“…Disruptor of telomeric silencing-1-like (DOT1L), also known as KMT4, is the only identified histone methyltransferase that catalyzes the mono-, di-, and tri-methylation of lysine 79 histone 3 (H3K79). …”
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“…The use of the Er:YAG laser alone failed to show statistically significant antibacterial activity against any of bacteria. The most effective mono-treatment with irrigation solutions for all three bacteria were 0.5% H(2)O(2) and 0.5% NaOCl (p < 0.001 for each solution). …”
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“…By stepwise comparison of CUDC-907 with mono-functional PI3K and HDAC inhibitors, we demonstrated that CUDC-907 exerts its inhibitory effect on ACTH secretion primarily through its inhibition of HDAC activity at the POMC transcriptional level; while PI3K-mediated inhibition of corticotroph cell viability further contributes to reduced ACTH secretion. …”
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“…Most reports of cortisol half-life in the literature report a range of 90-130 min, which results are based on descriptive model that assumes mono-exponential decay of a single, total cortisol compartment. …”
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“…Those who started treatment with mono/dual antiretroviral therapy, had a history of treatment interruption >14 days, or received treatment and care at sites with a pVL lower limit of detection >50 copies/mL were excluded. …”
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“…The factors analysed were age of referral, ratio of boys to girls, mono‐ and bilingualism, nature of the language delay, and language profile of the children. …”
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“…Four sub-cohorts were constituted: mono-therapy - group A (n=70, ACEI/ARB), dual-therapy - group B (n=48, ACEI/ARB+TD) and  group C (n=51, ACEI/ ARB+CCB), triple therapy - group D (n=48, ACEI/ ARB+TD+CCB). …”
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“…Lumbar puncture CSF pro 0.38, white cells 12 (poly 50%, mono 50%), red cells 3700, no organisms on gram stain, opening pressure 21.5 cmH(2)O. …”
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“…Reaction of H(4)L1 with Hg(NO(3))(2) in the presence of a potassium acetate buffer did not produce the expected binuclear complex, instead crystals of a potassium–organic framework were obtained, poly[(μ-3-{[(3,5,6-tris­{[(2-carb­oxy­eth­yl)sulfan­yl]meth­yl}pyrazin-2-yl)meth­yl]sulfan­yl}propano­ato)potassium], [K(C(20)H(27)N(2)O(8)S(4))](n) (KH(3)L1). The organic mono-anion possesses inversion symmetry with the pyrazine ring being located about an inversion center. …”
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“…The metric FP (P95th) derived from IVIM performed better in determining Lauren classifications than the mono-exponential model.…”
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“…Results: The green-mediated synthesis of AgNPs using P. niveum methanolic extract produced spherical and mono-dispersed NPs with a size ranging from 12 to 28 nm (average: 21 nm). …”
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“…The Weibull moduli for the [(0((E-glass)))/(0((IMS60)))](S), [(0((E-glass)))/(0((IMS60)))(2)](S), [(0((E-glass)))/(0((IMS60)))(3)](S), [(0((E-glass)))/(0((IMS60)))(5)](S), [(0((E-glass)))(2)/(0((IMS60)))](S), [(0((E-glass)))(3)/(0((IMS60)))](S), and [(0((E-glass)))(5)/(0((IMS60)))](S) HFRP specimens were higher than those for the mono carbon fiber-reinforced epoxy (CFRP) and glass fiber-reinforced epoxy (GFRP) specimens. …”
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“…They were further grouped according to their serological status in four categories: 121 Human T cell Leukemia Virus type 1 asymptomatic mono-infected carriers; 32 Human T cell Leukemia Virus type 1/Hepatitis C Virus, 29 Human T cell Leukemia Virus type 1/Human Immunodeficiency Virus type 1, and 19 Human T cell Leukemia Virus type 1/Human Immunodeficiency Virus type 1/Hepatitis C Virus co-infected patients. …”
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“…Multiple cropping increased MAOC, MBC and EOC by 14.1%, 39.8% and 21.5%, respectively, compared to mono cropping (P < 0.05). The response ratios of SOC fractions (MAOC, MAOM, SOC, MBC, EOC and POC) under NT and RT were mostly influenced by NBS such as residue management, cropping pattern along with soil depth, mean annual precipitation, mean annual temperature and soil texture. …”
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“…While this study may demonstrate a new function for AMH, the biological purpose of this function requires further investigation, particularly in mono-ovulatory species. STUDY FUNDING/COMPETING INTEREST(S): This study was funded by the Health Research Council of New Zealand and the University of Otago. …”
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“…A considerable proportion of bacterial isolates exhibited mono and/or multi-drug resistance. Age (15–64 years), being farmer, previous history of eye surgery and less frequency of face washing were significantly associated with the prevalence of culture-confirmed bacteria. …”
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“…[Formula: see text] O(2) and Δdeoxy[heme] responses during workrate-transitions to moderate-intensity cycling were measured with breath-by-breath spirometry and near-infrared spectroscopy, respectively, and subsequently modeled with mono-exponential models to derive parameter estimates. …”
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“…MATERIAL AND METHODS: Twenty-four mono-institutional consecutive treatment plans (50 Gy/25 fx) delivered between November 2019 and April 2022 were retrospectively selected. …”
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“…Among the PCR positive samples (n=245), 32.7% were poly-microbial (n=80) and 67.3% were mono-microbial (n=165). In comparison, among culture positive samples (n=183), 33.3% (n=61) were polymicrobial and 65.6% (n=120) monomicrobial. …”
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“…Monocultures of SF-FLSs (n = 6) and autologous co-cultures of SF-FLSs and peripheral blood mononuclear cells (PBMCs) were cultured with and without a neutralizing anti-Gal-9 antibody (n = 7). The mono- and co-cultures were subsequently analyzed by flow cytometry, MTT assay, and ELISA. …”
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