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Mostrando 1,201 - 1,213 Resultados de 1,213 Para Buscar '"motor neurone disease"', tiempo de consulta: 5.67s Limitar resultados
  1. 1201
    “…Concomitant pathology was only present in one of the non-CTE cases (Lewy body) and one of the CTE cases (motor neuron disease). There was a strong association between flortaucipir SUVRs and p-tau density in the composite cortical (ρ = 0.71) and limbic (ρ = 0.77) ROIs. …”
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    Associations between near end-of-life flortaucipir PET and postmortem CTE-related tau neuropathology in six former American football players
  2. 1202
    “…BACKGROUND: Certain murine leukemia viruses (MLVs) are capable of inducing progressive spongiform motor neuron disease in susceptible mice upon infection of the central nervous system (CNS). …”
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    Gene expression profiling of microglia infected by a highly neurovirulent murine leukemia virus: implications for neuropathogenesis
  3. 1203
    “…Multiple missense mutations at the CAP-Gly domain of p150(Glued) are associated with motor neuron diseases and other neurodegenerative disorders, further supporting the importance of microtubule domains (MTBDs) in p150(Glued) functions. …”
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    Genetic ablation of dynactin p150(Glued) in postnatal neurons causes preferential degeneration of spinal motor neurons in aged mice
  4. 1204
    Publicado 2019
    “…METHODS: We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. …”
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    Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
  5. 1205
    “…While historically considered a motor neuron disease, current understanding of SMA emphasizes its systemic nature, which requires addressing affected peripheral tissues such as skeletal muscle in particular. …”
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    Mechanisms of exercise‐induced survival motor neuron expression in the skeletal muscle of spinal muscular atrophy‐like mice
  6. 1206
    “…BACKGROUND: Spinal muscular atrophy (SMA) is an autosomal-recessive motor neuron disease leading to dysfunction of multiple organs. …”
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    Quality of life of children with spinal muscular atrophy and their caregivers from the perspective of caregivers: a Chinese cross-sectional study
  7. 1207
    “…The clinical accuracy of whole genome sequencing to detect repeat expansions was prospectively examined in previously genetically tested and undiagnosed patients recruited in 2013–17 to the 100 000 Genomes Project in the UK, who were suspected of having a genetic neurological disorder (familial or early-onset forms of ataxia, neuropathy, spastic paraplegia, dementia, motor neuron disease, parkinsonian movement disorders, intellectual disability, or neuromuscular disorders). …”
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    Whole genome sequencing for the diagnosis of neurological repeat expansion disorders in the UK: a retrospective diagnostic accuracy and prospective clinical validation study
  8. 1208
    “…Background: Amyotrophic lateral sclerosis (ALS) is a devastating and untreatable motor neuron disease, with a 3–5-year survival from diagnosis. …”
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    Neutrophils-to-Lymphocyte Ratio Is Associated with Progression and Overall Survival in Amyotrophic Lateral Sclerosis
  9. 1209
    “…Although mechanisms of this association are unknown, hyperparathyroidism mimics motor neuron disease and skeletal muscle is a target organ for PTH, decreasing energy production and transport. …”
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    SUN-LB049 Unusual Presentation of Large Parathyroid Adenoma with Acute Cerebellar Ataxia in a Pediatric Patient
  10. 1210
    “…OBJECTIVE: Spinal muscular atrophy (SMA) is a progressive autosomal recessive motor neuron disease caused by loss of the SMN1 gene. Based on randomized clinical trials in children with SMA type 1 and 2, Nusinersen has been approved as the first treatment for all types of SMA, including adults with SMA type 3. …”
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    Safety and Treatment Effects of Nusinersen in Longstanding Adult 5q-SMA Type 3 – A Prospective Observational Study
  11. 1211
    “…Motor neuron diseases such as spinal cord injuries and amyotrophic lateral sclerosis are known as the most common disorders worldwide. …”
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    Large-scale analysis of MicroRNA expression in motor neuron-like cells derived from human umbilical cord blood mesenchymal stem cells
  12. 1212
    por Feigin, Valery L., Vos, Theo, Alahdab, Fares, Amit, Arianna Maever L., Bärnighausen, Till Winfried, Beghi, Ettore, Beheshti, Mahya, Chavan, Prachi P., Criqui, Michael H., Desai, Rupak, Dhamminda Dharmaratne, Samath, Dorsey, E. Ray, Wilder Eagan, Arielle, Elgendy, Islam Y., Filip, Irina, Giampaoli, Simona, Giussani, Giorgia, Hafezi-Nejad, Nima, Hole, Michael K., Ikeda, Takayoshi, Owens Johnson, Catherine, Kalani, Rizwan, Khatab, Khaled, Khubchandani, Jagdish, Kim, Daniel, Koroshetz, Walter J., Krishnamoorthy, Vijay, Krishnamurthi, Rita V., Liu, Xuefeng, Lo, Warren David, Logroscino, Giancarlo, Mensah, George A., Miller, Ted R., Mohammed, Salahuddin, Mokdad, Ali H., Moradi-Lakeh, Maziar, Morrison, Shane Douglas, Shivamurthy, Veeresh Kumar N., Naghavi, Mohsen, Nichols, Emma, Norrving, Bo, Odell, Christopher M., Pupillo, Elisabetta, Radfar, Amir, Roth, Gregory A., Shafieesabet, Azadeh, Sheikh, Aziz, Sheikhbahaei, Sara, Shin, Jae Il, Singh, Jasvinder A., Steiner, Timothy J., Stovner, Lars Jacob, Wallin, Mitchell Taylor, Weiss, Jordan, Wu, Chenkai, Zunt, Joseph Raymond, Adelson, Jaimie D., Murray, Christopher J. L.
    Publicado 2020
    “…Fourteen major neurological disorders were analyzed: stroke, Alzheimer disease and other dementias, Parkinson disease, epilepsy, multiple sclerosis, motor neuron disease, migraine, tension-type headache, traumatic brain injury, spinal cord injuries, brain and other nervous system cancers, meningitis, encephalitis, and tetanus. …”
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    Burden of Neurological Disorders Across the US From 1990-2017: A Global Burden of Disease Study
  13. 1213
    “…HIV), diabetes mellitus, active pulmonary tuberculosis, past history of any chronic respiratory disease, motor neuron disease, multiple sclerosis, stroke, impaired cognition, atrial fibrillation, acute coronary syndrome, myocardial infarction, severe arrhythmia, concurrent serious hepatic disease or renal disease, pregnant or lactating women, patients on immunosuppressive medications, history of hypersensitivity to the trial drugs or their ingredients, depressive illness (before COVID-19), diagnosed psychotic illnesses, substance dependence or alcoholism will be excluded. …”
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    Safety and efficacy of Ayurvedic interventions and Yoga on long term effects of COVID-19: A structured summary of a study protocol for a randomized controlled trial
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