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  1. 12041
    por Eleje, George Uchenna, Mbachu, Ikechukwu Innocent, Ogwaluonye, Uchenna Chukwunonso, Kalu, Stephen Okoroafor, Onubogu, Chinyere Ukamaka, Nweje, Sussan Ifeyinwa, Uzochukwu, Chinwe Elizabeth, Nwankwo, Chike Henry, Fiebai, Preye Owen, Loto, Olabisi Morebise, Akaba, Godwin Otuodichinma, Usman, Hadiza Abdullahi, Rabiu, Ayyuba, Egeonu, Richard Obinwanne, Igue, Odion Emmanuel, Adesoji, Bukola Abimbola, Jibuaku, Chiamaka Henrietta, Aja, Prince Ogbonnia, Chidozie, Chiamaka Perpetua, Ibrahim, Hadiza Sani, Aliyu, Fatima Ele, Numan, Aisha Ismaila, Okoro, Ogbonna Dennis, Omoruyi, Solace Amechi, Oppah, Ijeoma Chioma, Anyang, Ubong Inyang, Ahmed, Aishat, Chukwurah, Shirley Nneka, Umeononihu, Osita Samuel, Chukwuanukwu, Rebecca Chinyelu, Umeh, Eric Okechukwu, Emeka, Ekene Agatha, Ogbuagu, Chukwuanugo Nkemakonam, Yakasai, Ibrahim Adamu, Ezechi, Oliver Chukwujekwu, Ikechebelu, Joseph Ifeanyichukwu
    Publicado 2020
    “…Although some limited data on mono infection of HIV, Hepatitis B and C virus infections do exists, that of dual and triplex infections, including seroconversion and mother-to-child transmission (MTCT) rates necessary for planning to address the scourge of infections in pregnancy are not available. …”
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    Prevalence, seroconversion and mother-to-child transmission of dual and triplex infections of HIV, hepatitis B and C viruses among pregnant women in Nigeria: study protocol
  2. 12042
    “…CONCLUSION: Gliclazide or gliclazide + metformin prescribed as mono- or add-on therapy during routine clinical practice effectively reduced HbA1c in Indian patients with T2DM, thus validating the use of gliclazide and gliclazide + metformin for managing T2DM in India.…”
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    Effect of Gliclazide or Gliclazide plus Metformin Combination on Glycemic Control in Patients with T2DM in India: A Real-World, Retrospective, Longitudinal, Observational Study from Electronic Medical Records
  3. 12043
    “…Genotypes were successfully translated into haplotypes in 2694 and 846 mono infections respectively for pfdhfr and pfdhps genes and the combined pfhdfr/pfdhps genes across all years. …”
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    Temporal evolution of sulfadoxine-pyrimethamine resistance genotypes and genetic diversity in response to a decade of increased interventions against Plasmodium falciparum in northern Ghana
  4. 12044
    “…The secondary outcome was the pooled risk ratio (RR) of malarial recurrence in Plasmodium-mixed infection compared with those in Plasmodium falciparum and Plasmodium vivax mono-infection. The pooled analyses were calculated by random-effects meta-analysis. …”
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    The high risk of malarial recurrence in patients with Plasmodium-mixed infection after treatment with antimalarial drugs: a systematic review and meta-analysis
  5. 12045
    por Bukowy-Bieryłło, Zuzanna
    Publicado 2021
    “…The review compares the CRC HAE technique variants (feeder culture or HAE mono-culture), based on recently published studies exploiting this model. …”
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    Long-term differentiating primary human airway epithelial cell cultures: how far are we?
  6. 12046
    “…Serotyping by nested RT-PCR revealed mostly mono-infections with DENV-2 (n = 64), DENV-1 (n = 32) and DENV-3 (n = 17); 14 co-infections occurred with DENV-1/DENV-2 (n = 13) and DENV-1/DENV-4 (n = 1). …”
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    Rapid testing requires clinical evaluation for accurate diagnosis of dengue disease: A passive surveillance study in Southern Malaysia
  7. 12047
    “…The top 50 also included several food additives for which potential adverse health effects have been suggested by recent experimental studies: lecithins (86.6% consumers), mono- and diglycerides of fatty acids (78.1%), carrageenan (77.5%), sodium nitrite (73.9%), di-, tri- and polyphosphates (70.1%), potassium sorbate (65.8%), potassium metabisulphite (44.8%), acesulfame K (34.0%), cochineal (33.9%), potassium nitrate (31.6%), sulfite ammonia caramel (28.8%), bixin (19.5%), monosodium glutamate (15.1%) and sucralose (13.5%). …”
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    Exposure to food additive mixtures in 106,000 French adults from the NutriNet-Santé cohort
  8. 12048
    “…In the SS group 5 patients (1 PR, 3 progressive disease and 1 relapse) received concomitant t treatment with INF alfa 2b, bexarotene and electron beam; the relapsed patient underwent mono chemotherapy. Three patients were infected with SARS-CoV-2, all of them were from the SS group, the contagion was outside the hospital environment. …”
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    Extracorporeal photopheresis during the COVID-19 pandemic: experience in Argentina
  9. 12049
    “…Patients received further three cycles of durvalumab/tremelimumab followed by eight cycles of durvalumab mono (every 4 weeks). The intended treatment for patients not meeting these criteria was standard radiochemotherapy outside the trial. …”
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    Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in locally advanced head and neck cancer
  10. 12050
    “…A fully adjusted Cox model showed that a urinary di(2-ethylhexyl) phthalate (DEHP) concentration >= 83.4 ng/mL was associated with a slight increase in all-cause mortality (HR 1.27, 95% CI 1.03, 1.57, P for trend= 0.014) and CVD mortality (HR 2.19, 95% CI 1.35, 3.54, P for trend= 0.002). Similarly, urinary mono-2-ethyl-5-carboxypentyl phthalate (MECPP) levels >= 39.2 ng/mL were associated with increased CVD mortality (HR 2.33, 95% CI 1.45, 3.73, P for trend < 0.001). …”
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    Low-level plasticizer exposure and all-cause and cardiovascular disease mortality in the general population
  11. 12051
    “…During metabolism, iAs is sequentially methylated to mono- and di-methylated arsenical species (MMAs and DMAs) to facilitate whole body clearance. …”
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    Maternal serum concentrations of one-carbon metabolism factors modify the association between biomarkers of arsenic methylation efficiency and birth weight
  12. 12052
    “…CONCLUSIONS: The updated mathematical model can predict the growth and clearance of PfHRP2 during the production and decay of a mono-infection with P. falciparum, increasing the understanding of PfHRP2 antigen dynamics. …”
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    The in-vivo dynamics of Plasmodium falciparum HRP2: implications for the use of rapid diagnostic tests in malaria elimination
  13. 12053
    “…Therefore this study aims to evaluate the feasibility and effectiveness of time-limited EMDR therapy in reducing PTSD symptoms, comorbid psychological symptoms, distress, and parental stress. METHODS: Mono-center randomized clinical trial conducted between February 2020 and April 2021. …”
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    Effectiveness of time-limited eye movement desensitization reprocessing therapy for parents of children with a rare life-limiting illness: a randomized clinical trial
  14. 12054
    “…Patients had a greater estimated 30 days percent reduction in anti-RBD levels compared to controls − 4.9 (95% CI − 7.4 to − 2.4), (p<0.05). Among therapies, mono- or combination treatment with tumor necrosis factor inhibitors was associated with the greatest decline. …”
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    The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls—a prospective cohort study
  15. 12055
    “…RESULTS: Samples were collected prior to antimalarial treatment from 127 patients with microscopy-positive PCR-confirmed P. knowlesi mono-infections. Median parasitaemia was 788/µL (IQR 247-5,565/µL). …”
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    Diagnostic accuracy and limit of detection of ten malaria parasite lactate dehydrogenase-based rapid tests for Plasmodium knowlesi and P. falciparum
  16. 12056
    “…Based on RF, 10 features with the highest relative importance were selected as the best influential features; including blood urea nitrogen (BUN), lymphocytes (Lym), age, blood sugar (BS), serum glutamic-oxaloacetic transaminase (SGOT), monocytes (Mono), blood creatinine (CR), neutrophils (NUT), alkaline phosphatase (ALP) and hematocrit (HCT). …”
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    Interpretable generalized neural additive models for mortality prediction of COVID-19 hospitalized patients in Hamadan, Iran
  17. 12057
    “…In the low PD-L1 (TS <50%) cohort, TMB <20 muts/Mb showed a more favorable rwPFS (HR: 0.56 (95% CI: 0.40 to 0.79)) and rwOS (HR 0.74 (95% CI: 0.58 to 0.96)) on chemoICPI when compared with ICPI alone while the point estimate in rwPFS favored monoICPI in the TMB ≥20 muts/Mb cohort, the CI is wide and does not reach statistical significance (HR: 1.68 (95% CI: 0.52 to 5.48)). …”
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    Durable responders in advanced NSCLC with elevated TMB and treated with 1L immune checkpoint inhibitor: a real-world outcomes analysis
  18. 12058
    por Scarlatti, Domenico, 1685-1757
    Publicado 1993
    CD Audiom
    Sonatas
  19. 12059
    “…[Zn{O(2)P(OPh)(2)}(2)](∞) (1), formed from the reaction of Zn[N(SiMe(3))(2)](2) with HO(O)P(OPh)(2) coordinates to donor-base ligands, i.e., pyridine (Py), 4-methylpyridine (4-MePy), 2,2-bipyridine (bipy), tetramethylethylenediamine (TMEDA), pentamethyldiethylenetriamine (PMDETA), and 1,3,5-trimethyl-1,3,5-triazacyclohexane (Me(3)-TAC), to produce polymeric 1D structures, [(Py)(2)Zn{O(2)P(OPh)(2)}(2)](∞) (2) and [(4-MePy)(2)Zn{O(2)P(OPh)(2)}(2)](∞) (3), the bimetalic systems, [(Bipy)Zn{O(2)P(OPh)(2)}(2)](2) (4), [(TMEDA)Zn{O(2)P(OPh)(2)}(2)](2) (5), and [(Me(3)-TAC)Zn{O(2)P(OPh)(2)}(2)](2) (7), as well as a mono-nuclear zinc bis-diphenylphosphate complex, [(PMDETA)Zn{O(2)P(OPh)(2)}(2)] (6). (1)H NMR DOSY has been used to calculate averaged molecular weights of the species. …”
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    Exploration of Solid-State vs Solution-State Structure in Contact Ion Pair Systems: Synthesis, Characterization, and Solution-State Dynamics of Zinc Diphenyl Phosphate, [Zn{O(2)P(OPh)(2)}(2)], Donor-Base-Supported Complexes
  20. 12060
    “…Synergy was most detected in ESBL producers (32% of combinations; Figure 2) and less frequently in CPEs (2% combinations) and fully susceptible isolates (4% combinations). 31/630 (5%) combinations showed improvement in EUCAST susceptibility between mono/combination therapy (according to our definitions). …”
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    P11 Evaluation of in vitro activity of double β-lactam ‘therapy’ in Escherichia coli: what is the association between ‘synergy’ and in vitro susceptibility?
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