“…Post-polio syndrome (PPS) is characterized by recrudescence or worsening of motor neuron disease symptoms decades after recovery from acute paralytic poliovirus infection, i.e., poliomyelitis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Amyotrophic lateral sclerosis (ALS) is the most well-known form of motor neuron diseases in which both upper and lower motor neurons are involved in this disease. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: Sugammadex can be used successfully to reverse neuromuscular blockade in patients with motor neuron disease.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Although rare, respiratory muscle function failure can be the first symptom of motor neuron disease. Therefore, a motor neuron disease such as ALS, which leads to respiratory muscle weakness and diaphragm paralysis, should be considered in cases of unexplained acute respiratory failure.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…One patient developed amyotrophy and thus a picture of amyotrophic lateral sclerosis after 16 years, suggesting that Mills’ syndrome is part of the motor neuron disease spectrum. Both amyotrophy and subclinical contralateral upper motor neuron disease can therefore be features of Mills’ syndrome. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease with no cure. Currently there are only two ALS drugs approved by the FDA, both with a limited therapeutic effect. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Identifying methods for incorporating job-exposure matrices and nonoccupational risk factors could further enhance interpretations for some findings such as motor neuron disease.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A group of 13 patients with motor neuron disease underwent liver imaging and laboratory analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease classified as both a neurodegenerative and neuromuscular disorder. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in the adulthood, and it is characterized by rapid and progressive compromise of the upper and lower motor neurons. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Motor neuron diseases such as amyotrophic lateral sclerosis are primarily characterized by motor neuron degeneration with additional involvement of non-neuronal cells, in particular, microglia. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The wobbler mouse is an animal model for human motor neuron disease, such as amyotrophic lateral sclerosis (ALS). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In family 2, a novel VRK1 mutation, c.403G>A; p.G135R and c.583T>G; p.L195V, were identified in a child with motor neuron disease. CONCLUSIONS: VRK1 mutations can produce adult-onset SMA and motor neuron disease in children without pontocerebellar hypoplasia.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Keywords included Cognitive Impairment, Neuromuscular Diseases, Motor Neuron Diseases, Dystrophinopathies and Mitochondrial Disorders. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Spinal muscular atrophy (SMA) is an autosomal recessive motor neuron disease of variable clinical severity that is caused by mutations in the survival motor neuron 1 (SMN1) gene. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Careful clinical correlation is necessary to distinguish crural MMA from other motor neuron diseases. When crural MMA is diagnosed, treatment options aim to alleviate symptoms.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also compare ALS to other motor neuron diseases and draw perspectives for future research and treatment.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Amyotrophic lateral sclerosis (ALS), the most frequent adult onset motor neuron disease, is associated with hypermetabolism linked to defects in muscle mitochondrial energy metabolism such as ATP depletion and increased oxygen consumption. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we show that membralin mutant mice manifest a severe and early-onset motor neuron disease in an autosomal recessive manner, dying by postnatal day 5–6. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Motor neuron disease includes a heterogeneous group of relentless progressive neurological disorders defined and characterized by the degeneration of motor neurons. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso