena V., Matveeva, Marina Yu, Arshinova, Tatjana V., Ponomarenko, Petr M., Arkova, Olga V., Bondar, Natalia P., Savinkova, Ludmila K., Kolchanov, Nikolay A.“…One of the biggest projects of the modern science—1000 Genomes—involves identification of single nucleotide polymorphisms (SNPs), i.e., differences of individual genomes from the reference genome. …”
Publicado 2016
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54965por Asfaw, Yonas, Boateng, Isaac, Calderon, Mauricio, Caleo, Grazia, Conteh, Allan, Conteh, Salifu, Dafae, Foday, Dey, Achintya, Duffy, Nadia, Davies, Daffney, Fatoma, Patrick, Fleming, John, Gogra, Boima, Gorina, Yelena, Grigoryan, Anna, Hersey, Sara, Hoare, Sam, Jabbi, Sonnia-Magba Bu-Buakei, Jambai, Amara, Jasperse, Joseph, Kaiser, Reinhard, Kallon, Gandi, Kamara, Ansumana, Kamara, Fatmata Zara, Kamara, Isata Pamela, Kamara, Wogba, Kandeh, Joseph, Kanu, Mustapha, Kargbo, Mabinty, Kargbo, Samuel, Konie, Richard, Kuyembeh, Simeon, Lansana, Patrick, Mclysaght, Fiona, McCann, Sheena, Nallo, Alhaji Samuka, Ngai, Stephanie, Nichols, Erin, Njuguna, Charles, O-Tipo, Shikanga, Parker, Sulaiman, Rafique, Nuzhat, Redd, John, Samba, Thomas, Souza, Kerry, Tran, Alex, Younge, Chief Mathew Gibao“…Despite the many challenges identified, all participants stressed the need for modernizing and improving death registration in Sierra Leone. …”
Publicado 2017
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54966por Kent, Michael L., Tighe, Patrick J., Belfer, Inna, Brennan, Timothy J., Bruehl, Stephen, Brummett, Chad M., Buckenmaier, Chester C., Buvanendran, Asokumar, Cohen, Robert I., Desjardins, Paul, Edwards, David, Fillingim, Roger, Gewandter, Jennifer, Gordon, Debra B., Hurley, Robert W., Kehlet, Henrik, Loeser, John D., Mackey, Sean, McLean, Samuel A., Polomano, Rosemary, Rahman, Siamak, Raja, Srinivasa, Rowbotham, Michael, Suresh, Santhanam, Schachtel, Bernard, Schreiber, Kristin, Schumacher, Mark, Stacey, Brett, Stanos, Steven, Todd, Knox, Turk, Dennis C., Weisman, Steven J., Wu, Christopher, Carr, Daniel B., Dworkin, Robert H., Terman, Gregory“…Significant numbers of patients still suffer from significant acute pain, despite the advent of modern multimodal analgesic strategies. Mismanaged acute pain has a broad societal impact as significant numbers of patients may progress to suffer from chronic pain. …”
Publicado 2017
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54967por Seabury, Christopher M., Oldeschulte, David L., Saatchi, Mahdi, Beever, Jonathan E., Decker, Jared E., Halley, Yvette A., Bhattarai, Eric K., Molaei, Maral, Freetly, Harvey C., Hansen, Stephanie L., Yampara-Iquise, Helen, Johnson, Kristen A., Kerley, Monty S., Kim, JaeWoo, Loy, Daniel D., Marques, Elisa, Neibergs, Holly L., Schnabel, Robert D., Shike, Daniel W., Spangler, Matthew L., Weaber, Robert L., Garrick, Dorian J., Taylor, Jeremy F.“…BACKGROUND: Single nucleotide polymorphism (SNP) arrays for domestic cattle have catalyzed the identification of genetic markers associated with complex traits for inclusion in modern breeding and selection programs. Using actual and imputed Illumina 778K genotypes for 3887 U.S. beef cattle from 3 populations (Angus, Hereford, SimAngus), we performed genome-wide association analyses for feed efficiency and growth traits including average daily gain (ADG), dry matter intake (DMI), mid-test metabolic weight (MMWT), and residual feed intake (RFI), with marker-based heritability estimates produced for all traits and populations. …”
Publicado 2017
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54968por Schaffer, Joseph Christopher, Vasconcellos, Daniel, Kaplan, Nathan, Maqsoodi, Noorullah, Olles, Mark, Elfar, John C., Giordano, Brian D.“…Without an alternate method available, modern hip JRF biomechanical studies involve this stripping of periarticular tissues, potentially sacrificing accurate measurements. …”
Publicado 2017
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54969por Eraj, Salman A., Jomaa, Mona K., Rock, Crosby D., Mohamed, Abdallah S. R., Smith, Blaine D., Smith, Joshua B., Browne, Theodora, Cooksey, Luke C., Williams, Bowman, Temple, Brandi, Preston, Kathryn E., Aymar, Jeremy M., Gross, Neil D., Weber, Randal S., Hessel, Amy C., Ferrarotto, Renata, Phan, Jack, Sturgis, Erich M., Hanna, Ehab Y., Frank, Steven J., Morrison, William H., Goepfert, Ryan P., Lai, Stephen Y., Rosenthal, David I., Mendoza, Tito R., Cleeland, Charles S., Hutcheson, Kate A., Fuller, Clifton D., Garden, Adam S., Gunn, G. Brandon“…CONCLUSIONS: The overall long-term symptom burden seen in this older OPC cohort treated with modern standard therapy was largely favorable, yet a higher symptom group (~35%) with a distinct pattern of mostly local and classically RT-related symptoms was identified. …”
Publicado 2017
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54970por Yang, Bin, Cui, Leilei, Perez-Enciso, Miguel, Traspov, Aleksei, Crooijmans, Richard P. M. A., Zinovieva, Natalia, Schook, Lawrence B., Archibald, Alan, Gatphayak, Kesinee, Knorr, Christophe, Triantafyllidis, Alex, Alexandri, Panoraia, Semiadi, Gono, Hanotte, Olivier, Dias, Deodália, Dovč, Peter, Uimari, Pekka, Iacolina, Laura, Scandura, Massimo, Groenen, Martien A. M., Huang, Lusheng, Megens, Hendrik-Jan“…Human-mediated introgression, which is due, in particular, to importing Chinese pigs into the UK during the eighteenth and nineteenth centuries, played an important role in the formation of modern pig breeds. Inbreeding levels vary markedly between populations, from almost no runs of homozygosity (ROH) in a number of Asian wild boar populations, to up to 20% of the genome covered by ROH in a number of Southern European breeds. …”
Publicado 2017
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54971por Chadaeva, Irina V., Ponomarenko, Petr M., Rasskazov, Dmitry A., Sharypova, Ekaterina B., Kashina, Elena V., Zhechev, Dmitry A., Drachkova, Irina A., Arkova, Olga V., Savinkova, Ludmila K., Ponomarenko, Mikhail P., Kolchanov, Nikolay A., Osadchuk, Ludmila V., Osadchuk, Alexandr V.“…BACKGROUND: The progress of medicine, science, technology, education, and culture improves, year by year, quality of life and life expectancy of the populace. The modern human has a chance to further improve the quality and duration of his/her life and the lives of his/her loved ones by bringing their lifestyle in line with their sequenced individual genomes. …”
Publicado 2018
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54972por Freidlin, Raisa Z, Dave, Amisha D, Espey, Benjamin G, Stanley, Sean T, Garmendia, Marcial A, Pursley, Randall, Ehsani, Johnathon P, Simons-Morton, Bruce G, Pohida, Thomas J“…However, this research is limited by several factors: the cost of equipment installation; management and storage of the large amounts of data collected; and data reduction, coding, and analyses. Modern smartphone technology includes accelerometers built into phones, and the vast, global proliferation of smartphones could provide a possible low-cost alternative for assessing kinematic risky driving. …”
Publicado 2018
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54973por Haynsen, Matthew S., Vatanparast, Mohammad, Mahadwar, Gouri, Zhu, Dennis, Moger-Reischer, Roy Z., Doyle, Jeff J., Crandall, Keith A., Egan, Ashley N.“…The vine is highly invasive in its introduced areas, including the southeastern US. Modern molecular marker resources are limited for the species, despite its importance. …”
Publicado 2018
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54974por Diarra, Maryam, Fall, Moussa, Fall, Assane Gueye, Diop, Aliou, Lancelot, Renaud, Seck, Momar Talla, Rakotoarivony, Ignace, Allène, Xavier, Bouyer, Jérémy, Guis, Hélène“…The western part of the country (the Niayes area) concentrates modern farms with exotic horses of high value and was highly affected during the 2007 outbreak that has started in the area. …”
Publicado 2018
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54975por Millar, Kathryn, Patel, Suha, Munson, Meghan, Vesel, Linda, Subbiah, Shalini, Jones, Rachel M, Little, Sarah, Papageorghiou, Aris T, Villar, Jose, Wegner, Mary Nell, Pearson, Nick, Muigai, Faith, Ongeti, Catherine, Langer, Ana“…BACKGROUND: The burden of preterm birth, fetal growth impairment, and associated neonatal deaths disproportionately falls on low- and middle-income countries where modern obstetric tools are not available to date pregnancies and monitor fetal growth accurately. …”
Publicado 2018
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54976por Rosa, João Ricardo Bachega Feijó, Mantello, Camila Campos, Garcia, Dominique, de Souza, Lívia Moura, da Silva, Carla Cristina, Gazaffi, Rodrigo, da Silva, Cícero Casimiro, Toledo-Silva, Guilherme, Cubry, Philippe, Garcia, Antonio Augusto Franco, de Souza, Anete Pereira, Le Guen, Vincent“…CONCLUSIONS: Our results identified a set of significant QTLs for rubber tree, showing that the performance of modern Asiatic cultivars can still be improved and paving the way for further marker-assisted selection, which could accelerate breeding programs. …”
Publicado 2018
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54977por Baichoo, Shakuntala, Souilmi, Yassine, Panji, Sumir, Botha, Gerrit, Meintjes, Ayton, Hazelhurst, Scott, Bendou, Hocine, Beste, Eugene de, Mpangase, Phelelani T., Souiai, Oussema, Alghali, Mustafa, Yi, Long, O’Connor, Brian D., Crusoe, Michael, Armstrong, Don, Aron, Shaun, Joubert, Fourie, Ahmed, Azza E., Mbiyavanga, Mamana, Heusden, Peter van, Magosi, Lerato E., Zermeno, Jennie, Mainzer, Liudmila Sergeevna, Fadlelmola, Faisal M., Jongeneel, C. Victor, Mulder, Nicola“…CONCLUSION: The H3ABioNet workflows have been implemented in view of offering ease of use for the end user and high levels of reproducibility and portability, all while following modern state of the art bioinformatics data processing protocols. …”
Publicado 2018
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54978por Meinert, Edward, Van Velthoven, Michelle, Brindley, David, Alturkistani, Abrar, Foley, Kimberley, Rees, Sian, Wells, Glenn, de Pennington, Nick“…BACKGROUND: Demands on health services across are increasing because of the combined challenges of an expanding and aging population, alongside complex comorbidities that transcend the classical boundaries of modern health care. Continuing to provide and coordinate care in the current manner is not a viable route to sustain the improvements in health outcomes observed in recent history. …”
Publicado 2018
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54979por Egan, Aoife M., Vellinga, Akke, Harreiter, Jürgen, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Adelantado, Juan M., Devlieger, Roland, Van Assche, Andre, Galjaard, Sander, Damm, Peter, Mathiesen, Elisabeth R., Jensen, Dorte M., Andersen, Liselotte, Lapolla, Annuziata, Dalfrà, Maria G., Bertolotto, Alessandra, Mantaj, Urszula, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David, Jelsma, Judith G. M., Snoek, Frank J., Worda, Christof, Bancher-Todesca, Dagmar, van Poppel, Mireille N. M., Kautzky-Willer, Alexandra, Dunne, Fidelma P.“…Uniform criteria for GDM diagnosis, supported by robust evidence for the benefits of treatment, are urgently needed to guide modern GDM screening and treatment strategies.…”
Publicado 2017
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54980por Medrano-Jiménez, Elisa, Jiménez-Ferrer Carrillo, Itzia, Pedraza-Escalona, Martha, Ramírez-Serrano, Cristina E., Álvarez-Arellano, Lourdes, Cortés-Mendoza, Javier, Herrera-Ruiz, Maribel, Jiménez-Ferrer, Enrique, Zamilpa, Alejandro, Tortoriello, Jaime, Pedraza-Alva, Gustavo, Pérez-Martínez, Leonor“…Thus, plants natural products have become an excellent option for modern therapeutics. Malva parviflora is a plant well known for its anti-inflammatory properties. …”
Publicado 2019
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