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Mostrando 261 - 280 Resultados de 1,213 Para Buscar '"motor neurone disease"', tiempo de consulta: 0.19s Limitar resultados
  1. 261
    “…Motor neuron disease (MND) patients often experience hand-wrist muscle atrophy resulting in severe social consequences and hampering their daily activities. …”
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    Computational Mechanics of Form-Fitting 3D-Printed Lattice-Based Wrist-Hand Orthosis for Motor Neuron Disease
  2. 262
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    A motor neuron disease–associated mutation in p150(Glued) perturbs dynactin function and induces protein aggregation
  3. 263
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    Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: Implications for human motor neuron disease
  4. 264
    “…OBJECTIVES: To examine the frequency and risk factors of cognitive and anxiety-depressive disorders in patients with amyotrophic lateral sclerosis/motor neuron disease (ALS/MND). METHODS: This was an observational study of 100 ALS/MND patients treated at our hospital outpatient and inpatient departments between January 2009 and April 2010 and 100 matched healthy controls. …”
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    Frequency and risk factor analysis of cognitive and anxiety-depressive disorders in patients with amyotrophic lateral sclerosis/motor neuron disease
  5. 265
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    Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases
  6. 266
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    Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS)
  7. 267
    “…Motor neuron disease (MND) is a fatal progressive neurodegenerative disorder characterized by the breakdown of the motor system. …”
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    White Matter Microstructure Breakdown in the Motor Neuron Disease Spectrum: Recent Advances Using Diffusion Magnetic Resonance Imaging
  8. 268
    “…Our results demonstrate that ALS serum can transfer motor neuron disease to mice.…”
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    Experimental Motor Neuron Disease Induced in Mice with Long-Term Repeated Intraperitoneal Injections of Serum from ALS Patients
  9. 269
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    Progressive brainstem pathology in motor neuron diseases: Imaging data from amyotrophic lateral sclerosis and primary lateral sclerosis
  10. 270
    “…To investigate the prognostic role and the major determinants of serum phosphorylated neurofilament heavy -chain (pNfH) concentration across a large cohort of motor neuron disease (MND) phenotypes. Enzyme-linked immunosorbent assay (ELISA) was used to measure serum pNfH concentration in 219 MND patients consecutively enrolled in our tertiary MND clinic. …”
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    Serum phosphorylated neurofilament heavy-chain levels reflect phenotypic heterogeneity and are an independent predictor of survival in motor neuron disease
  11. 271
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    A Spontaneous Lower Motor Neuron Disease Apparently Caused by Indigenous Type-C RNA Virus in Wild Mice
  12. 272
    “…While the thalamus consists of dozens of anatomically well-defined nuclei with distinctive physiological roles, existing imaging studies in motor neuron diseases typically evaluate the thalamus as a single structure. …”
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    “Switchboard” malfunction in motor neuron diseases: Selective pathology of thalamic nuclei in amyotrophic lateral sclerosis and primary lateral sclerosis
  13. 273
    “…Early differential diagnosis of several motor neuron diseases (MNDs) is extremely challenging due to the high number of overlapped symptoms. …”
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    Using blood data for the differential diagnosis and prognosis of motor neuron diseases: a new dataset for machine learning applications
  14. 274
    “…Motor neuron disease (MND) is a rare group of disorders characterized by degeneration of motor neurons (MNs). …”
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    Diagnostic and prognostic value of CSF neurofilaments in a cohort of patients with motor neuron disease: A cross‐sectional study
  15. 275
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    Mills’ syndrome is a unique entity of upper motor neuron disease with N-shaped progression: Three case reports
  16. 276
    “…Neuroimaging assessment of motor neuron disease has turned into a cornerstone of its clinical workup. …”
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    Simultaneous PET/MRI: The future gold standard for characterizing motor neuron disease—A clinico-radiological and neuroscientific perspective
  17. 277
    “…OBJECTIVES: The lack of systematic evidence on neuroimaging findings in motor neuron diseases (MND) hampers the diagnostic utility of magnetic resonance imaging (MRI). …”
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    Structural magnetic resonance imaging findings and histopathological correlations in motor neuron diseases—A systematic review and meta-analysis
  18. 278
    “…Two genes in this segment, NOTCH3 and Safb/SAFB1, have been associated with motor neuron disease. The identification of genetic modifiers of motor neuron disease, especially those modifiers that are shared by SOD1 and dynactin-1 transgenic mice, may result in the identification of novel targets for therapies that can alter the course of this devastating illness.…”
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    Identification of quantitative trait loci for survival in the mutant dynactin p150Glued mouse model of motor neuron disease
  19. 279
    “…BACKGROUND AND PURPOSE: The heterogeneity of cognitive and behavioural disturbances in frontotemporal dementia–motor neuron disease (FTD‐MND), and clinical differences between FTD‐MND and FTD subtypes, have been illustrated cross‐sectionally. …”
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    Distinct disease trajectories in frontotemporal dementia–motor neuron disease and behavioural variant frontotemporal dementia: A longitudinal study
  20. 280
    “…Background: Fatigue is one of the most frequent complaints in patients with motor neuron diseases (MNDs), with a significant impact on the quality of life (QOL). …”
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    The effect of energy conservation strategies on fatigue, function, and quality of life in adults with motor neuron disease: Randomized controlled trial
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