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  1. 12001
    “…However, in comparison with widely adopted mono-immune checkpoint inhibitors, chemotherapy, and targeted therapy, the advantage of combination therapy of α-PD-1 and α-CTLA-4 in response rate and prognosis is controversial especially considering probably increased treatment related adverse event. …”
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    The efficacy and safety of combination of PD-1 and CTLA-4 inhibitors: a meta-analysis
  2. 12002
    “…Detection of multi- and mono-DR TB in both entrant and resident prisoners warrants regular screening for active TB and adoption of methods to detect drug resistance.…”
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    Bacteriologically-confirmed pulmonary tuberculosis in an Ethiopian prison: Prevalence from screening of entrant and resident prisoners
  3. 12003
    “…Case Report: 33 weeks gestational age mono-chorionic/di-amniotic twins born to a 34-year-old woman with poorly controlled hyperthyroidism. …”
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    SUN-517 Methimazole-Induced Neutropenia in Premature Twins with Graves’ Disease
  4. 12004
    “…To assess the frequency of genetic (mono-, di-, or oligogenic) HP cases, we identified heterozygous variants (regardless of inheritance) in 42 genes previously reported to be associated with pituitary development. …”
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    SAT-289 Evidence That Combined Pituitary Hormone Deficiency Frequently Has a Digenic/Oligogenic Etiology
  5. 12005
    “…This research aims to understand the language learning and social experiences of mono-, bi- and multilingual autistic people. A total of 297 autistic adults (mean age = 32.4 years) completed an online questionnaire including general demographic, language history and social life quality self-rating items. …”
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    Bilingualism in autism: Language learning profiles and social experiences
  6. 12006
    “…Metabolic and mTOR inhibitor mono-treatments had moderate antiproliferative effects in the studied cell lines in a subtype-independent manner, revealing their high adaptive capacity and survival/growth potential. …”
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    In Situ Metabolic Characterisation of Breast Cancer and Its Potential Impact on Therapy
  7. 12007
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    Prior Anticoagulation in Patients with Ischemic Stroke and Atrial Fibrillation
  8. 12008
    “…Bevacizumab maintenance therapy and later cisplatin mono 50 mg/m² q2w led to local and distant tumor progression. …”
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    Diagnostic and Therapeutic Approach in a Metastatic Vaginal Adenocarcinoma: A Case Report
  9. 12009
    “…The AUROC was 0.84 (95%CI: 0.80-0.89), indicating good discrimination of HCV/HIV coinfection and HIV mono-infection. The CPS result ≥0 best fits the test-threshold (negative predictive value: 99.2%, 95%CI: 98.8-99.6). …”
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    Development of a risk score to guide targeted hepatitis C testing among human immunodeficiency virus patients in Cambodia
  10. 12010
    “…Co(2)(Ppz)Cl(4) and {di­chlorido­{4-methyl-1-[2-(pyridin-2-yl)eth­yl]-1,4-di­aza­cyclo­hepta­ne}cobalt(II) [CoCl(2)(C(13)H(21)N(3))] or Co(Pmhpz)Cl(2), crystallize in the monoclinic space group P2(1)/n, while crystals of the penta­coordinate mono­chloro chelate 1,4-bis­[2-(pyr­id­in-2-yl)eth­yl]piperazine}chlorido­cobalt(II) perchlorate, [CoCl(C(18)H(24)N(4))]ClO(4) or [Co(Ppz)Cl]ClO(4), are also monoclinic (P2(1)). …”
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    Chloro­cobalt complexes with pyridyl­ethyl-derived di­aza­cyclo­alkanes
  11. 12011
    “…Current clinical evidence supports LAT alone or in combination with systemic therapies. Our retrospective mono-institutional study aims to assess the role of LAT with a peculiar focus on the largest series of non-oncogene addicted oligometastatic NSCLC patients to date. …”
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    Role of Radiosurgery and Stereotactic Ablative Radiotherapy for Oligometastatic Non-Oncogene Addicted NSCLC
  12. 12012
    “…SIMPLE SUMMARY: Fatty acids, especially the representatives of essential mono- and polyunsaturated ones, play an important role in the human organism, as they are involved in the regulation of the immune and central nervous systems. …”
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    An Environmentally Friendly Approach for the Release of Essential Fatty Acids from Cereal By-Products Using Cellulose-Degrading Enzymes
  13. 12013
    por Goeldlin, Martina B., Mueller, Achim, Siepen, Bernhard M., Mueller, Madlaine, Strambo, Davide, Michel, Patrik, Schaerer, Michael, Cereda, Carlo W., Bianco, Giovanni, Lindheimer, Florian, Berger, Christian, Medlin, Friedrich, Backhaus, Roland, Peters, Nils, Renaud, Susanne, Fisch, Loraine, Niederhaeuser, Julien, Carrera, Emmanuel, Dirren, Elisabeth, Bonvin, Christophe, Sturzenegger, Rolf, Kahles, Timo, Nedeltchev, Krassen, Kaegi, Georg, Vehoff, Jochen, Rodic, Biljana, Bolognese, Manuel, Schelosky, Ludwig, Salmen, Stephan, Mono, Marie-Luise, Polymeris, Alexandros A., Engelter, Stefan T., Lyrer, Philippe, Wegener, Susanne, Luft, Andreas R., Z’Graggen, Werner, Bervini, David, Volbers, Bastian, Dobrocky, Tomas, Kaesmacher, Johannes, Mordasini, Pasquale, Meinel, Thomas R., Arnold, Marcel, Fandino, Javier, Bonati, Leo H., Fischer, Urs, Seiffge, David J.
    Publicado 2022
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    Etiology, 3-Month Functional Outcome and Recurrent Events in Non-Traumatic Intracerebral Hemorrhage
  14. 12014
    “…Individuals with an O. viverrini mono-infection displayed both increases and decreases in genera present in their faecal microbiota, while increases in three families and one order were also observed in these samples. …”
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    Clinical helminth infections alter host gut and saliva microbiota
  15. 12015
    “…INTRODUCTION: We report on the in vitro and ex vivo effects of chiral (R)‐10‐hydroxystearic acid (10‐HSA) compared with other mono‐hydroxystearic acid regioisomers and stearic acid (SA) together with its benefit when combined with retinol. …”
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    Effect of regioisomers of hydroxystearic acids as peroxisomal proliferator‐activated receptor agonists to boost the anti‐ageing potential of retinoids
  16. 12016
    “…Additionally considering the network connectivity of these sites (i.e., the wider set of brain regions that may be mono- or poly-synaptically activated by TMS stimulation) has the potential to improve subject-specificity of TMS targeting and, in turn, improve treatment outcomes. …”
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    Mapping Inter-individual Functional Connectivity Variability in TMS Targets for Major Depressive Disorder
  17. 12017
    “…[Image: see text] Low-cost mesoporous silicas of the SBA-15 family were prepared, aimed for removal of a broad spectrum of both cationic and anionic forms of hazardous metal pollutants (Cr(III, VI), Mn(II, VII), Pb(II), Cd(II), and Cu(II)) from environmental water. Series of mono- and bifunctional materials with immobilized ethylenediaminetriacetic acid (EDTA), primary amine (NH(2)), and quaternary ammonium (QAS) groups were prepared in a cost-efficient one-step synthesis using two silica sources, low-cost sodium metasilicate (Na(2)SiO(3) 9H(2)O) and the conventional source—tetraethylorthosilicate (TEOS). …”
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    In situ Functionalized Mesoporous Silicas for Sustainable Remediation Strategies in Removal of Inorganic Pollutants from Contaminated Environmental Water
  18. 12018
    “…MATERIALS AND METHODS: A retrospective cohort of singleton pregnancies with eoPE and attempted expectant management between 2014 and 2020. A Mono-objective Genetic Algorithm based on supervised classification models was implemented to develop D and HA models. …”
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    Prediction of Delivery Within 7 Days After Diagnosis of Early Onset Preeclampsia Using Machine-Learning Models
  19. 12019
    “…Herein we give an account of our work on several families of iridium complexes typically equipped with two cyclometalating bidentate ligands (C(∧)N), in combination with mono or bidentate “ancillary” ligands with N(∧)N, C(∧)N, and C(∧)C motifs. …”
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    Excited-State Engineering in Heteroleptic Ionic Iridium(III) Complexes
  20. 12020
    “…Whatever the details of the prevention strategy that is adopted (ie, how a mono- or multifactorial intervention is evaluated, the category of person the intervention targets, and where it is used), it is important to ensure that the proposed intervention is feasible and usable for the patient and the health care team. …”
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    Physical Activity and Fall Prevention in Geriatric Inpatients in an Acute Care Unit (AGIR Study): Protocol for a Usability Study
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