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  1. 2081
    “…Genetic discovery from the multitude of phenotypes extractable from routine healthcare data can transform our understanding of the human phenome and accelerate progress towards precision medicine. …”
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    Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank
  2. 2082
    por Glazer, Robert I., Kopelovich, Levy
    Publicado 2017
    “…PREFACE: The nuclear receptor superfamily members PPARγ and PPARδ regulate gene expression associated with a multitude of pathways, including intermediary metabolism, angiogenesis, proliferation and inflammation (see reviews [1–3]). …”
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    PPARs as determinants of the estrogen receptor lineage: use of synthetic lethality for the treatment of estrogen receptor-negative breast cancer
  3. 2083
    “…In this review, we have provided an overview of the various virus species currently being investigated for their oncolytic potential and the positive and negative effects of a multitude of modifications used to increase their infectivity, anti-tumor immunity, and treatment safety, in particular focusing on the interaction of tumor cells and OVs.…”
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    Oncolytic Viruses—Interaction of Virus and Tumor Cells in the Battle to Eliminate Cancer
  4. 2084
    “…These microorganisms contain a multitude of molecules that may be associated with the complex interaction of the fungus with the host. …”
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    Involvement of Dihydrolipoyl Dehydrogenase in the Phagocytosis and Killing of Paracoccidioides brasiliensis by Macrophages
  5. 2085
    “…Additional comparative profiling with the immunopeptidome of a variety of benign sources has unveiled a multitude of ovarian cancer antigens (MUC16, MSLN, LGALS1, IDO1, KLK10) to be presented by HLA class I and class II molecules exclusively on ovarian cancer cells. …”
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    The immunopeptidomic landscape of ovarian carcinomas
  6. 2086
    “…One approach that may enhance the likelihood of success is to reposition drugs against a target that has a genetic basis. The multitude of genome-wide association studies (GWASs) conducted in recent years represents a large potential pool of novel targets for drug repositioning. …”
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    Enhancing the Promise of Drug Repositioning through Genetics
  7. 2087
    “…Here, we introduce and evaluate a multitude of metal-oxide bi-layers and demonstrate the benefits from increased memory stability via multibit memory operation. …”
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    Multibit memory operation of metal-oxide bi-layer memristors
  8. 2088
    por Kaur, Parampreet, Gaikwad, Kishor
    Publicado 2017
    “…Though initially this approach was developed as an alternative to whole genome sequencing (WGS), but the multitude of benefits conferred by sequence capture via hybridization approaches created a niche for itself to solve many of biological riddles, particularly for resolving phylogenetic distances. …”
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    From Genomes to GENE-omes: Exome Sequencing Concept and Applications in Crop Improvement
  9. 2089
    por Zerbino, Daniel R, Achuthan, Premanand, Akanni, Wasiu, Amode, M Ridwan, Barrell, Daniel, Bhai, Jyothish, Billis, Konstantinos, Cummins, Carla, Gall, Astrid, Girón, Carlos García, Gil, Laurent, Gordon, Leo, Haggerty, Leanne, Haskell, Erin, Hourlier, Thibaut, Izuogu, Osagie G, Janacek, Sophie H, Juettemann, Thomas, To, Jimmy Kiang, Laird, Matthew R, Lavidas, Ilias, Liu, Zhicheng, Loveland, Jane E, Maurel, Thomas, McLaren, William, Moore, Benjamin, Mudge, Jonathan, Murphy, Daniel N, Newman, Victoria, Nuhn, Michael, Ogeh, Denye, Ong, Chuang Kee, Parker, Anne, Patricio, Mateus, Riat, Harpreet Singh, Schuilenburg, Helen, Sheppard, Dan, Sparrow, Helen, Taylor, Kieron, Thormann, Anja, Vullo, Alessandro, Walts, Brandon, Zadissa, Amonida, Frankish, Adam, Hunt, Sarah E, Kostadima, Myrto, Langridge, Nicholas, Martin, Fergal J, Muffato, Matthieu, Perry, Emily, Ruffier, Magali, Staines, Dan M, Trevanion, Stephen J, Aken, Bronwen L, Cunningham, Fiona, Yates, Andrew, Flicek, Paul
    Publicado 2018
    “…Large amounts of raw data are thus transformed into knowledge, which is made available via a multitude of channels, in particular our browser (http://www.ensembl.org). …”
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    Ensembl 2018
  10. 2090
    por Ashraf, Md. Izhar, Sinha, Sitabhra
    Publicado 2018
    “…Language, which allows complex ideas to be communicated through symbolic sequences, is a characteristic feature of our species and manifested in a multitude of forms. Using large written corpora for many different languages and scripts, we show that the occurrence probability distributions of signs at the left and right ends of words have a distinct heterogeneous nature. …”
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    The “handedness” of language: Directional symmetry breaking of sign usage in words
  11. 2091
    por Chosa, Naoyuki, Ishisaki, Akira
    Publicado 2018
    “…Upon activation by tissue damage, MSCs contribute to tissue repair through a multitude of processes such as self-renewal, migration, and differentiation. …”
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    Two novel mechanisms for maintenance of stemness in mesenchymal stem cells: SCRG1/BST1 axis and cell–cell adhesion through N-cadherin()
  12. 2092
    “…In this study, the recombinant human secreted ecto-domain of the small isoform of Stabilin-2 (s190) was purified from cell culture and evaluated for direct binding with a multitude of antisense oligonucleotides (ASOs) using a fluorescence polarization-based assay. …”
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    Structural Determinants for the Interactions of Chemically Modified Nucleic Acids with the Stabilin-2 Clearance Receptor
  13. 2093
    “…Microresonator frequency combs harness the nonlinear Kerr effect in an integrated optical cavity to generate a multitude of phase-locked frequency lines. The line spacing can reach values in the order of 100 GHz, making it an attractive multi-wavelength light source for applications in fiber-optic communications. …”
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    High-order coherent communications using mode-locked dark-pulse Kerr combs from microresonators
  14. 2094
    “…As miRNAs regulate a multitude of targets, the analysis of differentially expressed proteins upon a genomic knock-out (KO) is of interest. …”
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    A proteomic analysis of an in vitro knock-out of miR-200c
  15. 2095
    “…The process is strictly guided and involves a multitude of proteins and regulatory complexes. Unfortunately, aberrant splicing events have been linked to genetic disorders. …”
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    The Usage of Exon-Exon Splice Junctions for the Detection of Alternative Splicing using the REIDS model
  16. 2096
    “…A multitude of biological processes are enabled by complex interactions between lipid membranes and proteins. …”
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    Resolving molecule-specific information in dynamic lipid membrane processes with multi-resonant infrared metasurfaces
  17. 2097
    por Verdorfer, Tobias, Gaub, Hermann E.
    Publicado 2018
    “…Furthermore, our results indicate that certain cohesins undergo a transition from a multitude of different folds or unfolding pathways to a single stable fold upon binding their ligand.…”
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    Ligand Binding Stabilizes Cellulosomal Cohesins as Revealed by AFM-based Single-Molecule Force Spectroscopy
  18. 2098
    “…Medical 3D printing holds the potential of transforming personalized medicine by enabling the fabrication of patient-specific implants, reimagining prostheses, developing surgical guides to expedite and transform surgical interventions, and enabling a growing multitude of specialized applications. In order to realize this tremendous potential in frontline medicine, an understanding of the basic principles of 3D printing by the medical professionals is required. …”
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    Medical 3D printing for vascular interventions and surgical oncology: a primer for the 2016 radiological society of North America (RSNA) hands-on course in 3D printing
  19. 2099
    “…Our results reveal a multitude of paths toward clonal expansions with a wide range of effects on human health.…”
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    Insights about clonal hematopoiesis from 8,342 mosaic chromosomal alterations
  20. 2100
    “…Long non-coding RNAs (lncRNAs) are able to be involved in multitudes of cellular processes in diverse human diseases. …”
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    Knockdown of lncRNA MIR31HG inhibits cell proliferation in human HaCaT keratinocytes
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