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12141“…In addition, priming with a mono-epitope carrier (RAT) is sufficient preparation for IgG responses to a trifunctional immunogen. …”
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12142por Chamberlain, Amanda J., Vander Jagt, Christy J., Hayes, Benjamin J., Khansefid, Majid, Marett, Leah C., Millen, Catriona A., Nguyen, Thuy T. T., Goddard, Michael E.“…For example the gene SPTY2D1 showed almost complete paternal allele expression in kidney and thymus, and almost complete maternal allele expression in the brain caudal lobe and brain cerebellum. Mono allelic expression (MAE) was common, with 1349 of 4856 genes (28 %) tested with more than one heterozygous SNP showing MAE. …”
Publicado 2015
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12143por Abreha, Tesfay, Hwang, Jimee, Thriemer, Kamala, Tadesse, Yehualashet, Girma, Samuel, Melaku, Zenebe, Assef, Ashenafi, Kassa, Moges, Chatfield, Mark D., Landman, Keren Z., Chenet, Stella M., Lucchi, Naomi W., Udhayakumar, Venkatachalam, Zhou, Zhiyong, Shi, Ya Ping, Kachur, S. Patrick, Jima, Daddi, Kebede, Amha, Solomon, Hiwot, Mekasha, Addis, Alemayehu, Bereket Hailegiorgis, Malone, Joseph L., Dissanayake, Gunewardena, Teka, Hiwot, Auburn, Sarah, von Seidlein, Lorenz, Price, Ric N.“…METHODS AND FINDINGS: Patients with normal glucose-6-phosphate dehydrogenase status with symptomatic P. vivax mono-infection were enrolled and randomly assigned to receive either chloroquine (CQ) or artemether-lumefantrine (AL), alone or in combination with 14 d of semi-supervised primaquine (PQ) (3.5 mg/kg total). …”
Publicado 2017
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12144por Grigg, Matthew J, Cox, Jonathan, William, Timothy, Jelip, Jenarun, Fornace, Kimberly M, Brock, Patrick M, von Seidlein, Lorenz, Barber, Bridget E, Anstey, Nicholas M, Yeo, Tsin W, Drakeley, Christopher J“…FINDINGS: From Dec 5, 2012, to Jan 30, 2015, we screened 414 patients and subsequently enrolled 229 cases with P knowlesi malaria mono-infection and 91 cases with other Plasmodium spp infection. …”
Publicado 2017
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12145“…Six single-nucleotide-repeat markers of microsatellite instability (MSI), including NR-27, MONO-27, BAT-25, NR-24, NR-21, and BAT-26, were tested by capillary electrophoresis sequencer analysis. …”
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12146por Legind, Christian, Broberg, Brian, Mandl, Rene, Brouwer, Rachel, Anhøj, Simon, Hilker, Rikke, Jensen, Maria H, McGuire, Philip, Hulshoff Pol, Hilleke E, Fagerlund, Birgitte, Rostrup, Egill, Glenthoj, Birte“…By studying discordant mono- (MZ) and dizygotic (DZ) twins it is possible to estimate heritability and correlation to disease in the same population. …”
Publicado 2018
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12147por Rockstroh, Jurgen K, Bhagani, Sanjay R, Orkin, Chloe, Soto-Malave, Ruth, Lacombe, Karine, Zhang, Zhenzhen, Wang, Stanley, Mensa, Federico, Trinh, Roger“…The once-daily, all-oral, ribavirin-free, pangenotypic combination of glecaprevir (identified by AbbVie and Enanta) and pibrentasvir has shown high sustained virologic response at post-treatment Week 12 (SVR12) in HCV mono-infected patients. We evaluated the safety/efficacy of glecaprevir/pibrentasvir in patients co-infected with HCV/HIV-1. …”
Publicado 2018
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12148por Charalambous, Maria, Moushi, Eleni E., Nguyen, Tu N., Papatriantafyllopoulou, Constantina, Nastopoulos, Vassilios, Christou, George, Tasiopoulos, Anastasios J.“…The structure of 1 consists of a mixed valence [[Formula: see text] [Formula: see text] [Formula: see text]](2−) molecular aggregate that contains two [Formula: see text] [Formula: see text] loops separated by two [Formula: see text] [Formula: see text] supertetrahedral units and a [[Formula: see text] [Formula: see text]](2+) cation based on two [Mn(III) [Formula: see text] (μ(4)-O)(μ(3)-OH)(1.5)(μ(3)-Cl)(1.5)](4+) cubane sub-units connected through both mono- and tri-atomic bridges provided by the μ(4)-O(2−) and carboxylate anions. …”
Publicado 2019
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12149por Manful, Charles F., Vidal, Natalia P., Pham, Thu H., Nadeem, Muhammad, Wheeler, Evan, Hamilton, Melissa C., Doody, Karen M., Thomas, Raymond H.“…The effect of marination on the fatty acid profile, including saturated, mono- and polyunsaturated fatty acids, of grilled meat was analyzed by gas chromatography/mass spectrometry (GC/MS). …”
Publicado 2019
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12150
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12151por Mahler, Michael, Kim, Grace, Roup, Fabrece, Bentow, Chelsea, Fabien, Nicole, Goncalves, David, Palterer, Boaz, Fritzler, Marvin J., Villalta, Danilo“…Although most anti-fibrillarin positive samples were mono-specific (69.8%), some expressed additional antibodies (namely Scl-70, centromere, dsDNA, Ro52, Ro60, SS-B, Ribo-P, DFS70, and EJ). …”
Publicado 2021
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12152“…The maximum effect of exposure concentration ofPM(2.5) on MONO is reached when the lag accumulation is 3d (Lag2). …”
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12153por Junior, FJ, Scharff, IC, Paulo, LD, Oliveira, AN, Zanella, CYS, Macêdo, RBF, Barbosa, CM, Mileo, MG, Almeida, GE, Scharff, IC, Scharff, IC“…HCM 37,5; CHCM 37,5; RDW 18,5%; Leucócitos: 2800; BAST: 2%; SEGMEN: 40%; LINF 56%; EOSI 1%; MONO: 1%; PLAQ 149.000; DHL 1.920U/L; PCR 12,7. FERRITINA 339 ALT: 23, AST: 31. …”
Publicado 2021
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12154“…CONCLUSION: La période pandémique actuelle permet de souligner l’intérêt majeur de structures intermédiaires comme les USIR au sein des structures hospitalières avec des équipes formées aux prises en charges de la défaillance mono-organe respiratoire.…”
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12155“…Regardless of evidence of sporadic efficacy reduction reported in the country, chloroquine (CQ), the first-line regimen in Ethiopia, remained highly efficacious, supporting its continuous utilization for confirmed P. vivax mono-infections. The addition of primaquine (PQ) to CQ is recommended, as this is the only approved way to provide radical cure, and thus ensure sustained efficacy and longer protection against P. vivax. …”
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12156por Stone, William, Mahamar, Almahamoudou, Sanogo, Koualy, Sinaba, Youssouf, Niambele, Sidi M, Sacko, Adama, Keita, Sekouba, Youssouf, Ahamadou, Diallo, Makonon, Soumare, Harouna M, Kaur, Harparkash, Lanke, Kjerstin, ter Heine, Rob, Bradley, John, Issiaka, Djibrilla, Diawara, Halimatou, Traore, Sekou F, Bousema, Teun, Drakeley, Chris, Dicko, Alassane“…Participants were aged 5–50 years, with asymptomatic P falciparum malaria mono-infection and gametocyte carriage on microscopy, haemoglobin density of 9·5 g/dL or higher, bodyweight less than 80 kg, and no use of antimalarial drugs over the past week. …”
Publicado 2022
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12157por Rabelo, Barbara Lenoir, Aspahana, Maíra Cardoso, Barbosa, Gerdson Magno, Campos, João Paulo Ramos, Pereira, João Lucas Lana, Velloso, Leonardo de Assis Freitas, Bragato, Alexandre Mauricio Castro, de Oliveira, Neimy Ramos“…Punção lombar em 17/07/21: 5 células (96% linf; 1% mono; 3% seg), 213 hemácias, proteína 28mg/dL, glicose 95mg/dL, ausência de microrganismos no Gram, culturas negativas, VDRL não reagente, BAAR negativo e PCR SARS-CoV-2 positivo no líquor. …”
Publicado 2022
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12158“…On the one hand, according to the above information and the different positions and degree of quinic acid esterification, the CGAs were structurally classified as monosubstituted CGAs (Mono-CGAs), disubstituted CGAs (Di-CGAs), and trisubstituted CGAs (Tri-CGAs), and three different mass defect filtering windows were set. …”
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12159“…The early and maturing biofilms enable the Candida cells to overcome the effects of azoles and exhibit higher drug resistance. Since simple azole mono-therapy rarely eradicates recalcitrant Candida biofilms, removal of the infected device becomes necessary for curing the infection. …”
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12160por Alzahrani, Ali, Nafisah, Abdulghani Bin, Alswailem, Meshael, Alsaihati, Burair, Alnassar, Anhar, Bin Afeef, Ahmed, AlQuraa, Reem, Alsuhaibani, Rawan, Alhadlaq, Omar, Altwaijry, Yasser A, Abothenain, Fayha, AlBaz, Batoul, Aljafar, Hussein, Moria, Yosra, Butt, Mohammad Imran, Alkabbani, Abdulrahman Ghiatheddin, Alshaikh, Omalkhaire M“…Most of these variants are mono-allelic (96.25%). These variants were found in the following genes: GNAS (10 variants in 39 pts), AIP (one variant in 1 patient), CDKN1B (2 variants in 2 pts), DICER1 (1 variant in 1 patient), MEN1 (2 variants in 3 pts), NF1 (3 variants in 3 pts), PIK3CA (1 variant in 1 patient), SDHA (3 variants in 3 pts), SDHAF2 (2 variants in 5 pts), SDHB (4 variants in 3 pts), SDHD (3 variants in 3 pts), USP48 (2 variants in 8 pts) and USP8 (1 variant in 1 patient). …”
Publicado 2022
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